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Mayo Clinic study finds heart transplant patients benefit from new approach to immunosuppression

in 29 patients also greatly impaired the development of the proliferative changes found in transplant coronary artery disease.

"Based on our findings, patients should still receive calcineurin inhibitors as the primary immunosuppressant immediately after transplant, and the conversion to sirolimus must be gradual in order to prevent rejection," says Dr. Kushwaha. "Today, standard practice at Mayo Clinic is to consider converting all heart transplant patients from calcineurin inhibitors to sirolimus at six months post-transplant if there are no contraindications."


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Contact: Elizabeth Rice
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
26-Apr-2007


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