HOME >> MEDICINE >> NEWS
Johns Hopkins scientists map brain area that may aid hunt for human brain stem cells

A study led by a Johns Hopkins neurosurgeon has provided the first comprehensive map of a part of the adult human brain containing astrocytes, cells known to produce growth factors critical to the regeneration of damaged neural tissue and that potentially serve as brain stem cells. The mapping study -- using special microscopes and chemical analysis of 42 samples of brain tissue taken at autopsy from seven people, and 43 samples of tissue removed with permission from living patients as part of unrelated neurosurgical procedures -- also revealed evidence of the move of cells lining the ventricles, or ependymal cells, to the same area of the brain, a discovery expected to provide further insight into the critical relationship among ependymal cell, astrocytes and potential brain stem cells.

"Although we have not confirmed the existence of human brain stem cells in vivo or their ability to migrate to parts of the brain that need repair, what we have learned from this complete map of the lateral wall of the subventricle zone or SVZ, including the unexpected existence of ependymal cells there, suggests that additional research is warranted," says Alfredo Quinones-Hinojosa, M.D., lead author of the study and an assistant professor in the Department of Neurosurgery at the Johns Hopkins University School of Medicine. "If there is stem-cell-like activity in the SVZ, this discovery could help pave the way for a number of therapeutic treatments for treating brain cancer, neurodegenerative diseases and brain damage."

The subventricle zone refers to tissue and cells that lie next to the ventricles or tubes located in the center of the brain that act as conduits for the cerebral spinal fluid that bathes the entire brain. The ependymal layer is a layer of cells that make up the outer wall of these tubes. Behind that layer lies the SVZ.

Previous studies have shown that astrocytes located in rodent SVZs travel to the olfactory bulb, where they develop into new
'"/>

Contact: Eric Vohr
evohr1@jhmi.edu
410-955-8665
Johns Hopkins Medical Institutions
16-Feb-2006


Page: 1 2 3

Related medicine news :

1. Johns Hopkins begins aggressive screening for superbugs in children
2. Johns Hopkins develops pancreas cancer risk model
3. March of Dimes, Johnson & Johnson Pediatric Institute launch prematurity prevention partnership
4. Diagnosis and referrals for kidney disease fall well short of need, Johns Hopkins study shows
5. Johns Hopkins Childrens Center to lead largest-ever study on kidney disease in children
6. Johns Hopkins lab scientists tame overactive CF protein
7. Two tests better than one for diabetes control, Johns Hopkins expert tells doctors
8. Johns Hopkins scientists exploit novel route to reverse enlarged hearts in obese mice
9. Johns Hopkins study suggests link between caffeine dependence and family history of alcoholism
10. Johns Hopkins flu expert calls for mandatory vaccination of health care workers
11. Nov. 11 event celebrates a century of brain science at Johns Hopkins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... ... 2020 , ... MemoryCare.com, a comprehensive resource for caregivers and ... in Louisville, KY. The guide identifies 17 memory care communities based on location, ... Alzheimer’s Association , 5.6 million people age 65 and older are living with ...
(Date:9/1/2020)... ... , ... KitoTech Medical, a Seattle-based medical device company, announced ... used to accelerate the commercialization of its microMend® family of wound closure products. ... expand its customer base of healthcare systems as well as independent hospitals and ...
(Date:8/31/2020)... ... August 31, 2020 , ... Cardiothoracic surgeons at Allegheny General ... Carnegie Mellon University (CMU) to develop a new heart monitoring device designed to ... surgery. , The AGH/CMU team was recently awarded a “Trailblazer” grant from the ...
(Date:8/31/2020)... NEW YORK (PRWEB) , ... August 31, 2020 , ... ... On September 1, Cerebral Palsy Alliance Research Foundation (CPARF) is thrilled to launch its ... cerebral palsy research. A fully virtual challenge, STEPtember meets everyone wherever they are at ...
(Date:8/31/2020)... Ga. (PRWEB) , ... August 31, 2020 , ... The pandemic and topsy-turvy economic outlook ... examine our budgets and look for ways to trim the fat from our monthly expenses ... your finances, but it’s also important that you have a financial safety net in place ...
Breaking Medicine News(10 mins):
(Date:9/3/2020)... ... 03, 2020 , ... Q&J Face Masks announced today that ... and engineering lab, conducted tests on Q&J’s personal face mask that indicated the ... other masks. Q&J face masks have both mechanical filtering and electrostatic filtering which ...
(Date:9/3/2020)... ... September 03, 2020 , ... In response to the ... schools and classrooms across the United States, IntraLogic Solutions , a leading ... TEMPE is a non-contact, wall-mounted scanning thermometer that rapidly checks body temperatures. When ...
(Date:9/2/2020)... , ... September 02, 2020 ... ... Fight Against Covid-19 , Advanced Penetration Technology, LLC, (APT) a Texas- and ... patients utilizing non-prescription, Over The Counter (OTC) products, was today provided results ...
Breaking Medicine Technology:
Cached News: