f men in their 60s and up to 90 percent of men in their 70s and 80s. It is not related to the development of prostate cancer, although causes of BPH tissue growth inside the prostate later in life is unclear. Researchers believe that with age the prostate becomes more susceptible to the effects of hormones, including testosterone.

The most effective way to treat CKD is to care for and manage the underlying disease. "It has been shown that many patients with kidney disease respond to surgical treatments of BPH," says Dr. Rule. "There are also medications to relieve obstructions, by either shrinking the prostate gland or relaxing muscles that contribute to the obstruction."

The recent study surveyed 476 white men, ages 40-79, randomly selected from Olmsted County, Minn. Eventually, the researchers would like to see if similar findings are reproduced among general populations studied at other research centers. Dr. Jacobsen also suggests further research and testing to determine if treating BPH reverses the progression of kidney disease.

Ultimately, the researchers hope the results of the study will encourage both physicians and patients to consider BPH as a factor in kidney disease. "Men with diagnosed BPH may need to be screened to see if this condition is causing kidney damage," says Dr. Jacobsen.

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Contact: Lisa Lucier or Marissa Mulford
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
28-Jun-2005

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