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Mayo Clinic study could lead to safer pesticides

e of the enzyme. We cannot target the residue if we do not know where it lies. Now, we can examine the location of the residue in three-dimensional space using terascale computers.

"This work offers a structural basis for the possible design of pesticides that are toxic to insects, but not to humans. It demonstrates the benefits in the power of molecular biology that led to the discovery of the functionally important and pest-specific cysteine residue that was hidden in a sea of protein sequences originally reported in 2002," Dr. Pang says.


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Contact: Amy Reyes
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
12-Oct-2006


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