HOME >> MEDICINE >> NEWS
Human antibodies protect mice from avian flu

An international team of scientists, including researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, report using antibodies derived from immune cells from recent human survivors of H5N1 avian influenza to successfully treat H5N1-infected mice as well as protect them from an otherwise lethal dose of the virus.

"The possibility of an influenza pandemic, whether sparked by H5N1 or another influenza virus to which humans have no natural immunity, is of serious concern to the global health community," says NIAID Director Anthony S. Fauci, M.D. "If the success of this initial study is confirmed through further laboratory and clinical trials, human monoclonal antibodies could prove to be valuable therapeutic and prophylactic public health interventions for pandemic influenza."

The research, to be published May 29 in PLoS Medicine, represents a three-way collaboration among Kanta Subbarao, M.D., and her coworkers at NIAID; Antonio Lanzavecchia, M.D., and colleagues from the Institute for Research in Biomedicine, Bellinzona, Switzerland; and Cameron Simmons, Ph.D., from the Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.

Four Vietnamese adults diagnosed with H5N1 influenza infection between January 2004 and February 2005 agreed to donate blood soon after they had recovered from their illness. In Switzerland, Dr. Lanzavecchia extracted antibody-producing white blood cells, called memory B cells, from the Vietnamese samples and treated them with a process he developed so that they rapidly and continuously produced large amounts of antibody. Next, researchers in Dr. Subbarao's lab screened 11,000 antibody-containing samples provided by the Swiss team and found a handful able to neutralize H5N1 influenza virus. Based on these results, Dr. Lanzavecchia purified the B cells and ultimately created four monoclonal antibodies
'"/>

Contact: Anne A. Oplinger
aoplinger@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
28-May-2007


Page: 1 2 3

Related medicine news :

1. Human stem cell treatment restores motor function in paralyzed rats
2. Human circadian clocks couple to local sun time
3. Global Environmental Change and Human Health: New project launched at GEC Conference in Beijing
4. Human brain region functions like digital computer, says CU-Boulder professor
5. Human rights abuses frequent in Haitis capital
6. Humanitarian response urgently needed to address Lebanese health crisis
7. Human Factors research highlights ways to improve patient safety
8. AstraZeneca, University of Miami, and Humana collaborate to improve consumer health
9. Humans ignore motion and other cues in favor of a fictional stable world
10. Human eggs can develop from ovarian surface cells in vitro
11. Institute of Medicine news: Human resource crisis in HIV/AIDS

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Human antibodies protect mice from avian flu

(Date:8/3/2015)... ... August 03, 2015 , ... ... to decline by 39 percent, according to market research compiled for the National ... from the U.S. Department of Labor, Bureau of Labor Statistics. As the number ...
(Date:8/3/2015)... ... August 03, 2015 , ... Constantin Vasilica, 48 from Romania wanted to have ... diabetes after many years of suffering and using medications with strong side effects. This ... ask for extra time off or wait longer hours in the waiting rooms. Instead, ...
(Date:8/3/2015)... ... ... The American Institute of Architects (AIA) and ... a wide range of initiatives ranging from code development and compliance to sustainability ... membership, consisting of practicing design professionals, code officials, and the building industry representatives, ...
(Date:8/2/2015)... ... 2015 , ... A new Phase I research study is looking at a ... by Kenneth G. Lucas, M.D. , chief of the division of pediatric hematology/oncology ... Kosair Children’s Hospital and in the UofL Department of Pediatrics . ...
(Date:8/1/2015)... ... , ... AlignLife Office Coordinator Heather Pugh earned the position of ... at this natural health care center in Winamac. , "Oftentimes patients are in pain ... is vital to our approach because we want to focus on the patient wants ...
Breaking Medicine News(10 mins):Health News:Dental Association Announces Impending Reduction of Dental Laboratories Could Impact Dentists 2Health News:Dental Association Announces Impending Reduction of Dental Laboratories Could Impact Dentists 3Health News:Chinese Health Care Provider Heshoutang Now Give Patients Complimentary Online Healing Options 2Health News:Chinese Health Care Provider Heshoutang Now Give Patients Complimentary Online Healing Options 3Health News:Architects, International Code Council Ink Five-Year Collaborative Agreement 2Health News:Architects, International Code Council Ink Five-Year Collaborative Agreement 3Health News:UofL Physicians Conducting Vaccine Trial for Children with Relapsed Tumors at Kosair Children’s Hospital 2Health News:New Patient Advocate Enhances Natural Health Care 2
(Date:7/31/2015)... CHICAGO , July 31, 2015 ... Market by Product (Moist Heat, Dry Heat, Ethylene Oxide, Filtration, ... & End User (Hospitals, Pharmaceuticals) - Global Forecast to 2020", ... reach around USD 6.1 Billion by 2020, at a CAGR ... 242 market data T ables and ...
(Date:7/31/2015)... WAYNE, Pa. , July 31, 2015 /PRNewswire/ ... a fully integrated specialty pharmaceutical company focused on ... announced the closing of its previously announced underwritten ... stock at a public offering price of $11.25 ... the offering included 1,000,000 shares issued upon the ...
(Date:7/31/2015)...  Xencor, Inc. (NASDAQ: XNCR ), a clinical-stage ... of autoimmune diseases, asthma and allergic diseases, and cancer, ... to its board of directors. ... is a tremendous asset to our board," said ... of Xencor. "Xencor faces a range of opportunities for ...
Breaking Medicine Technology:Sterilization Equipment Market is Expected to Reach USD 6.1 Billion by 2020 2Sterilization Equipment Market is Expected to Reach USD 6.1 Billion by 2020 3Sterilization Equipment Market is Expected to Reach USD 6.1 Billion by 2020 4Egalet Announces Closing of Public Offering of Common Stock and Exercise in Full of Underwriters' Option to Purchase Additional Shares 2Egalet Announces Closing of Public Offering of Common Stock and Exercise in Full of Underwriters' Option to Purchase Additional Shares 3Egalet Announces Closing of Public Offering of Common Stock and Exercise in Full of Underwriters' Option to Purchase Additional Shares 4Xencor Appoints Yujiro S. Hata to Board of Directors 2Xencor Appoints Yujiro S. Hata to Board of Directors 3
Cached News: