Molecular imaging may lead to earlier diagnosis of childhood respiratory virus

"Most pathologists look at thick sections of RSV in formaldehyde, but our 3D structures are more fluid and amorphous than the solid structures pathologists have observed," Santangelo said. "The more we know about how RSV really looks, the more we'll understand about its pathogenesis."

RSV is the most important cause of respiratory infection in young children worldwide, infecting virtually every child in the first few years of life. Immunity is feeble and fleeting, and repeated infections are the rule. One in every 100 or 200 infected infants requires hospitalization, usually for bronchiolitis. There is not yet an effective vaccine for RSV, and current anti-viral drugs are in their infancy in terms of efficacy, Santangelo noted.

Ultimately, researchers want to conduct in vivo testing, but must first adapt their molecular beacons technology for that purpose, Santangelo said. "In the nearer term, we hope to use molecular beacons to detect RSV in clinical samples like with those taken with a nasal swab. We might be able to detect RSV in its first day of incubation and make an early diagnosis,'' he added.

The researchers also hope their research will lead to development of a suite of anti-viral drugs for treating RSV and other viruses, including human influenza.


Contact: Jane Sanders
Georgia Institute of Technology Research News

Page: 1 2 3

Related medicine news :

1. Elsevier launches Molecular Oncology
2. Molecular marker may help identify pancreatic cancer, and possibly predict survival time
3. Molecular differences between early and advanced melanomas could provide new drug targets
4. Molecular structure reveals how botulinum toxin attaches to nerve cells
5. Molecular medicine comes to the rescue
6. Molecular switch may turn off immune cells that target HIV
7. The Molecular Profiling Institute, Inc. and IBM advance technology
8. Molecular Profiling Institute secures $7.5 million in Series B funding
9. Molecular studies in cancer of the colon
10. Molecular ballet unravels, links proteins so cell can direct own movement
11. Molecular testing in patients with rare cancer predicts response to Gleevec

Post Your Comments:

(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern ... Laude and his M.D from the David Geffen School of Medicine at UCLA. He ... Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program ...
(Date:6/25/2016)... ... , ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter ... bar too high can result in disappointment, perhaps even self-loathing. However, those who set ... , Research from PsychTests.com reveals that behind the tendency to set low ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
(Date:6/24/2016)... Fla. (PRWEB) , ... June 24, 2016 , ... Global ... Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this recognition ... Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this year’s ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain ... for a minimum wage raise to $12 an hour by 2020 and then adjusting it ... the lost value of the minimum wage, assure the wage floor does not erode again, ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on the ... announced that patient enrollment in its ongoing randomized ... has exceeded 50% of its 24-patient target. Capricor ... the third quarter of 2016, and to report ...
(Date:6/23/2016)... , , , WHEN: , , ... , , , LOCATION: , , , Online, with free registration ... PANELISTS:  , , , Frost & Sullivan,s Global Vice President of ... Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... witnessing an exceptional era. Several new demand spaces, such as innovative ...
(Date:6/23/2016)... 23, 2016 Revolutionary technology includes ... Oticon , industry leaders in advanced audiology and hearing ... Oticon Opn ™, the world,s first internet connected hearing ... IoT devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ... number of ,world firsts,: , TwinLink™ - ...
Breaking Medicine Technology:
Cached News: