HOME >> MEDICINE >> NEWS
Lung cancer risk reduced in female textile workers exposed to endotoxin

Long-term, high-level exposure to bacterial endotoxin-- a contaminant found in raw cotton fiber and cotton dust -- is associated with a 40 percent decrease in lung cancer risk among female Chinese textile workers, according to a new study in the March 7 Journal of the National Cancer Institute.

Since the 1970s, studies in the U.S. and abroad have reported a lower than average risk of lung cancer for textile workers. Additionally, studies have shown that workers in other occupations with high endotoxin exposure, such as dairy farmers, have reduced lung cancer risks as well. Although many researchers thought endotoxin might be associated with reduced risk of lung cancer, no previous studies had quantified the relationship between endotoxin exposure and lung cancer risk.

George Astrakianakis, Ph.D., of the University of Washington in Seattle, and his colleagues compared the endotoxin exposure of 628 female cotton textile workers in Shanghai who were diagnosed with lung cancer with a group of 3,184 female workers without lung cancer who were matched by age to the cancer patients. They estimated the workers' total endotoxin exposure in textile factories based on their measurements of cotton dust exposure, which varied depending on the workers' jobs and length of employment.

The risk of developing lung cancer decreased as workers were exposed to greater amounts of endotoxin over many years. Twenty years of exposure to endotoxin reduced the incidence of lung cancer to approximately 7.6 per 100,000, compared with 19.1 per 100,000 for the average Shanghai woman. The risk was lowest for women whose endotoxin exposure occurred early in their career.

How endotoxins could reduced lung cancer risk is unclear. "Potential anticarcinogenic effects of endotoxin are probably mediated by the innate and acquired immune systems, although the specific mechanisms have yet to be elucidated," the authors write.

The researchers considered s
'"/>

Contact: Liz Savage
elizabeth.savage@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
6-Mar-2007


Page: 1 2

Related medicine news :

1. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
2. Survival differences by race most apparent in advanced stages of breast cancer
3. Stomach cancer rate set to fall further 25 percent over next decade
4. MRI finds breast cancer before it becomes dangerous
5. Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
6. New cause of tamoxifen resistance in breast cancer cells discovered at Lombardi
7. Pathway links inflammation, angiogenesis and breast cancer
8. Using MRI for diagnosis could help prevent breast cancer progression
9. Electric fields have potential as a cancer treatment
10. Shining light on pancreatic cancer
11. Method shows promise for early detection of pancreatic cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/1/2020)... ... ... Feeding Matters , the first organization in the world dedicated to advancing the ... that the U.S. Centers for Disease Control and Prevention (CDC) has officially approved PFD ... U.S. International Classification of Diseases (ICD ) on October 1, 2021. ...
(Date:8/31/2020)... , ... August 31, 2020 , ... Just found out your dear friend has cancer? ... when your friend or family member shares their diagnosis. Once the shock wears off, the ... the wrong thing? What are the best ways to help? Words are failing me. I’m ...
(Date:8/31/2020)... ... August 31, 2020 , ... Smile Brands Inc., one of ... United States, today announced the grand opening of another affiliated Bright Now! ... enjoy convenient hours, a comfortable office, and full-service care at the new Beaumont ...
(Date:8/31/2020)... ... August 31, 2020 , ... Bonde Innovations, LLC, a venture-backed ... heart failure, today announced that the company has been awarded a Phase 1 ... National Heart, Lung, and Blood Institute of the National Institutes of Health (NIH). ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... ... The Nourished Group set out to continue helping the specialty-diet community connect ... discover new gluten-free products, get coupons, enter giveaways, chat with brands & watch ...
Breaking Medicine News(10 mins):
(Date:8/27/2020)... ... 27, 2020 , ... Bridge To A Cure Foundation announces the appointment of ... pediatric neuro-oncologist who serves on the Board of Directors at The Preston Robert Tisch ... School. , Internationally recognized, Dr. Friedman is a widely published author of more than ...
(Date:8/26/2020)... , ... August 26, 2020 , ... ... Chiropractic Care Helps Sports Injuries. The infographic breaks down ways that chiropractors can ... healthier recovery. , According to ScripHessco “Athletes have an unusual amount of pressure ...
(Date:8/26/2020)... ... August 26, 2020 , ... ... BioPharma Services, Laboratory Testing division, expands its technology footprint with the addition ... Cytometry platforms available. With industry-leading biomarker solutions, complemented with traditional ligand-binding assays ...
Breaking Medicine Technology:
Cached News: