HOME >> MEDICINE >> NEWS
Jefferson scientists design method to fight artificial implant infections with antibiotics

wall to see if the vancomycin on the powder, or beads, could bind to its natural target. The tests proved that the vancomycin was bound and active.

Finally, they added bacteria and showed that titanium beads with vancomycin on the surface killed the bacteria. When the beads were exposed to more bacteria, the vancomycin continued to kill the new infection. The vancomycin was not only chemically bound, but aggressively curtailed re-infection as well.

The researchers, led by Irving Shapiro, Ph.D., professor of orthopedic surgery at Jefferson Medical College, and including collaborators at the Rothman Institute at Jefferson and the University of Pennsylvania are supported by a grant from the U.S. Department of Defense to develop techniques to protect titanium surfaces with antibiotics.

"The recent results are another step toward our ultimate goal of preventing infections in battlefield fractures and hip and knee implants," Dr. Shapiro says.

"This technology bonding antibiotics to the implant surface is analogous to having land mines," says orthopedic surgeon Javad Parvizi, M.D., who treats implant-related infections and works on the project. "Once the organism steps on the surface, the antibiotic mine explodes and kills the bacteria. It holds great promise for our patients."

When a hip or knee implant is infected, physicians give extensive antibiotic treatment and the old implant is replaced. The treatment can include cement-containing antibiotics. "The hope is that the drugs in the glue will protect the implant, but that doesn't always work," Dr. Hickok explains. She notes that while they are infrequent, such infections can occur right after surgery from contamination during the operation. Later, infections can start on the implant from a different source in the body, such as a bladder infection or a dental procedure.

Dr. Wickstrom says the same approach can be used for other antibiotics and other implants. "There are plastic devices b
'"/>

Contact: Steve Benowitz
steven.benowitz@jefferson.edu
215-955-5291
Thomas Jefferson University
23-Sep-2005


Page: 1 2 3

Related medicine news :

1. Fat protein cuts blood vessel inflammation, may help heart, Jefferson scientists find
2. Jefferson pharmacologist says biomarker discovery bodes well for better cancer diagnostics
3. Jefferson immunology researchers show blood-brain barrier damage could affect MS severity
4. Jefferson scientists find that plavix appears to be safe during and after heart bypass
5. Treatment of in-hospital cardiac patients is focus of Jefferson University presentations
6. Jefferson scientists find that drug-eluting stents are disappointing in bypass grafts -- sometimes
7. Empathy skills must be given a high priority in medical education, says Jefferson author
8. Natural, soy-based substance might help fight MS, Jefferson neuroscientists find
9. Blood pressure drugs could help halt pancreatic cancer spread, Jefferson researchers find
10. Obesity tied to higher risk of complications in spinal surgery, Jefferson neurosurgeon finds
11. Jefferson Orthopaedic surgeons leading international study of timing of spinal surgery

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2017)... ... 26, 2017 , ... LARKR™ , an innovative new smartphone app providing ... the country to join its online treatment platform. , Launching in just a ... substantially greater number of people in need nationwide, and to supplement their traditional practices. ...
(Date:6/25/2017)... ... June 25, 2017 , ... FCPX LUT Vintage Volume 2 for ... look. FCPX LUT Vintage Volume 2 contains 60 different color-grade presets, giving editors multiple ... vignettes and blurs to single out subjects, plus much more. FCPX LUT Vintage Volume ...
(Date:6/25/2017)... ... June 25, 2017 , ... CareSet Labs released the Root NPI Graph ... is a new, greatly improved version of the Doctor Referral teaming dataset commonly available ... Trotter and subsequently called the the “Doctor Referral Dataset” as released by Medicare and ...
(Date:6/24/2017)... (PRWEB) , ... June 24, 2017 , ... ... in Erie, PA at the Sheraton Erie Bayfront and Erie Convention Center on ... based medicine experience, exhibits, a student quiz bowl, award and scholarship presentations, and ...
(Date:6/23/2017)... ... June 23, 2017 , ... ... announced the launch of Care Management Alerts and Dashboards, an innovative new service ... Rhode Island. , RIQI’s Care Management Alerts and Dashboards provide near real-time data ...
Breaking Medicine News(10 mins):
(Date:6/9/2017)... PALO ALTO, Calif. , June 9, 2017 /PRNewswire/ ... medical device company focused on the design, manufacture, sale ... updated the market on the progress of its commercial ... AeroForm is now available in more than one hundred ... country. AeroForm offers a needle-free alternative ...
(Date:6/8/2017)... , June 8, 2017  StatLab Medical ... developer and manufacturer of diagnostic supplies for ... that Cressey & Company LP ("Cressey & ... completed a growth-focused investment in the Company. ... ownership position from selling shareholder, Prairie Capital, ...
(Date:6/5/2017)... 5, 2017 The Cincinnati ... Pharmacy, Inc. (NYSE: DPLO), has been awarded a Top ... Results are based on an employee survey administered ... and workplace improvement. The survey measures several aspects of workplace ... ...
Breaking Medicine Technology:
Cached News: