TITLE: Cardiac mast cellderived renin promotes local angiotensin formation, norepinephrine release, and arrhythmias in ischemia/ reperfusion
AUTHOR CONTACT: Roberto Levi
Weill Medical College of Cornell University, New York, New York USA
Phone: (212) 746-6223; Fax: (212) 746-8835; E-mail: rlevi@med.cornell.edu
View the PDF of this article at: https://www.the-jci.org/article.php?id=25713
ACCOMPANYING COMMENTARY:
TITLE: A new cardiac MASTer switch for the renin-angiotensin system
AUTHOR CONTACT: Thomas M. Coffman
VA Medical Center, Durham, North Carolina, USA
Phone: (919) 286-6947; Fax: (919) 286-6879; Email: tcoffman@acpub.duke.edu
View the PDF of this article at: https://www.the-jci.org/article.php?id=28312
ENDOCRINOLOGY
Why girls will be girls: molecular safeguards for female sexual development
In the first trimester of human fetal development, the male and female external genitalia are identical. However, although boy and girl babies begin their development as girls, male genital development will occur if high levels of the male steroid hormone testosterone are present at 712 weeks, which occurs in female fetuses deficient in an enzyme called CYP21, involved in the production of cortisol. This increase in cortisol is the direct result of a related defect called congenital adrenal hyperplas
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Contact: Brooke Grindlinger
press_releases@the-jci.org
212-342-9006
Journal of Clinical Investigation
3-Apr-2006