HOME >> MEDICINE >> NEWS
Mayo Clinic Cancer Center on the forefront of the fight against multiple myeloma

ATLANTA -- Promising findings were reported today showing that the combination of thalidomide and dexamethasone (Thal/Dex) when used as initial therapy for multiple myeloma, slowed disease progression almost two-fold compared to dexamethasone alone. Mayo Clinic's S. Vincent Rajkumar, M.D., presented the results of the largest ever study looking at this treatment at the annual meeting of the American Society of Clinical Oncology.

The findings were the result of an international, multicenter, randomized, double-blind, placebo-controlled clinical trial. They come after years of study by Dr. Rajkumar, a hematologist/oncologist, and his colleagues, into the most effective treatments for multiple myeloma.

"We are happy to be able to report such positive results for this still incurable cancer," said Dr. Rajkumar. "Not only have we consistently shown that Thal/Dex reduces the amount of cancer cells in the bone marrow, but now we can state that primary therapy with this combination produces superior long-term results compared to dexamethasone alone."

An earlier Eastern Cooperative Oncology Group randomized study (www.jco.org/cgi/content/full/24/3/431) led by Dr. Rajkumar showed that a significantly larger proportion of patients with newly diagnosed multiple myeloma responded to the Thal/Dex combination compared to dexamethasone alone (63 percent versus 41 percent respectively). That study led to the Food and Drug Administration (FDA) granting accelerated approval two weeks ago for thalidomide use in treating newly diagnosed multiple myeloma.

In this most recent study, Dr. Rajkumar's team found that the average time to disease progression (increase in cancerous cells) was approximately eight months for patients taking dexamethasone alone, while patients on the Thal/Dex regimen had an average progression time exceeding 17 months. "The average progression time will likely increase,
'"/>


5-Jun-2006


Page: 1 2 3

Related medicine news :

1. Clinical data suggest potential versatility of ALIMTA-based regimens in lung cancer
2. Susan G. Komen for the Cure and American Society of Clinical Oncology partner in national initiative
3. Clinical review -- A psychological approach to the management of irritable bowel syndrome
4. NHLBI Asthma Clinical Research Networks and ALA ACRC Network to present at ATS 2007
5. New Mayo Clinic MRI technology enables noninvasive liver diagnoses
6. Clinical trial data for Perforomist Inhalation Solution presented at International ATS Conference
7. Elsevier launches the Clinics on ScienceDirect
8. Clinical guidelines for blood conservation during cardiac procedures developed
9. Clinical trial data for Perforomist Inhalation Solution to be presented at ATS on May 20, 2007
10. Mayo Clinic research in cardiovascular disease presented at Experimental Biology 2007
11. Mayo Clinic study finds heart transplant patients benefit from new approach to immunosuppression

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... CHICAGO (PRWEB) , ... August 31, 2020 , ... In ... Chicago West Loop is donating 10 percent of each hotel room booked with ... House Charities® of Chicagoland & Northwest Indiana (RMHC-CNI) , effective immediately. Donations will ...
(Date:8/31/2020)... Conn. (PRWEB) , ... August 31, 2020 , ... ... device intended to improve outcomes for patients with advanced heart failure, today announced ... (SBIR) grant in the amount of $555,358 from the National Heart, Lung, and ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... ... Founder & CEO Craig Mandeville was named an Entrepreneur Of The Year® 2020 ... program honors entrepreneurial business leaders whose ambitions deliver innovation, growth and prosperity as ...
(Date:8/28/2020)... RANCH, Calif. (PRWEB) , ... August 28, 2020 ... ... cover a one-year subscription to a customized Lighthouse Health & Wellness mobile ... generous support of this project. Motorola Solutions Foundation awards grants each year to ...
(Date:8/28/2020)... ... August 28, 2020 , ... Integrated Viral Protection ... first Florida school to deploy its breakthrough Mobile Biodefense Indoor Air Protection System that ... North Classical Academy plans to fully reopen equipped with the filtration system on September ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... ... Breast and ovarian cancers are common diseases that affect many women. According ... women per year) and 10% of ovarian cancers (about 2,000 women per year) result ... in the Women’s Excellence Genetic Testing Program. , Dr. Jonathan Zaidan, MD, FACOG, President ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... advisory guide, has named Cloudticity a Gold winner in the 15th Annual 2020 ... peer recogniti o ns from Network Products Guide honoring achievements of ...
(Date:8/27/2020)... Texas (PRWEB) , ... August 27, 2020 , ... Austin ... Texas – is pleased to announce Dr. David Szalay, DDS, MD, has joined the ... treat patients in the new Pflugerville office, which is scheduled to open this fall. ...
Breaking Medicine Technology:
Cached News: