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Late-breaking science presented at 57th AAN Annual Meeting

sease Gene Mutation is Very Common in North Africa

The newest gene for Parkinson's disease, LRRK2, is proving to be a very common cause of familial PD. Recent studies have shown it is responsible for up to 6 percent of familial cases in North America and Europe. In this study, researchers found that 41 percent of autosomal dominant PD in North African patients were due to a single mutation in the gene, which is also the most common mutation in other populations. As has been seen in other populations, younger mutation carriers were less likely to be affected, indicating the existence of age-dependant penetrance for the gene mutation.

The late-breaking science will be presented during a poster session at 7:30 a.m. on Tuesday, April 12 in Hall A of the Miami Beach Convention Center. For abstract copies, please contact the AAN Press Room.


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Contact: Marilee Reu
mreu@aan.com
American Academy of Neurology
12-Apr-2005


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