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NHLBI research highlights at American Heart Association's scientific sessions

At this year's American Heart Association's Scientific Sessions in Dallas, scientists supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health will present the latest research findings, including studies on women and heart disease, the extent of metabolic syndrome among African Americans in the Jackson Heart Study, and the impact of sodium reduction on the risk of cardiovascular disease.

Note that NHLBI will be issuing a separate release on a late breaking clinical trial presentation on November 15 on "The Effects of Carbohydrate, Protein, and Fat Intake on Cardiovascular Risk Factors: Main Results from the OmniHeart Feeding Study."

News stories are embargoed until papers are presented or a news conference or poster session begins. To reach NHLBI spokespeople, call the NHLBI Communications Office at 301-496-4236.

*Postmenopausal women with higher levels of male sex hormones levels have greater prevalence of coronary artery disease. (Embargoed until 4:45 p.m. Central Time (5:45 p.m. ET), Tuesday, November 15) The relationship between male sex hormones called androgens and atherosclerosis in women is poorly understood. Some studies have found an increased risk of coronary artery disease in women who have high levels of androgen, such as those who have polycystic ovary syndrome. Scientists with the Women's Ischemia Syndrome Evaluation (WISE) study analyzed blood hormone levels of 400 women (296 postmenopausal and 104 premenopausal) undergoing coronary angiography for suspected myocardial ischemia, a heart condition characterized by reduced blood flow. Hormones measured included estradiol, estrone, FSH, LH, free testosterone, sex-hormone binding globulin, androstenedione, and DHEA-S. Glucose and insulin were also measured. The investigators found that among postmenopausal women, higher levels of free testosterone and androstenedione are associated with greater coronary artery disease as sh
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Contact: NHLBI Communications Office
nhlbi_news@nhlbi.nih.gov
301-496-4236
NIH/National Heart, Lung, and Blood Institute
15-Nov-2005


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