HOME >> MEDICINE >> NEWS
How to lose weight and not go hungry: HU researcher develops drug that mimics feeling of 'fullness'

Jerusalem, June 6, 2007 -- Millions of people the world over suffer today from obesity, yet there is no magic bullet that has yet provided a universally accepted solution. However, a young researcher at the Hebrew University of Jerusalem feels he has come up with a practical weight loss solution for the obese person without his having to feel hungry.

For this development, Yaniv Linde, a 32-year-old Ph.D. student of Prof. Chaim Gilon in the Department of Organic Chemistry at the Hebrew University, has been named a first place winner of a Kaye Innovation Award, which was presented today (June 6) during the 70th meeting of the Hebrew University Board of Governors.

Linde and his associates have developed a compound that mimics the activity of the naturally occurring hormone called aMSH. This hormone is naturally excreted during eating and binds to a receptor in the brain called MC4R. When this communication occurs on a substantial level, the brain sends out a signal that one feels full.

The young Hebrew university researchers developed a novel method for synthesizing a peptide (a peptide is a compound linking two or more amino acids) which can serve as an analog to the naturally occurring aMSH hormone. They were able to demonstrate that their peptide, which they call BL-3020, displayed good metabolic stability to intestinal enzymes when swallowed, and that it was able to cross the intestinal wall and gain access into the blood stream. Once in the blood, it could make its way to the MC4R receptor and close the circuit to send out the full signal.

The result is that a person seriously wishing to overcome obesity could take this compound orally in order to curb his appetite, thus leading to natural weight loss. In experiments with mice, it was shown that a single oral administration of BL-3020 led to reduced consumption over a period of 24 hours. Over a 12-day period of daily dosages, the mice weighed 40 percent less than th
'"/>

Contact: Jerry Barach
jerryb@savion.huji.ac.il
972-258-82904
The Hebrew University of Jerusalem
6-Jun-2007


Page: 1 2

Related medicine news :

1. Born to lose: How birth weight affects adult health and success
2. Studies show role of age, gender, race and weight on cancer risk and treatment
3. Healthy body weight throughout adulthood may help delay disability
4. Full-term, low-birth-weight babies at significantly greater risk for early respiratory symptoms
5. Alzheimers weight gain initiative also improved patients intellectual abilities
6. Low physical activity can improve fitness levels for sedentary, overweight postmenopausal women
7. Calcium plus vitamin D supplements may help prevent weight gain in postmenopausal women
8. Eggs promote weight loss and help close nutrient consumption gap
9. Free weight training gets workers with rotator cuff injuries back on the job
10. Simple system accurately predicts weight-loss surgery risk
11. Biopsy may underestimate prostate cancer in obese and overweight men

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/29/2017)... , ... March 29, 2017 , ... In the United ... 300,000 people each year develop other types of metastatic brain tumors(3). Though most meningiomas ... brain(3). As efforts focus on finding more effective treatment options, the San Diego ...
(Date:3/29/2017)... , ... March 30, 2017 , ... Youth Futures International ... success and feedback from high school and college students who have participated in the ... July 7-23 and YFI is now accepting applications for enrollment. Visit http://www.ghana.yfiexperience.org ...
(Date:3/29/2017)... ... March 29, 2017 , ... The Wall Centre ... to new patients from Burnaby, BC. Patients in need of experienced orthodontics, laser ... can see the esteemed team at Wall Centre Dental. Drs. Parviz Roshan, Siamak ...
(Date:3/29/2017)... ... March 29, 2017 , ... How big ... outpatient facilities, and who are the most active developers? , In the ... Healthcare Real Estate Insights (HREI) found that outpatient medical real estate development projects ...
(Date:3/29/2017)... Ca (PRWEB) , ... March 29, 2017 , ... ... process in many scientific laboratories. The assembly protocols involve many repetitive steps and ... suited for automation, which enables the high-throughput needed, and results in a lower ...
Breaking Medicine News(10 mins):
(Date:3/29/2017)... Research and Markets has announced the addition of the ... ... lifestyle drugs market to grow at a CAGR of 2.87% during ... Market 2017-2021, has been prepared based on an in-depth market analysis ... and its growth prospects over the coming years. The report also ...
(Date:3/29/2017)... , Mar 29, 2017 Research and ... Market - Forecast to 2023" report to their offering. ... The ablation device ... to reach $20,995.5 million by 2023. Ablation is ... range of purposes, from cancerous or diseased tissue removal, to the ...
(Date:3/29/2017)... DIEGO , March 29, 2017  NuVasive, ... focused on transforming spine surgery with minimally disruptive, ... Administration (FDA) 510(k) clearance of the CoRoent® Small ... multiple contiguous levels in the cervical spine. This ... cage to be used at up to four ...
Breaking Medicine Technology:
Cached News: