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NHLBI awards 12 Women's Health Initiative contracts

n Effects of Genes in the Inflammatory Pathway and Dietary, Supplement, and Medication Exposures on General Cancer Risk, Wake Forest University School of Medicine, Winston-Salem, NC, Jianfeng Xu, M.D., Dr. P.H. The study seeks to identify genetic variants in genes involved in inflammation and immunity which are associated with the risk of cancer (breast, colon and rectum, and lung) in European Americans and African Americans. The research team will test associations between dietary, supplement and non steroidal anti-inflammatory use (NSAID) with inflammatory markers and risk of overall cancer. They will then study interaction effects of genetic variants with dietary, supplement, and NSAID exposure on cancer risk.

The NHLBI intends to fund a second round of studies using biological specimens from the WHI in 2008.

WHO: Dr. Jacques Rossouw, WHI project officer, is available to comment on these awards and the NHLBI's interest in maximizing the scientific yield from this landmark study.


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Contact: NHLBI Communications Office
nhlbi_news@nhlbi.nih.gov
301-496-4236
NIH/National Heart, Lung, and Blood Institute
29-Jan-2007


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