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Liver transplants can be successful in HIV patients with Hepatitis B

note that since liver transplants in HIV patients are relatively new, questions about several issues have been raised, such as the ideal timing in HIV-HBV or HIV-HCV (Hepatitis C) patients, the risk of HIV progression after transplant, and the risk of liver toxicity with HAART. They note that although the current study is small, its message is important, particularly with regard to the fact that many potential candidates die either while on the waiting list or while being evaluated for transplant. "A particular effort should be made to inform physicians caring for HIV patients of the possibility of liver transplantation in this patient population and the importance of a prompt referral to liver transplantation centers," the authors state. They also suggest that studies need to be conducted to determine factors that might indicate a poor prognosis in these patients. "In conclusion, liver transplantation for HIV patients is an emerging field with good preliminary results in HIV-HBV infected patients and pending results in evaluation of HIV-HCV patients," the authors state. They add that discussions among hepatologists, transplant physicians and HIV specialists need to take place regarding the best timing for liver transplantation and the choice of HAART in order to avoid the emergence of drug-resistant HBV.


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Contact: Amy Molnar
amolnar@wiley.com
John Wiley & Sons, Inc.
1-May-2006


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