HOME >> MEDICINE >> NEWS
NIAID launches first Phase II trial of a 'global' HIV/AIDS vaccine

A novel vaccine targeted to multiple HIV subtypes found worldwide has moved into the second phase of clinical testing, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today. The study investigators plan to enroll a total of 480 participants at sites in Africa, North America, South America and the Caribbean to test the safety and immune response to the vaccine.

The experimental vaccine was developed by scientists at NIAID's Dale and Betty Bumpers Vaccine Research Center (VRC) and is being studied in the HIV Vaccine Trials Network (HVTN), a clinical research collaboration funded by NIAID's Division of AIDS (DAIDS).

"This trial marks an important step in the advancement toward an AIDS vaccine. The rapid development of this candidate vaccine--less than five years since the launch of the VRC--underscores our commitment to hasten the day when we have an effective AIDS vaccine," says NIAID Director Anthony S. Fauci, M.D.

The unique vaccine combines synthetically modified elements of four HIV genes found in subtypes A, B and C of the virus--the subtypes commonly found in Africa, the Americas, Europe and parts of Asia. These subtypes represent about 85 percent of HIV infections worldwide.

"This is the first Phase II study of a vaccine candidate that is broadly relevant to the global AIDS pandemic because it combines components of HIV strains found throughout the world," says VRC Director Gary Nabel, M.D., Ph.D. "We look forward to working with our partners in the United States and abroad as we take this vaccine into the next phase of clinical evaluation."

The trial, known as HVTN 204, is being coordinated with two other planned clinical studies, an unprecedented collaboration among researchers in three clinical trial networks and NIAID. The International AIDS Vaccine Initiative plans to conduct a Phase I study of the VRC vaccine at sites in Kenya and Rwand
'"/>

Contact: NIAID News Office
niaidnews@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
11-Oct-2005


Page: 1 2 3 4

Related medicine news :

1. NIAID releases MDR/XDR Tuberculosis research agenda
2. NIAID DNA vaccine for H5N1 avian influenza enters human trial
3. NIAID media availability: Examining genetic variability of malaria parasite offers insight
4. NIAID awards $4 million to develop anti-radiation treatments
5. Partnership between NIAID and Sequella yields promising new TB drug for clinical testing
6. NIAID announces leadership for newly restructured HIV/AIDS clinical trials networks
7. NIAID study finds higher dose of flu vaccine improves immune response in the elderly
8. NIAID media availability: New study describes key protein from highly pathogenic H5N1 avian flu virus and how it might mutate
9. NIAID media availability: Understanding influenza infection
10. NIAID researchers show how promising TB drug works
11. NIAID awards $47 million to develop medical countermeasures against radiological, nuclear threats

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/9/2018)... ... November 09, 2018 , ... ... specializes in the treatment of autism and other developmental disabilities, is pleased to ... effort to address the service gap and alarming rise in Autism Spectrum Disorder ...
(Date:11/9/2018)... ... November 08, 2018 , ... ... Caring Transitions Ann Arbor. , Caring Transitions’ specially-trained team can handle organizing, packing, ... market. Caring Transitions specializes in assisting seniors, but their services are great for ...
(Date:11/9/2018)... ... November 08, 2018 , ... Dr. ... to provide advanced skin rejuvenation with NovaThreads® , a non-surgical alternative to ... with surgical sutures made of polydioxanone (PDO), a fully-dissolvable thread used in cardio-thoracic ...
(Date:11/8/2018)... ANGELES (PRWEB) , ... November 08, 2018 , ... For ... return from war. They often face immense challenges as they transition to civilian life, ... occasion to honor their service and support solutions that can improve their lives. The ...
(Date:11/8/2018)... LEHI, Utah (PRWEB) , ... November 08, 2018 , ... ... of Top Workplaces. , The 2018 list is compiled solely on employee feedback ... including alignment, execution, and connection, just to name a few. , “We strive to ...
Breaking Medicine News(10 mins):
(Date:11/8/2018)... SPRINGS, Texas (PRWEB) , ... November 08, 2018 ... ... Pueblo, Colorado has selected its patient electronic signatures and eForms solution . ... has been designated as its region’s first certified Stroke Center, has deployed this ...
(Date:11/8/2018)... THOUSAND OAKS, Calif. (PRWEB) , ... November 08, ... ... to announce the formation of a partnership in which Implant Direct will provide ... Dental consists of 1,400 supported doctors working in more than 875 offices in ...
(Date:11/8/2018)... ... November 08, 2018 , ... ... and analytics solution, today announced the results of a new survey on data ... CIOs and other senior healthcare IT leaders. Overall, it found few organizations have ...
Breaking Medicine Technology:
Cached News: