Late-breaking science presented at 57th AAN Annual Meeting

MIAMI BEACH The following are late-breaking scientific abstracts that will be presented during the American Academy of Neurology 57th Annual Meeting held in Miami Beach, Fla., April 9 16, 2005.

Rufinamide Reduces Seizures in Treatment-Resistant Lennox-Gastaut Epilepsy

Lennox-Gastaut Syndrome is a catastrophic form of childhood epilepsy that is often resistant to treatment with conventional anti-seizure medications. In this trial, 138 patients with treatment-resistant LGS received either the novel drug rufinamide or placebo for 12 weeks. Rufinamide reduced monthly seizure frequency by 33 percent, compared to 12 percent for placebo, and was especially beneficial in patients with so-called tonic-atonic seizures. Sleepiness and vomiting were important drug side effects. This study provides support for use of the drug in LGS patients whose symptoms are not well controlled by other medications.

New Gene for Charcot-Marie-Tooth Disease Involved in Cell Transport

Charcot-Marie-Tooth disease (CMT), which affects the peripheral nerves, comes in several forms and is due to mutation in a variety of genes. Autosomal dominant CMT of the so-called intermediate form has previously been linked to chromosome 19. In this study, an international team of researchers identified the responsible gene as Dynamin 2 (DNM2), whose protein helps cell membranes fuse together and separate. The mutation, found in several families from North America, Australia, and Belgium, impairs a variety of critical cell transport processes. In addition, neutropenia, a white blood cell disorder, was found to be inherited along with the disease, which has not been seen in CMT families before. The same protein function that is impaired by the mutation--the ability to bind a high-energy molecule called CTP--is also impaired by other CMT gene mutations, suggesting this may be a central pathway for a large class of peripheral neuropathies.

New Parkinson's Di

Contact: Marilee Reu
American Academy of Neurology

Page: 1 2

Related medicine news :

1. Late-breaking Digestive Disease Week news
2. Late-breaking clinical trials
3. Making science personal: Lilly Oncology to unveil 76 studies at ASCO 2007
4. Exercise science principles strengthen swallowing rehabilitation
5. Inaugural award honors collaborative team science
6. Key science Web sites buried in information avalanche
7. Computer scientist reveals the math and science behind blockbuster movies
8. The science behind a wrinkle-filler: Researchers discover for the first time how product works
9. Tobacco companies obstructed science, history professor says
10. Americans fear decline in US performance in math and science
11. Policy makers, networking agencies told to get their act together for nanoscience

Post Your Comments:

(Date:2/19/2020)... ... February 19, 2020 , ... MedTech ... Encouraged to Apply to Participate in 2020 Cohort , The Massachusetts Medical Device ... program is now accepting applications from startup founders and CEOs to participate in ...
(Date:2/19/2020)... ... February 19, 2020 , ... ... a CoolEvent for FDA-cleared CoolSculpting®, the world’s most popular non-invasive fat reduction treatment. ... 850 in the Halcyon Village Center in Alpharetta, Georgia. The CoolEvent will feature ...
(Date:2/15/2020)... ... ... It all started back in 2010, when Jennifer Martinez (Founder) was delighted ... was on to something special. The Heartsters have now become a circle of ... health condition or illness, a disability or just having a bad day. , ...
(Date:2/13/2020)... (PRWEB) , ... February 13, 2020 , ... ... non-profit and business sectors, committed to achieving health equity for all Americans will ... recommendations at a February 26th event at the National Press Club. , The ...
(Date:2/11/2020)... NEW YORK (PRWEB) , ... February 11, 2020 , ... ... of Radiology Benefit Management (RBM), but the service that truly raises us above our ... reviewer and medical director is a board-certified Radiologist with years of clinical experience. We ...
Breaking Medicine News(10 mins):
(Date:2/19/2020)... ... February 19, 2020 , ... ... data management, has released a new SnapGene integration. This integration ... a ‘Quick View’ of supported DNA files, the molecular biology community has ...
(Date:2/15/2020)... , ... February 14, 2020 , ... Dr. Ray Lopez, ... Haute Beauty Network. , The Haute Beauty Network, well known for its exclusive and ... foot and ankle and our newest addition to the Haute Beauty members-only network. , ...
(Date:2/14/2020)... , ... February 14, 2020 , ... Dignitana AB ... Dignitana, Inc ., has signed on to sponsor three signature events in 2020 with ... in the Susan G. Komen Race for the Cure® and MORE THAN PINK Walk® ...
Breaking Medicine Technology:
Cached News: