HOME >> MEDICINE >> NEWS
Medication may promote opening of arteries following stroke

A medication known as argatroban, when combined with another drug already used in the treatment of stroke patients, may help restore the flow of blood through blocked arteries, according to a preliminary study in the August issue of Archives of Neurology, one of the JAMA/Archives journals.

Ischemic stroke, the most common type of stroke, generally occurs when a blood clot lodges in an artery, blocking blood flow to the brain. Some patients with ischemic stroke are treated quickly with intravenous recombinant tissue plasminogen activator (rtPA), which works to help dissolve the clot and reopen the artery. However, some patients do not respond to rtPA alone, according to background information in the article. In animals, argatroban--which blocks the action of chemicals that clot the blood--has been shown to work with rtPA, increasing blood flow, speeding the opening of blood vessels and preventing recurring blockages. Argatroban is approved for use in patients with heart attacks to help prevent clots but has not been tested in human stroke victims.

Rebecca M. Sugg, M.D., University of TexasHouston Medical School, and colleagues evaluated the safety and efficacy of the drug combination in 15 stroke patients (10 men and five women, average age 61 years) who had blockages in the cerebral arteries, major blood vessels leading to the brain. Patients received the standard dose of rtPA intravenously an average of 118 minutes after their symptoms began, with the initial dose of the drug administered in one minute and the rest infused over the period of an hour. Within one hour of rtPA treatment (an average of 172 minutes after symptoms began), the patients received a large dose of argatroban followed by a continuous 48-hour infusion. Patients were watched closely for signs of excessive bleeding (hemorrhage), the most common risk associated with drugs that prevent clotting; all but one participant, who showed initial signs of hemorrhage, received
'"/>

Contact: Deborah Mann Lake
713-500-3030
JAMA and Archives Journals
14-Aug-2006


Page: 1 2

Related medicine news :

1. Medication does not appear to offer benefit for certain heart attack patients undergoing PCI
2. Medication errors affect childrens leukemia treatment
3. IOM Advisory: Preventing Medication Errors News Conference on July 20
4. Medication use linked to farmers injuries
5. Medication plus oral contraceptive may improve female pattern hair loss
6. Medication reduces risk of adverse events for patients with acute coronary syndromes undergoing PCI
7. Medications that lower blood pressure linked to reduced risk of Alzheimers disease
8. Medication shows modest benefit in reducing weight, improving HDL, triglyceride levels
9. Medication plus beta-blocker helps prevent shocks from implantable cardioverter defibrillator
10. Medications and cough syrups may cause cavities
11. Medication reduces risk of heart irregularities after cardiac surgery

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/18/2017)... Thailand (PRWEB) , ... August 19, 2017 , ... ... Business, Tourism Authority of Thailand presided over the Amazing Thailand Health and Wellness ... in Thailand. , Mr. Noppadon Pakprot, Deputy Governor for Tourism Products and Business ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... For Immediate Release                Contact: Julian Teixeira, August 18, 2017                    202-478-8564 / jteixeira@thenc.org ... Advice from their Fathers , Contrary to a father’s ...
(Date:8/18/2017)... (PRWEB) , ... August 18, 2017 , ... ... “Vision & Hearing” campaign, advocating for active, healthy lifestyles and highlighting the importance ... for individuals with hearing impairments and shares the latest innovations in hearing aid ...
(Date:8/18/2017)... ... August 18, 2017 , ... Mediaplanet ... advocating for active, healthy lifestyles and highlighting the importance of proactive eye and ... impairments and shares the latest innovations in hearing aid technology. , In ...
(Date:8/18/2017)... , ... August 18, 2017 , ... The Dawn Johnson ... inaugurating a new charity drive to generate community support for efforts to educate the ... cures and treatments for all types of cancer. , Each day in America, ...
Breaking Medicine News(10 mins):
(Date:8/17/2017)... , Aug. 17, 2017 MJAC2017 , the ... Canna Broadcast Media, today reveals its leading lineup. ... Inc., a global cannabis innovator specializing in the development of ... the conference. MassRoots, Rambridge™ and The Green Organic Dutchman are ... and Namaste Vapes™ as silver sponsors. ...
(Date:8/15/2017)... Mich. , Aug. 15, 2017 Diplomat ... naloxone to Michigan residents. ... Flint retail pharmacy, G-3320 Beecher ... approved by the Food and Drug Administration, is intended ... extreme drowsiness, slowed breathing, and loss of consciousness. The ...
(Date:8/14/2017)... Israel , Aug. 15, 2017  BrainStorm ... adult stem cell technologies for neurodegenerative diseases, announced financial ... "We are in ... 3 trial to investigate NurOwn ® in ALS," ... Officer of BrainStorm. "We have agreements with Mass. General ...
Breaking Medicine Technology:
Cached News: