HOME >> MEDICINE >> NEWS
Lower doses of chemotherapy equally effective in most children

WINSTON-SALEM -- A pediatric oncologist at Brenner Children's Hospital hopes his latest research into treating a common childhood cancer will reduce the number of long-term side effects that survivors experience as they grow into adulthood. Allen Chauvenet, M.D., presented his findings today at the American Society of Pediatric Hematology/Oncology (ASPHO) annual meeting in Washington, D.C.

Chauvenet and his colleagues looked at the current chemotherapy prescribed for Acute Lymphblastic Leukemia (ALL), the most common childhood cancer diagnosed in the United States.

"While the cure rates for this cancer have dramatically improved over the years, many children have considerable long-term side effects, such as significant drops in IQ scores, growth failure and infertility," he said. "We wanted to identify patients whose cancer we could cure, while minimizing the long-term effects of the treatment."

Chauvenet and his colleagues used relatively limited amounts of chemotherapy for children identified as having an excellent chance of cure and monitored the group of 650 patients for about 12 years.

At the end of the study, the group discovered that 86.4 percent of patients were described as event-free survivors at the end of 10 years. And 95.9 percent were overall survivors at the end of the 10-year period. Event-free survivors were patients who had no relapses or second malignancies in the time frame. Overall survivors experienced one of those conditions, but were still living at the end of the study period.

"This showed us that using limited chemotherapy worked in a large number of cases with minimal complications," he said. "The next step would be to fine-tune the identification of those patients upfront so that long-term side effects could be avoided in as many patients as possible."

Chauvenet and his colleagues looked for factors that might predict which children would do well with less intensive chemotherapy drugs. Th
'"/>

Contact: Rae Bush
rbush@wfubmc.edu
336-716-6878
Wake Forest University Baptist Medical Center
16-May-2005


Page: 1 2

Related medicine news :

1. Lower mortality rates associated with hospitals that rank highest on quality of care indicators
2. Lowering body temperature could aid standard stroke treatment
3. Lower income means higher risk for heart disease
4. Lowering of blood pressure achieved through use of hashish-like drug
5. Lower literacy means poor health and poor health care access for older people
6. Lowering blood pressure doesnt prevent cognitive impairment, dementia
7. Lower levels of physical performance associated with increased risk of dementia in older adults
8. Lower doses of clot-busting drug safer for stroke patients
9. Lowering blood pressure more important than drug class in preventing kidney disease
10. Lowering resistance to insulin may delay or prevent onset of type 2 diabetes
11. Lower vaccination rates put children at risk

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... ... September 03, 2020 , ... The growing adoption of ... Fall 2020 Virtual Conference, a two-day virtual event for radiology professionals that will ... is the follow-up to AuntMinnie.com's successful virtual event in spring 2020, in which ...
(Date:9/1/2020)... ... September 01, 2020 , ... ... in Glendale. While the office will be the first to bear her ... tucks, buttock augmentation (Brazilian butt lift), as well as rhinoplasty, facial rejuvenation, and ...
(Date:8/31/2020)... ... August 31, 2020 , ... Cardiothoracic surgeons at ... engineers from Carnegie Mellon University (CMU) to develop a new heart monitoring device ... open heart surgery. , The AGH/CMU team was recently awarded a “Trailblazer” grant ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... ... cloud-based business management solution for chiropractors, announced today the launch of its integrated, ... professionals can start running their virtual practice in under 90 seconds. , ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to ... is donating 10 percent of each hotel room booked with a special new ... Chicagoland & Northwest Indiana (RMHC-CNI) , effective immediately. Donations will be applied to ...
Breaking Medicine News(10 mins):
(Date:8/27/2020)... ... August 27, 2020 , ... Trella ... Enquire, a leading provider of cloud CRM, marketing automation, and contact center solutions ... will involve the integration of Trella’s performance intelligence data and insights into Enquire’s ...
(Date:8/26/2020)... ... August 26, 2020 , ... ScripHessco has announced the ... infographic breaks down ways that chiropractors can help heal sports injuries and get ... “Athletes have an unusual amount of pressure and stress on their bodies, so ...
(Date:8/26/2020)... CITY, Tenn. (PRWEB) , ... August 26, 2020 ... ... both commercial and in-home air purification systems kill Coronavirus. While air purification technologies, ... of viruses including SARS and even Ebola, no air purification system has published ...
Breaking Medicine Technology:
Cached News: