IADR and GlaxoSmithKline Consumer Healthcare announce winners of 2006 Innovation in Oral Care Awards

The International Association for Dental Research (IADR) and GlaxoSmithKline Consumer Healthcare today announced the 2006 winners of the annual IADR/GSK Innovation in Oral Care Awards. The three winners will be recognized during the 84th General Session & Exhibition of the IADR, held in Brisbane, Australia, June 28 July 1, 2006. Sharing the $225,000 unrestricted research grant, which is funded by GSK and administered by the IADR, are:

  • Dr. Hyun (Michel) Koo and co-workers, University of Rochester, USA, for "A Novel Therapeutic Approach to Prevent Formation of Cariogenic Biofilm." These researchers have developed a novel strategy to reduce the development of cariogenic biofilms by combining two naturally occurring anti-caries/anti-plaque agents with fluoride. By integrating molecular and imaging techniques with an in vivo model simulating clinical conditions, the researchers will enhance the understanding of how the compounds modulate the pathogenesis of cariogenic biofilm development, and expand their potential usefulness as a novel chemotherapeutic approach to the prevention of biofilm-related diseases.
  • Dr. Yen-Tung Andy Teng, University of Rochester, USA, for "A Novel Therapeutic Human SCFV-Diabody for Aggressive Periodontitis." This research will evaluate the efficacy regarding the inhibition of periodontal biofilm and tissue inflammation via a bioengineered diabody specific to a virulence factor of Actinobacillus actinomycetemcomitans, a known periodontal pathogen. If successful, a next-generation drug could be developed for periodontal therapy.
  • Dr. Cun-Yu Wang, University of Michigan, USA, and Dr. Lijian Jin, University of Hong Kong, for "Targeting IKK/NF-B for Periodontitis." Through international collaboration, the findings from this research may help to develop innovative compounds, including purified components/extracts from traditional Chinese herbal medicine (TCM), for local delivery of anti-inflammatory drugs to treat perio

Contact: Linda Hemphill
International & American Association for Dental Research

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