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How tumors respond to treatment prior to liver transplants may be useful in selecting recipients

treatment. "While the authors advocate using response to TACE alone as a selection criterion for OLT in patients with HCC, questions still remain regarding the practicality of this approach," the editorial states. He concludes that the study's findings support the basic principle behind reducing tumor size in HCC patients before transplant, because this may eliminate the most aggressive tumors. However, response to this type of treatment is probably not enough by itself. The author concludes: "Rather than replacing tumor size and number, response to TACE or other loco-regional therapy should be an important endpoint used in conjunction with an upper limit in tumor size and number in refining the existing selection criteria for OLT."


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Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
1-Aug-2006


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