Improved adherence to certain medications associated with longer survival following heart attack

New research suggests that the pharmacological effects of taking medications such as statins and beta-blockers as prescribed following a heart attack is associated with living longer, according to a study in the January 10 issue of JAMA.

Clinical trials have demonstrated that selected medications reduce the risk of cardiovascular death. However, their projected survival impact in the real world is less known, in part because of variations in drug adherence, according to background information in the article. Although it is known that adherence to evidence-based medications predicts better survival, no population outcome study has attempted to differentiate whether these associations are attributable to the drug's biological responsiveness (drug effect) or to the adoption of healthier lifestyles that often accompany adherent behaviors (healthy adherer effect).

Jeppe N. Rasmussen, M.D., of the University of Toronto, and colleagues examined the relationship between drug adherence and death following acute myocardial infarction (AMI; heart attack). To help evaluate whether this relationship was more attributable to drug effects rather than to healthy adherer effects, the researchers examined 3 medication classes, 2 of which are associated with proven mortality benefits (statins and beta-blockers); the third medication class (calcium channel blockers) was examined as a control given the absence of documented post-heart attack survival advantages. The study included 31,455 elderly heart attack survivors between 1999 and 2003 in Ontario. All patients filled a prescription for statins, beta-blockers, or calcium channel blockers. Patient adherence was subdivided into 3 categories: high (proportion of days covered, 80 percent or greater), intermediate (proportion of days covered, 40 percent - 79 percent), and low (proportion of days covered, less than 40 percent).

Among patients who used statins, mortality was greatest for low adherers (deaths

Contact: Julie Dowdie
JAMA and Archives Journals

Page: 1 2 3

Related medicine news :

1. Improved neonatal care has helped reduce prevalence of cerebral palsy in premature babies
2. Improved treatment raises medulloblastoma survival rate
3. Improved diagnostic technology for Crohns disease
4. Patient adherence for successful tuberculosis treatment
5. Residents in disaster areas face medication adherence dilemmas
6. Sub-Saharan Africans with HIV may achieve favorable levels of antiretroviral therapy adherence
7. Race affects medication adherence in type 2 diabetes
8. Participation in clinical trials does not appear to affect physicians adherence to guidelines
9. Diagnosis and treatment of osteoporosis falls shortnon adherence compounds issue
10. Faxed alerts to physicians may not improve patient antidepressant adherence
11. Study shows adherence to pulmicort respules, results in fewer ER visits in asthmatic children

Post Your Comments:

(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: