HOME >> MEDICINE >> NEWS
Human antibodies protect mice from avian flu

An international team of scientists, including researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, report using antibodies derived from immune cells from recent human survivors of H5N1 avian influenza to successfully treat H5N1-infected mice as well as protect them from an otherwise lethal dose of the virus.

"The possibility of an influenza pandemic, whether sparked by H5N1 or another influenza virus to which humans have no natural immunity, is of serious concern to the global health community," says NIAID Director Anthony S. Fauci, M.D. "If the success of this initial study is confirmed through further laboratory and clinical trials, human monoclonal antibodies could prove to be valuable therapeutic and prophylactic public health interventions for pandemic influenza."

The research, to be published May 29 in PLoS Medicine, represents a three-way collaboration among Kanta Subbarao, M.D., and her coworkers at NIAID; Antonio Lanzavecchia, M.D., and colleagues from the Institute for Research in Biomedicine, Bellinzona, Switzerland; and Cameron Simmons, Ph.D., from the Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.

Four Vietnamese adults diagnosed with H5N1 influenza infection between January 2004 and February 2005 agreed to donate blood soon after they had recovered from their illness. In Switzerland, Dr. Lanzavecchia extracted antibody-producing white blood cells, called memory B cells, from the Vietnamese samples and treated them with a process he developed so that they rapidly and continuously produced large amounts of antibody. Next, researchers in Dr. Subbarao's lab screened 11,000 antibody-containing samples provided by the Swiss team and found a handful able to neutralize H5N1 influenza virus. Based on these results, Dr. Lanzavecchia purified the B cells and ultimately created four monoclonal antibodies
'"/>

Contact: Anne A. Oplinger
aoplinger@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
28-May-2007


Page: 1 2 3

Related medicine news :

1. Human stem cell treatment restores motor function in paralyzed rats
2. Human circadian clocks couple to local sun time
3. Global Environmental Change and Human Health: New project launched at GEC Conference in Beijing
4. Human brain region functions like digital computer, says CU-Boulder professor
5. Human rights abuses frequent in Haitis capital
6. Humanitarian response urgently needed to address Lebanese health crisis
7. Human Factors research highlights ways to improve patient safety
8. AstraZeneca, University of Miami, and Humana collaborate to improve consumer health
9. Humans ignore motion and other cues in favor of a fictional stable world
10. Human eggs can develop from ovarian surface cells in vitro
11. Institute of Medicine news: Human resource crisis in HIV/AIDS

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Human antibodies protect mice from avian flu

(Date:6/30/2015)... ... June 30, 2015 , ... ... partnership with Knockout Zone Miami (KO Zone), a state-of-the-art training ... and CrossFit Coach, Diego de Vera. The partnership will provide KO Zone clients ...
(Date:6/30/2015)... ... June 30, 2015 , ... Due to today’s housing market, many people cannot afford to “down ... have to make adjustments as to how to carry laundry or groceries from one level ... in the basement or first floor of the home, and the bedrooms are located on ...
(Date:6/30/2015)... ... ... The campaign aims to make digestive wellness a more conversational topic, educating ... 70 million Americans face and inspiring readers to be more proactive by providing them ... component of “Digestive Wellness” is distributed within USA Today in Los Angeles, New York, ...
(Date:6/30/2015)... ... June 30, 2015 , ... Experts estimate that up to ... Back pain can range from a dull, constant ache (chronic) to a sudden sharp ... epidural steroid injections, selective nerve root blocks and rhizotomy treatment, OPTIMAL Pain & ...
(Date:6/30/2015)... ... 2015 , ... It has become fairly common to purchase fresh broccoli at ... stalks before cooking. Throwing out radish greens, beet leaves and chard stalks is pretty ... just takes a little knowledge and practice to use them. Josie's Organics ...
Breaking Medicine News(10 mins):Health News:Top Sports Nutrition Brand, Liporidex, Announces Partnership With Leading Boxing, CrossFit and MMA Gym, Knockout Zone of Miami 2Health News:Top Sports Nutrition Brand, Liporidex, Announces Partnership With Leading Boxing, CrossFit and MMA Gym, Knockout Zone of Miami 3Health News:Butler Mobility Products announce a Solution to Carry Items from One Floor to the Next with a Dumbwaiter 2Health News:Mediaplanet’s “Digestive Wellness” Campaign Urges You To Listen to What Your Stomach Is Telling You and Talk About It 2Health News:OPTIMAL Pain & Regenerative Medicine Brings Innovative Back Pain Management Options Including PRP Injections and Stem Cell-like Therapies to Dallas/Ft. Worth Metroplex 2Health News:OPTIMAL Pain & Regenerative Medicine Brings Innovative Back Pain Management Options Including PRP Injections and Stem Cell-like Therapies to Dallas/Ft. Worth Metroplex 3Health News:Whole Vegetable Cooking for Home Cooks: Josie's Organics Encourages Using All Parts of Vegetables – from Root to Stalk – Every Day 2Health News:Whole Vegetable Cooking for Home Cooks: Josie's Organics Encourages Using All Parts of Vegetables – from Root to Stalk – Every Day 3Health News:Whole Vegetable Cooking for Home Cooks: Josie's Organics Encourages Using All Parts of Vegetables – from Root to Stalk – Every Day 4
(Date:6/30/2015)... -- July 4 th is this weekend, a time we ... people behind it. To help honor our current nation,s heroes, ... Medical Card, a leading provider of free pharmacy ... independence for our disabled military veterans, police, firemen, and EMS ... prescriptions. "Due to USA ...
(Date:6/30/2015)... Minn. , June 30, 2015  EnteroMedics Inc. ... devices that use neuroblocking technology to treat obesity, metabolic ... its previously announced public offering  of 40,229,886 units. Each ... of a Series A warrant to purchase one share ... warrant to purchase one share of common stock, at ...
(Date:6/30/2015)... 2015  Marken, the leading clinical trial logistics organization ... has been granted permission by the government to deliver ... product in Korea.  This precedent-setting shipment has allowed several ... continue receiving their clinical trial drugs during the outbreak ... emergency was caused by recent partial closures of medical ...
Breaking Medicine Technology:Hope For Heroes and USA Medical Card Make a Difference for Our Nation's Heroes 2EnteroMedics Inc. Announces Pricing of $35.0 Million Public Offering of Common Stock and Warrants 2EnteroMedics Inc. Announces Pricing of $35.0 Million Public Offering of Common Stock and Warrants 3Marken Delivers Direct To Patients During MERS Outbreak 2Marken Delivers Direct To Patients During MERS Outbreak 3
Cached News: