HOME >> MEDICINE >> NEWS
Implanting dopamine generators in brain cells obtains improvement in Parkinson's in monkeys

Implanting dopamine generators (dopaminergics) in brain cells has produced improvement in the symptoms in Parkinson's, according to the results of tests carried out with monkeys by the Navarra University Hospital, led by Dr Mara Rosario Luquin Piudo, neurologist at the Hospital and at the other Navarra University-based medical centre, CIMA (the Research Centre for Applied Medicine).

The results have been published in the latest issue of the British scientific journal specialising in Neurology, Brain, and have corroborated the conclusions of a previous study, published in 1999 by the same research team in the specialist journal, Neuron. The first name amongst the contributors is that of the researcher Waldy San Sebastin.

On this occasion the research was extended to a greater number of non- human primates and for a longer period of time. The procedure involved implanting cell fragments extracted from the carotid body in the striate area of the brain. The carotid body is a small structure located at the bifurcation of the carotid artery, at the level of the neck. Its function is to control the rhythm of respiration and the cardiac frequency through releasing dopamine in situations of low oxygen level in the blood. After the implantation of the cellular aggregates of the carotid body into the striate area of the brain, the improvement in movement in monkeys with Parkinson's and which had received transplants was demonstrated to last for at least a year.

The research team concluded that the mechanism by which the implants in the striate area of the brain of dopamine-generating cells manage to ameliorate Parkinson's appears to be related to the capacity of these cells to release substances (trophic factors) that induce an increase of the dopaminergic cells (that usually exist in the normal brain but in lower quantities). Amongst these trophic factors is the GNDF (Glial Cell-derived Neurotrophic Factor).

Cells extr
'"/>

Contact: Egoitz Etxebeste
egoitz@elhuyar.com
Elhuyar Fundazioa
16-May-2007


Page: 1 2 3

Related medicine news :

1. ADHD appears to be associated with depressed dopamine activity in the brain
2. New dopamine brain target discovered
3. Depression linked to previously unknown dopamine regulator
4. Draining away brains toxic protein to stop Alzheimers
5. New research discovers independent brain networks control human walking
6. First of its kind report on how children with brain tumors perform at school
7. Chemical in brain acts like a fuel gauge
8. Case study: cross-cultural bioethics training program helps fight African brain drain
9. Paying taxes, according to the brain, can bring satisfaction
10. Childrens brain responses predict impact of sleep loss on attention
11. Old memory traces in brain may trigger chronic pain

Post Your Comments:
(Date:2/28/2015)... February 28, 2015 Kaylie Corrigan, Outdoor ... treatment center , and current student obtaining her Masters ... implemented a weekly forum in psychoeducation on substance use ... Flagstaff, AZ as part of her studies. , “Even ... for support and counseling at the high school and ...
(Date:2/28/2015)... Viejo, California (PRWEB) February 28, 2015 Developers ... the release of a new overlay plugin for Final Cut ... Film Studios. , “FCPX Overlay Chromatic gives users total control ... said Christina Austin, CEO of Pixel Film Studios. “FCPX Overlay ... maintaining an easy to use interface.” , FCPX Overlay Chromatic ...
(Date:2/28/2015)... 28, 2015 The World Scout League ... materials to potential EMTs and firefighters, recently announced its ... a way to raise charitable donations for age-related research. ... Columbia, will be held on March 29, 2015; registration ... begin at 3:30 p.m. , To participate in ...
(Date:2/27/2015)... OnChip Devices , a world ... wire bondable, silicon ESD (Electrostatic Discharge) protection diodes targeted ... ESD88NP and ESD88PN are designed ... and IC products. These Zeners exhibit no device ... devices meet the requirements of IEC61000 and safely dissipate ...
(Date:2/27/2015)... February 27, 2015 On March ... and the National Cancer Institute (NCI) will co-host ... the National Institutes of Health (NIH), in Bethesda, ... is dedicated to medical professionals and scientists who ... to the general public, including patients, their families, ...
Breaking Medicine News(10 mins):Health News:Staff at Arizona Drug Addiction Treatment Center Starts Teen Sobriety Support Group at Local High School 2Health News:Pixel Film Studios released a new overlay plugin entitled FCPX Overlay Chromatic Grunge 6K exclusively for Final Cut Pro X users 2Health News:Bitcoin Run Is The World Scout League Commission’s Newest Project for Charity 2Health News:OnChip Introduces New Series of Space Saving Bare-die Zener Diodes for Transient Voltage Suppression 2Health News:OnChip Introduces New Series of Space Saving Bare-die Zener Diodes for Transient Voltage Suppression 3Health News:Conference on Mesothelioma Co-Hosted with National Cancer Institute 2Health News:Conference on Mesothelioma Co-Hosted with National Cancer Institute 3
(Date:2/26/2015)... , February 27, 2015 ... 2014 market research report to its store. This ... Ulcers, therapeutic pipeline. The report "Corneal ... the therapeutic development for Corneal Ulcers. Corneal Ulcers ... includes bacterial infections, viral infections & fungal infections. ...
(Date:2/26/2015)... Calif. , Feb. 26, 2015  IRIDEX Corporation (NASDAQ: ... its fourth quarter and full year 2014 financial results after ... In conjunction with the release, the Company will host a ... Eastern Time on Thursday, March 5, 2015 ... developments. Interested parties may access the live conference ...
(Date:2/26/2015)... 26, 2015 Every year many millions of ... heart disease.  Nevertheless, year after year doctors and the ... the first test to determine the status of heart ... or not, even though that technology is over 100 ... that doctors know, (while most patients do not know) ...
Breaking Medicine Technology:Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 2Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 3Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 4Corneal Ulcers Therapeutics Companies and Drugs Pipeline H2 2014 Review Research Report 5IRIDEX Announces Fourth Quarter and Full Year 2014 Conference Call and Release Date 2National Heart Health Month In February 2
Cached News: