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Loss of stem cells correlates with premature aging in animal study

maturely, in one fell swoop. Essentially, these mice start their young adulthood with two strikes against them in terms of long-term tissue maintenance, and so, they subsequently age before their time.

With this new knowledge of how DNA repair, stem cells, and the aging process interconnect, Brown, first author Yaroslava Ruzankina, and Amma Asare are currently using this mouse model to discover compounds that preserve stem cells and may, consequentially, suppress aging.


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Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
6-Jun-2007


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