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Miniature implanted devices could treat epilepsy, glaucoma

WEST LAFAYETTE, Ind. - Purdue University researchers have developed new miniature devices designed to be implanted in the brain to predict and prevent epileptic seizures and a nanotech sensor for implantation in the eye to treat glaucoma.

Findings will be detailed in three research papers being presented at the Engineering in Medicine and Biology Society's Sciences and Technologies for Health conference from Aug. 23-26 in Lyon, France.

One research project focuses on a tiny transmitter three times the width of a human hair to be implanted below the scalp to detect the signs of an epileptic seizure before it occurs. The system will record neural signals relayed by electrodes in various points in the brain, said Pedro Irazoqui (pronounced Ear-a-THOkee), an assistant professor of biomedical engineering.

"When epileptics have a seizure, a particular part of the brain starts firing in a way that is abnormal," Irazoqui said. "Being able to record signals from several parts of the brain at the same time enables you to predict when a seizure is about to start, and then you can take steps to prevent it."

Data from the implanted transmitter will be picked up by an external receiver, also being developed by the Purdue researchers.

The most critical aspect of the research is creating a device that transmits a large amount of data at low power. The transmitter consumes 8.8 milliwatts, or about one-third as much power as other implantable transmitters while transmitting 10 times more data. Another key advantage is that the transmitter has the capacity to collect data specifically related to epileptic seizures from 1,000 channels, or locations in the brain, Irazoqui said.

"The fact that this circuit can deliver such a vast amount of data and, at the same time, be less power hungry than anything else that's out there is what makes this important," he said.

A paper about that work will be presented during the c
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Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University
7-Aug-2007


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