HOME >> MEDICINE >> NEWS
Mystery solved: Gold's power against autoimmune diseases defined

st one member of a class of metals, including a special form of gold, that all render MHC class II proteins inactive.

In subsequent experiments in cell culture, gold compounds were shown to render the immune system antigen presenting cells inactive, further strengthening this connection. These findings now give researches a mechanism of gold drug action that can be tested and explored directly in diseased tissues.

In 1890, a German doctor named Robert Koch found that gold effectively killed the bacteria that caused tuberculosis. In the 1930s, based on a widely held but probably erroneous connection at the time between tuberculosis and rheumatoid arthritis, a French doctor, Jacques Forestier, developed the use of gold drugs for the treatment of rheumatoid arthritis. Gold drugs have been used since then as an effective treatment for this and other autoimmune diseases such as Lupus, but treatment can take months for action and sometimes presents severe side effects which have diminished their use in recent years.

With this new understanding of how these metals function, it may now be possible to develop a new generation of gold-based drugs for treating rheumatoid arthritis and other autoimmune diseases that are more effective with fewer side effects.


'"/>

Contact: John Lacey
public_affairs@hms.harvard.edu
617-432-0442
Harvard Medical School
26-Feb-2006


Page: 1 2

Related medicine news :

1. Biologists learn structure of enzyme needed to power molecular motor
2. High-power MRI helps Mayo Clinic surgical team predict outcomes in unusual tumor cases
3. Pulsating gels could power tiny robots
4. Gladstone investigators identify a new protective action for the powerful anti-HIV factor, APOBEC3G
5. Leptin has powerful effect on reward center in the brain
6. Anticipation plays a powerful role in human memory, brain study finds
7. Anger and hostility speed up decline in lung power
8. Combination of three new, high-powered MRI systems at PENN is a first in the US
9. New guidelines offer power to prevent stroke
10. Brain power combined to form new $125M institute
11. Beta carotene slows decline in lung power associated with ageing

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Mystery solved Gold power against autoimmune diseases defined

(Date:7/1/2015)... ... July 01, 2015 , ... Did you know that ... Men’s Health Month, and we at Advanced Fertility Center of Texas (AFCT) would like ... , While infertility is often considered to be a “woman’s issue,” male fertility ...
(Date:7/1/2015)... (PRWEB) , ... July 01, 2015 , ... Convoy ... a community celebration in the Twin Cities on Saturday, August 1, at Spring Lake ... Cities community will provide more than $1 million worth of goods and services including ...
(Date:7/1/2015)... , ... July 01, 2015 , ... Scoliosis is a disorder in which the normally ... Foundation, it affects 2 to 3 percent of the population, or an estimated 6 to ... develops in children between the ages of 10 and 15. Most types of scoliosis are ...
(Date:7/1/2015)... ... 01, 2015 , ... A Priority Setting Partnership put in ... list they hope will guide future mesothelioma research. Surviving Mesothelioma has just posted ... , More than 450 mesothelioma patients, caregivers, and healthcare professionals answer the ...
(Date:7/1/2015)... ... July 01, 2015 , ... B. E. Smith, the only full-service ... national chief nursing officer recruitment for Capital Health in Pennington, ... B. E. Smith has recently placed more than 1,000 healthcare executives into organizations. ...
Breaking Medicine News(10 mins):Health News:Male Fertility: Improve Testosterone and Fertility With Natural Approaches 2Health News:Male Fertility: Improve Testosterone and Fertility With Natural Approaches 3Health News:Male Fertility: Improve Testosterone and Fertility With Natural Approaches 4Health News:Convoy of Hope Hosts Community Event in the Twin Cities 2Health News:Scoliosis: A Guide for Parents from Orthopedic Surgeon Dr. Fabien Bitan 2Health News:Scoliosis: A Guide for Parents from Orthopedic Surgeon Dr. Fabien Bitan 3Health News:Scoliosis: A Guide for Parents from Orthopedic Surgeon Dr. Fabien Bitan 4Health News:New Report Identifies Top 10 Mesothelioma Research Priorities, According to Surviving Mesothelioma 2Health News:Capital Health Retains B. E. Smith to Recruit New Chief Nursing Officer 2Health News:Capital Health Retains B. E. Smith to Recruit New Chief Nursing Officer 3
(Date:7/1/2015)... 1, 2015 Eli Lilly and Company (NYSE: ... quarter of 2015 on Thursday, July 23, 2015. Lilly will ... investment community and media to further detail the company,s financial ... a.m. EDT. Investors, media and the general public can access ... that will be posted on Lilly,s website at www.lilly.com ...
(Date:7/1/2015)... 1, 2015 According to a ... by Product (Natural & Synthetic, Fibrin, Collagen, Gelatin, Cyanoacrylate, ... - Global Forecast to 2020", published by MarketsandMarkets, the ... reach $2.64 Billion by 2020, growing at a CAGR ... Browse 119 market T ables ...
(Date:7/1/2015)... FT LAUDERDALE, Florida , July 1, 2015 ... developer, manufacturer and marketer of innovative medical devices for the ... 2015, it prevailed in a final opposition appeal hearing in ... 341 482 - STENT HAVING HELICAL ELEMENTS (,482). The ,482 ... EPO and has been upheld as a valid patent in ...
Breaking Medicine Technology:Lilly Confirms Date and Conference Call for Second-Quarter 2015 Financial Results Announcement 2Surgical Sealants and Adhesives Market Worth $2.64 Billion by 2020 2Surgical Sealants and Adhesives Market Worth $2.64 Billion by 2020 3Surgical Sealants and Adhesives Market Worth $2.64 Billion by 2020 4OrbusNeich Announces Favorable Ruling from the European Patent Office and Initiation of Litigation Against Terumo Corporation 2
Cached News: