HOME >> MEDICINE >> NEWS
Little evidence behind bronchodilator therapy for cystic fibrosis

Little evidence exists to support the widespread use of bronchodilators to treat children and adults with cystic fibrosis, according to a new systematic review of published research.

"Recurrent wheeze and breathlessness are common in people with cystic fibrosis, and bronchodilators are commonly prescribed," according to lead author Clare Halfhide, M.D., of the Royal Liverpool Children's Hospital in England. "Despite their wide-scale and often long-term use, there is limited objective evidence about their efficacy in cystic fibrosis."

The review appears in the current issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

Cystic fibrosis is a genetically inherited disease afflicting the lungs and the digestive system, the result of both parents passing on an abnormal gene. It is chronic, progressive and ultimately fatal.

Cystic fibrosis causes the exocrine glands, which produce sweat and mucus, to produce thick mucus that clogs the lungs, causing chronic respiratory difficulties. The mucus also obstructs pancreatic ducts, preventing digestive enzymes from reaching the intestines. Consequently, people with cystic fibrosis have difficulties breathing, absorbing nutrients and eliminating non-digested food.

The Cochrane review included 14 trials randomized controlled trials comprising 257 participants with cystic fibrosis.

Several trials compared inhaled bronchodilator drugs to placebo by looking at two common measures of lung function. Forced expiratory volume, or FEV1, represents the volume of air that can be forced out in one second after taking a deep breath. Peak expiratory flow rate represents how fast a person can exhale air.

Improvements occurred primarily in a sub
'"/>

Contact: Clare Halfhide
chalfhide@hotmail.com
Center for the Advancement of Health
25-Oct-2005


Page: 1 2 3

Related medicine news :

1. Little difference between human insulin and faster-acting drugs
2. Little change in suicidal thoughts, plans or attempts in US
3. Little evidence found for IVF as most effective infertility treatment
4. Little answers to worlds biggest problems
5. Majority of herb users dont follow evidence-based indications, researchers find
6. No evidence older women generate new eggs
7. Opportunistic chlamydia screening not underpinned by sound evidence
8. Drug safety recommendations lack scientific evidence
9. Study links attempted suicide with genetic evidence identified in previous suicide research
10. Fosrenol data show evidence of trends towards improved bone formation in CKD stage 5 patients
11. Mayo Clinic researchers find evidence for traumatic cause of carpal tunnel syndrome

Post Your Comments:
(Date:9/4/2015)... ... September 04, 2015 , ... Having access to a ... led to an increasing amount of unnecessary emergency room visits which affects hospitals’ abilities ... the country’s health bill. Fortunately, a solution to alleviate this problem has recently presented ...
(Date:9/4/2015)... ... 2015 , ... Lalonde Gordon ran a 44.64 seconds scorcher in the third ... men’s 400 meters final, with an impressive 44.89 seconds at the 2015 North American, ... Rica in August 2015. The 44.64 time is a new NACAC Championship record. ...
(Date:9/4/2015)... DC (PRWEB) , ... September 04, 2015 , ... ... they all pale in comparison to settlements under the Stark physician self-referral law. ... an upcoming Sept. 17 webinar from Atlantic Information Services, Inc. (AIS), will detail ...
(Date:9/4/2015)... NC (PRWEB) , ... September 04, 2015 , ... ... filtration products, has a Labor Day offer that cannot be passed up. ... stock up on necessary air and water filtration product replacements. Take advantage of ...
(Date:9/4/2015)... (PRWEB) , ... September 04, 2015 , ... Friday night, ... IL hosting Generation Rescue’s A Night of Hope event supporting families affected by autism, ... and Rowena and Joe Salas, joined together at the Oscar Swan Inn to support ...
Breaking Medicine News(10 mins):Health News:Telemedicine Platform DocChat Announces Launch Offering a Way for Patients to Consult Doctors and Receive Prescriptions 24/7 2Health News:Telemedicine Platform DocChat Announces Launch Offering a Way for Patients to Consult Doctors and Receive Prescriptions 24/7 3Health News:Lalonde Gordon’s Recipe Brings Home the Gold 2Health News:Lalonde Gordon’s Recipe Brings Home the Gold 3Health News:Sept. 17 Webinar to Offer Best Practices for Physician Contracts 2Health News:FiltersFast.com Wows with a Long Labor Day Weekend Shipping Offer 2Health News:Jenny McCarthy & Donnie Wahlberg Help Raise Over $200,000 For Generation Rescue’s ‘Night Of Hope’ Chicago Charity Event 2
(Date:9/3/2015)... NEW YORK , Sept. 3, 2015 About ... in dryness of eyes due to deficient tear production ... This syndrome is of two types: aqueous tear deficient ... deficient dry eye, lacrimal glands do not produce enough ... eye. Meibomian glands secrete lipids to slow tear evaporation ...
(Date:9/3/2015)... Sept. 3, 2015  WellCare Health Plans, Inc. (NYSE: ... , senior vice president and chief financial officer, is ... Healthcare Conference on Wednesday, September 9, 2015, at 9:25 ... webcast live. In addition, a replay of the webcast ... broadcast. Both the live broadcast and the replay will ...
(Date:9/3/2015)... and ALISO VIEJO, Calif. ... (NYSE: AGN ), a leading global pharmaceutical ... medical device company focused on developing ocular implants ... today announced that they have entered into an ... an all-cash transaction.  Under the terms of the ...
Breaking Medicine Technology:Global Dry Eye Syndrome Market 2015-2019 2Allergan to Acquire Glaucoma Treatment Company AqueSys to Add Minimally Invasive Implantable Shunt to Eye Care Offering 2Allergan to Acquire Glaucoma Treatment Company AqueSys to Add Minimally Invasive Implantable Shunt to Eye Care Offering 3Allergan to Acquire Glaucoma Treatment Company AqueSys to Add Minimally Invasive Implantable Shunt to Eye Care Offering 4Allergan to Acquire Glaucoma Treatment Company AqueSys to Add Minimally Invasive Implantable Shunt to Eye Care Offering 5Allergan to Acquire Glaucoma Treatment Company AqueSys to Add Minimally Invasive Implantable Shunt to Eye Care Offering 6
Cached News: