HOME >> MEDICINE >> NEWS
How to lose weight and not go hungry: HU researcher develops drug that mimics feeling of 'fullness'

Jerusalem, June 6, 2007 -- Millions of people the world over suffer today from obesity, yet there is no magic bullet that has yet provided a universally accepted solution. However, a young researcher at the Hebrew University of Jerusalem feels he has come up with a practical weight loss solution for the obese person without his having to feel hungry.

For this development, Yaniv Linde, a 32-year-old Ph.D. student of Prof. Chaim Gilon in the Department of Organic Chemistry at the Hebrew University, has been named a first place winner of a Kaye Innovation Award, which was presented today (June 6) during the 70th meeting of the Hebrew University Board of Governors.

Linde and his associates have developed a compound that mimics the activity of the naturally occurring hormone called aMSH. This hormone is naturally excreted during eating and binds to a receptor in the brain called MC4R. When this communication occurs on a substantial level, the brain sends out a signal that one feels full.

The young Hebrew university researchers developed a novel method for synthesizing a peptide (a peptide is a compound linking two or more amino acids) which can serve as an analog to the naturally occurring aMSH hormone. They were able to demonstrate that their peptide, which they call BL-3020, displayed good metabolic stability to intestinal enzymes when swallowed, and that it was able to cross the intestinal wall and gain access into the blood stream. Once in the blood, it could make its way to the MC4R receptor and close the circuit to send out the full signal.

The result is that a person seriously wishing to overcome obesity could take this compound orally in order to curb his appetite, thus leading to natural weight loss. In experiments with mice, it was shown that a single oral administration of BL-3020 led to reduced consumption over a period of 24 hours. Over a 12-day period of daily dosages, the mice weighed 40 percent less than th
'"/>

Contact: Jerry Barach
jerryb@savion.huji.ac.il
972-258-82904
The Hebrew University of Jerusalem
6-Jun-2007


Page: 1 2

Related medicine news :

1. Born to lose: How birth weight affects adult health and success
2. Studies show role of age, gender, race and weight on cancer risk and treatment
3. Healthy body weight throughout adulthood may help delay disability
4. Full-term, low-birth-weight babies at significantly greater risk for early respiratory symptoms
5. Alzheimers weight gain initiative also improved patients intellectual abilities
6. Low physical activity can improve fitness levels for sedentary, overweight postmenopausal women
7. Calcium plus vitamin D supplements may help prevent weight gain in postmenopausal women
8. Eggs promote weight loss and help close nutrient consumption gap
9. Free weight training gets workers with rotator cuff injuries back on the job
10. Simple system accurately predicts weight-loss surgery risk
11. Biopsy may underestimate prostate cancer in obese and overweight men

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... The pandemic and topsy-turvy economic outlook continues ... our budgets and look for ways to trim the fat from our monthly expenses and ... finances, but it’s also important that you have a financial safety net in place in ...
(Date:8/31/2020)... ... 31, 2020 , ... Bonde Innovations, LLC, a venture-backed developer ... failure, today announced that the company has been awarded a Phase 1 Small ... Heart, Lung, and Blood Institute of the National Institutes of Health (NIH). The ...
(Date:8/28/2020)... ... August 28, 2020 , ... The 15 scholarships being ... Health & Wellness mobile app and web-portal. NCPCV received a 2020 grant from ... grants each year to organizations, such as Destination Imagination, which support and advance ...
(Date:8/28/2020)... ... August 28, 2020 , ... ... that strongly suggest that obese individuals are at an increased risk of developing ... more likely to catch COVID-19; however, because the same organ systems that the ...
(Date:8/26/2020)... ... 26, 2020 , ... Smile Brands Inc. CEO, Steven C. ... leading a session entitled, “A CEO Guide for Delivering and Measuring Inclusion Success”. ... bring together the world’s leading diversity and inclusion executives, HR consultants, and D&I ...
Breaking Medicine News(10 mins):
(Date:8/27/2020)... Calif. (PRWEB) , ... August 27, 2020 , ... ... the conclusion of its fundraising initiative for Feeding San Diego with a ... What: The GHT Companies presents the final check of $5,000.00+ representing an overall donation ...
(Date:8/26/2020)... DIEGO (PRWEB) , ... August 26, 2020 , ... AseptiScope, ... 2020 Infection Control Company of the Year by MedTech Outlook. , “AseptiScope ... Officer. “For the first time, clinicians who wear gloves on their hands, goggles on ...
(Date:8/26/2020)... , ... August 26, 2020 , ... ... in-home air purification systems kill Coronavirus. While air purification technologies, including GreenTech Environmental’s ... SARS and even Ebola, no air purification system has published results of singular ...
Breaking Medicine Technology:
Cached News: