HOME >> MEDICINE >> NEWS
Long-term safety results released for breast cancer drugs

Anastrozole is tolerated better than tamoxifen for the treatment of postmenopausal women with early-stage breast cancer after surgery, according to research published in the August issue of The Lancet Oncology. "Use of anastrozole led to a lower occurrence of adverse effects and serious adverse events and significantly fewer withdrawals from treatment than use of tamoxifen", explain the researchers.

The Arimidex, Tamoxifen, Alone or in Combination (ATAC) trial compared use of anastrozole with that of tamoxifen in more than 6000 postmenopausal women with breast cancer that had not spread to other parts of the body. The researchers now present data after more than 5 years of follow-up, which show that no new safety concerns have emerged. Overall, adverse events did not differ between the two groups, but significantly fewer patients in the anastrozole group than in the tamoxifen group had adverse events that were related to their treatment or caused them to withdraw from treatment.

The researchers also did a risk benefit analysis of the two drugs, which took into account both the chance that the patients would have a recurrence of their breast cancer and the side-effects caused by their treatment. The analysis showed that anastrozole had a significantly better risk benefit profile, and that this benefit was greatest at 12 years of treatment. The researchers conclude that their findings support the use of anastrozole rather than tamoxifen as the preferred initial treatment after surgery for these women.


'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
1-Aug-2006


Page: 1

Related medicine news :

1. Long-term treatment with VYVANSE, first prodrug stimulant, demonstrates significant efficacy in ADHD
2. Long-term anti-clotting therapy sweetens stenting outcomes in diabetic patients
3. Long-term aspirin use associated with reduced risk of dying in women
4. Long-term data on safety and effectiveness of antiobesity drugs needed
5. Long-term financial costs associated with prostate cancer treatment
6. Long-term effects of non-alcoholic fatty liver disease
7. Long-term outcomes for prostate cancer show IMRT Curative: 89 percent disease-free 8 years later
8. Long-term abstinence may resolve many of the neurocognitive deficits associated with alcoholism
9. Long-term ibuprofen regimen after brain injury worsens cognition in animal study
10. Media availability: Long-term survival of heart attack patients with shock
11. Long-term estrogen therapy linked to breast cancer risk

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/19/2020)... (PRWEB) , ... February 19, 2020 , ... ... MedTech Start Up Founders Encouraged to Apply to Participate in 2020 Cohort , ... MedTech IGNITE program is now accepting applications from startup founders and ...
(Date:2/19/2020)... (PRWEB) , ... February 19, 2020 , ... ... published, which expanded the scope of regulations and requirements that currently govern medical ... was three years, which extends until 25 May 2020. Major changes from the ...
(Date:2/19/2020)... , ... February 19, 2020 , ... ... and consistency of healthcare delivery, announced that it will participate in the ... Orlando, Florida. BPM+ Health will engage healthcare professionals and other stakeholders at HIMSS20 ...
(Date:2/19/2020)... ... 19, 2020 , ... Nvision Biomedical Technologies , a ... for lower extremities at the American College of Foot and Ankle Surgeons Annual ... Ti Stand-Alone Osteotomy Wedge Fixation System will lead Nvision's innovative showcase. The Trigon ...
(Date:2/19/2020)... Fla. (PRWEB) , ... February 19, 2020 , ... SEAL ... year as a result of healthcare-acquired infections (HAIs.) According to The Centers for Disease ... for is the large amount of screens that are now acting as an extension ...
Breaking Medicine News(10 mins):
(Date:2/19/2020)... ... February 19, 2020 , ... ... for research data management, has released a new SnapGene integration. ... features. With a ‘Quick View’ of supported DNA files, the molecular biology ...
(Date:2/19/2020)... ... February 19, 2020 , ... The Edvocate, ... colleges and universities for people with disabilities. , The Edvocate highlighted institutions ... disabilities succeed in higher education. AIC placed in the top ten with the ...
(Date:2/19/2020)... ... February 19, 2020 , ... ... provider organizations with the release of its annual GHX “Best 50” ... America’s premier hospitals for their ability to demonstrate improved operational performance and drive ...
Breaking Medicine Technology:
Cached News: