HOME >> MEDICINE >> NEWS
Morphine and topical anaesthesia effective in treating procedural pain in newborn infants

Researchers at The Hospital for Sick Children (SickKids) have found that intravenous morphine used alone or with a topical anaesthetic (tetracaine) effectively reduced levels of pain in newborn infants undergoing insertion of central venous catheters (central lines). This research is reported in the February 15, 2006 issue of the journal JAMA.

About 10 to 15 per cent of newborns require prolonged hospitalization for conditions such as preterm birth, congenital defects and sepsis (a blood stream infection). As part of their medical care, these infants are often exposed to multiple invasive procedures that may be painful.

"It was not so long ago that infants routinely underwent painful procedures without the benefits of analgesia. Our previous studies showed that infants do feel extreme pain, that they remember this pain and that it affects their future pain responses," said Dr. Anna Taddio, the study's lead author and principal investigator, a SickKids scientist and pharmacist, and an assistant professor of Pharmacy at the University of Toronto.

"Within the last decade, the pendulum started to swing in the other direction, and pain relievers began to be used more liberally in infants. However, more information was needed about the benefits and risks of the different treatment options. We undertook this study to determine the most effective way to manage pain in infants undergoing central line placements and to delineate the side effects associated with their use," said Dr. Taddio.

The research team studied the relative efficacy and safety of a topical anaesthesia (tetracaine) and intravenous opioid analgesia (morphine), used alone or in combination, for management of pain in newborns undergoing insertion of a central venous catheter. Many hospitalized newborns require central lines for the administration of medication and nutrition. The randomized, double-blind, controlled trial included 132 ventilated newborns in the neonatal intensiv
'"/>

Contact: Laura Greer, Public Affairs
laura.greer@sickkids.ca
416-813-5046
University of Toronto
14-Feb-2006


Page: 1 2

Related medicine news :

1. Morphine kills pain -- not patients
2. Morphine and topical anesthesia found effective in treating pain in newborn infants
3. Morphine for chest pain increases death risk
4. UW study tests topical honey as a treatment for diabetic ulcers
5. Short-term topical corticosteroid use may offer relief for patients with acute form of psoriasis
6. Jefferson scientists find topical lubrication helps outcomes of coronary stent procedures
7. Diagnosis of rhinitis and atopical dermatitis
8. New topical pain cream reduces pain
9. Common incontinence drug could have an additional topical effect on the bladder itself
10. Awareness under anaesthesia-findings from research by University of Leicester professor
11. New treatment effective in counteracting cocaine-induced symptoms

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/21/2020)... ... May 21, 2020 , ... ... to Coordinating Clinical Research, CenterWatch eLearning , https://www.centerwatch.com/products/category/2764-elearning/product/472-the-crc-trainer , Wherever ... An Interactive Companion to the CRC’s Guide to Coordinating Clinical Research provides ...
(Date:5/21/2020)... ... May 21, 2020 , ... ... announces its first milestone to deliver over one million FDA-compliant face shields — ... Medical Face Shields meet the critical need for personal protective equipment (PPE) for ...
(Date:5/21/2020)... ... 2020 , ... Having the cushion of an already established ... gained ground with the inherited reputation of quality, innovation, and professionalism. The VITA ... effective way for the ingredients to become immediately available to the cells. This ...
(Date:5/21/2020)... ... 2020 , ... Friends of Lisa Campbell, announce that Lisa Campbell, candidate for ... Southeast Advocates (PPSEA). PPSEA educates and lobbies on behalf of women’s health ... reproductive health care. PPSEA educates and lobbies on behalf of women’s health and works ...
(Date:5/21/2020)... ... May 21, 2020 , ... ESO , the leading data and software ... of its 2020 ESO Fire Service Index . The Index looks at key ... first apparatus turnout time and travel time, the most common property types visited and ...
Breaking Medicine News(10 mins):
(Date:5/28/2020)... , ... May 28, 2020 , ... ... The Beryl Institute releases its latest white paper, Caring for our Children: A ... successful patient experience practices in pediatric settings and highlights key findings to help ...
(Date:5/27/2020)... ... ... , CARDIOLOGY, Passaic County, Dr. Anuj Shah , CHIROPRACTIC CARE, ... Dr. Mi Jo , Morris County, Dr. Derek Ferguson ... , FAMILY PRACTICE, Camden County, Dr. Krista King , Union ...
(Date:5/27/2020)... (PRWEB) , ... May 27, 2020 , ... Focus ... and cloud solutions, has announced it will once again sponsor the American Heart Association’s ... Good Champion. This will mark the third year the firm is sponsoring the AHA ...
Breaking Medicine Technology:
Cached News: