HOME >> MEDICINE >> NEWS
Human antibodies protect mice from avian flu

An international team of scientists, including researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, report using antibodies derived from immune cells from recent human survivors of H5N1 avian influenza to successfully treat H5N1-infected mice as well as protect them from an otherwise lethal dose of the virus.

"The possibility of an influenza pandemic, whether sparked by H5N1 or another influenza virus to which humans have no natural immunity, is of serious concern to the global health community," says NIAID Director Anthony S. Fauci, M.D. "If the success of this initial study is confirmed through further laboratory and clinical trials, human monoclonal antibodies could prove to be valuable therapeutic and prophylactic public health interventions for pandemic influenza."

The research, to be published May 29 in PLoS Medicine, represents a three-way collaboration among Kanta Subbarao, M.D., and her coworkers at NIAID; Antonio Lanzavecchia, M.D., and colleagues from the Institute for Research in Biomedicine, Bellinzona, Switzerland; and Cameron Simmons, Ph.D., from the Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.

Four Vietnamese adults diagnosed with H5N1 influenza infection between January 2004 and February 2005 agreed to donate blood soon after they had recovered from their illness. In Switzerland, Dr. Lanzavecchia extracted antibody-producing white blood cells, called memory B cells, from the Vietnamese samples and treated them with a process he developed so that they rapidly and continuously produced large amounts of antibody. Next, researchers in Dr. Subbarao's lab screened 11,000 antibody-containing samples provided by the Swiss team and found a handful able to neutralize H5N1 influenza virus. Based on these results, Dr. Lanzavecchia purified the B cells and ultimately created four monoclonal antibodies
'"/>

Contact: Anne A. Oplinger
aoplinger@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
28-May-2007


Page: 1 2 3

Related medicine news :

1. Human stem cell treatment restores motor function in paralyzed rats
2. Human circadian clocks couple to local sun time
3. Global Environmental Change and Human Health: New project launched at GEC Conference in Beijing
4. Human brain region functions like digital computer, says CU-Boulder professor
5. Human rights abuses frequent in Haitis capital
6. Humanitarian response urgently needed to address Lebanese health crisis
7. Human Factors research highlights ways to improve patient safety
8. AstraZeneca, University of Miami, and Humana collaborate to improve consumer health
9. Humans ignore motion and other cues in favor of a fictional stable world
10. Human eggs can develop from ovarian surface cells in vitro
11. Institute of Medicine news: Human resource crisis in HIV/AIDS

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/18/2017)... (PRWEB) , ... February 17, 2017 , ... ... leading source of disruptive innovation in the industry, according to the recent NEJM ... are based on surveys of the NEJM Catalyst Insights Council, a qualified group ...
(Date:2/18/2017)... ... February 17, 2017 , ... CONTACT:, ... , Beverly Hills plastic surgeon Dr. Glenn Vallecillos experiments SculpSure, the ... says, "Traditionally, plastic surgery has been centered around that idea that to achieve ...
(Date:2/18/2017)... Viejo, CA (PRWEB) , ... February 18, 2017 ... ... animating paragraph presets. Use Pixel Film Studios ’ ProParagraph Fashion Volume ... descriptions, and so many other applications. Users can pick and choose from ...
(Date:2/17/2017)... ... February 17, 2017 , ... Smiles by Seese is a ... Davidson, NC. Dr. Brian Seese leads the practice as a skilled and highly credentialed ... roof. Smiles by Seese serves patients of all ages with excellence in general, restorative, ...
(Date:2/17/2017)... CA (PRWEB) , ... February 17, 2017 , ... ... focus on foundational and sustainable systems change designed to further positively impact the ... “The Board of Trustees has long considered it our duty to seriously consider ...
Breaking Medicine News(10 mins):
(Date:2/18/2017)... , Feb. 17, 2017  Pharmaceutical companies have long used ... either in development or already on the market.   ... pharma industry to alter how it manages advisory board meetings. ... Best Practices, LLC conducted a new study focused on key ... ...
(Date:2/17/2017)... , Feb. 17, 2017  Ethicon, Inc. ... Medical, Inc., a privately held medical device company ... Reflux Management System, a novel minimally invasive device ... of Torax Medical will enable Ethicon to offer ... anatomy-altering laparoscopic Nissen fundoplication surgical procedure. 1 ...
(Date:2/17/2017)... Arvinas LLC, a private biotechnology company creating ... today announced the presentation of new preclinical data on ... session at the American Society of Clinical Oncology 2017 ... FL. "The new data ... potential of PROTACs to drive durable and robust responses ...
Breaking Medicine Technology:
Cached News: