HOME >> MEDICINE >> NEWS
Medication may promote opening of arteries following stroke

A medication known as argatroban, when combined with another drug already used in the treatment of stroke patients, may help restore the flow of blood through blocked arteries, according to a preliminary study in the August issue of Archives of Neurology, one of the JAMA/Archives journals.

Ischemic stroke, the most common type of stroke, generally occurs when a blood clot lodges in an artery, blocking blood flow to the brain. Some patients with ischemic stroke are treated quickly with intravenous recombinant tissue plasminogen activator (rtPA), which works to help dissolve the clot and reopen the artery. However, some patients do not respond to rtPA alone, according to background information in the article. In animals, argatroban--which blocks the action of chemicals that clot the blood--has been shown to work with rtPA, increasing blood flow, speeding the opening of blood vessels and preventing recurring blockages. Argatroban is approved for use in patients with heart attacks to help prevent clots but has not been tested in human stroke victims.

Rebecca M. Sugg, M.D., University of TexasHouston Medical School, and colleagues evaluated the safety and efficacy of the drug combination in 15 stroke patients (10 men and five women, average age 61 years) who had blockages in the cerebral arteries, major blood vessels leading to the brain. Patients received the standard dose of rtPA intravenously an average of 118 minutes after their symptoms began, with the initial dose of the drug administered in one minute and the rest infused over the period of an hour. Within one hour of rtPA treatment (an average of 172 minutes after symptoms began), the patients received a large dose of argatroban followed by a continuous 48-hour infusion. Patients were watched closely for signs of excessive bleeding (hemorrhage), the most common risk associated with drugs that prevent clotting; all but one participant, who showed initial signs of hemorrhage, received
'"/>

Contact: Deborah Mann Lake
713-500-3030
JAMA and Archives Journals
14-Aug-2006


Page: 1 2

Related medicine news :

1. Medication does not appear to offer benefit for certain heart attack patients undergoing PCI
2. Medication errors affect childrens leukemia treatment
3. IOM Advisory: Preventing Medication Errors News Conference on July 20
4. Medication use linked to farmers injuries
5. Medication plus oral contraceptive may improve female pattern hair loss
6. Medication reduces risk of adverse events for patients with acute coronary syndromes undergoing PCI
7. Medications that lower blood pressure linked to reduced risk of Alzheimers disease
8. Medication shows modest benefit in reducing weight, improving HDL, triglyceride levels
9. Medication plus beta-blocker helps prevent shocks from implantable cardioverter defibrillator
10. Medications and cough syrups may cause cavities
11. Medication reduces risk of heart irregularities after cardiac surgery

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/23/2017)... ... March 23, 2017 , ... Inflow IQ & Inflownomics of Raleigh, NC ... on a solid foundation. As experts in dangerous situations the Inflow IQ team ... soon. Inflownomics deliver ripe, fresh, clean & refreshing knowledge systems that enhance life. ...
(Date:3/23/2017)... ... 2017 , ... On 2 March 2017, the United States ... Command’s Patriot Award. The award was presented by the USSOCOM Commander, General Raymond ... its significant and enduring support to the command. , Accepting the award ...
(Date:3/23/2017)... ... ... “Beyond and Back”: a true-life testimony of tragedy and the miraculous power ... Rose, a wife, mother and grandmother committed to sharing her many spiritual adventures which ... new book presents actual events in the life of her family, which validate her ...
(Date:3/23/2017)... ... March 23, 2017 , ... “The Trainer”: an ... published author, Scotty, a fiction writer with an active imagination and an enthusiasm for ... book follows the tale of Wild Bill Hart, who sat looking at the thirty-three ...
(Date:3/22/2017)... ... March 23, 2017 , ... Catalent Pharma Solutions, the ... and consumer health products, today announced that it had won the ‘Clinical Supply ... the Suntec Singapore International Exhibition & Convention Centre, Singapore. The award was presented ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... 2017 ReNeuron reported in December 2016 ... chronic stroke patients, despite not meeting the three-month time frame ... Action Research Arm Test (ARAT). As a result, the company ... clinical study in 2017. Beyond CTX, we expect safety and ... and Phase I data from its critical limb ischaemia (CLI) ...
(Date:3/22/2017)... -- ReportsnReports.com adds Global Vagus Nerve Stimulation ... global vagus nerve stimulation market analyst says one trend ... invasive VNS procedures. Few years ago, VNS procedures were ... high standards of healthcare infrastructure. ... Browse 30 Exhibits, ...
(Date:3/22/2017)... , March 22, 2017 Ampio ... the development of Ampion™, a low molecular weight ... today announced that it is re-issuing its previous release ... incorporate certain disclosures that are required under the ... below are these additional disclosures along with the ...
Breaking Medicine Technology:
Cached News: