HOME >> MEDICINE >> NEWS
NIH scientists target future pandemic strains of H5N1 avian influenza

Preparing vaccines and therapeutics that target a future mutant strain of H5N1 influenza virus sounds like science fiction, but it may be possible, according to a team of scientists at the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), and a collaborator at Emory University School of Medicine. Success hinges on anticipating and predicting the crucial mutations that would help the virus spread easily from person to person.

Led by Gary Nabel, M.D., Ph.D., director of the NIAIDs Dale and Betty Bumpers Vaccine Research Center (VRC), the team is reporting in the August 10, 2007 issue of the journal Science that they have developed a strategy to generate vaccines and therapeutic antibodies that could target predicted H5N1 mutants before these viruses evolve naturally. This advance was made possible by creating mutations in the region of the H5N1 hemagglutinin (HA) protein that directs the virus to bird or human cells and eliciting antibodies to it.

What Dr. Nabel and his colleagues have discovered will help to prepare for a future threat, says NIH Director Elias A. Zerhouni, M.D. While nobody knows if and when H5N1 will jump from birds to humans, they have come up with a way to anticipate how that jump might occur and ways to respond to it.

Now we can begin, preemptively, to consider the design of potential new vaccines and therapeutic antibodies to treat people who may someday be infected with future emerging avian influenza virus mutants, says NIAID Director Anthony S. Fauci, M.D. This research could possibly help to contain a pandemic early on.

Making a vaccine against an existing strain of H5N1 or any other type of influenza virus is relatively routine. Typically, samples of existing influenza virus strains are isolated and then grown inside eggs or in cell cultures. The virus is then collected, inactivated, purified and added to the other components o
'"/>

Contact: Jason Socrates Bardi
jbardi@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
9-Aug-2007


Page: 1 2 3

Related medicine news :

1. Barrow scientists make headlines for their research on fixational eye movements
2. UD scientists invent novel hydrogels for repairing, regenerating human tissue
3. UK scientists set their sights on cure for AMD
4. Fat protein cuts blood vessel inflammation, may help heart, Jefferson scientists find
5. Smart mice teach scientists about learning process, brain disorders
6. Why predicting the next influenza pandemic is difficult and how scientists can best prepare
7. Sex and prenatal hormone exposure affect cognitive performance, Yerkes scientists find
8. AACR awards minority and other underrepresented scientists
9. Jefferson scientists find that plavix appears to be safe during and after heart bypass
10. Jefferson scientists find that drug-eluting stents are disappointing in bypass grafts -- sometimes
11. Forsyth scientists wiping out tooth decay through school-based cavities prevention program

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: NIH scientists target future pandemic strains avian influenza

(Date:12/20/2014)... a distinguished special dress supplier, has just done something ... cut prices to all its prom dresses already, offering ... Many of the hottest styles are sold here like ... more. , A spokesman for MissyDress says, “The great ... prom dresses or sweetheart chiffon prom dresses, you will ...
(Date:12/20/2014)... December 20, 2014 The print component ... with a distribution of approximately 160,000 copies and an ... nationally through a vast social media strategy and across ... To explore the digital version of the campaign, ... exclusive interview with the ladies of CTV’s The Social. ...
(Date:12/20/2014)... York, New York (PRWEB) December 20, 2014 ... continue to move forward in U.S. courts, ... new study which suggests that children treated with ... a hormone linked to breast development and lactation. ... looked at 34 children and adolescents who began ...
(Date:12/20/2014)... Xarelto bleeding lawsuits filed by ... bleeding and other serious side effects will be consolidated ... for coordinated pretrial proceedings, Wright & Schulte LLC reports. ... an order Friday to transfer 21 Xarelto lawsuits and ... courts to the Louisiana district court for coordination by ...
(Date:12/19/2014)... (PRWEB) December 20, 2014 It’s very easy ... is something that is put to the wayside until Christmas ... still have that travel “itch” and that burning desire to ... accommodates families on their journey to Telluride with a no-fuss, ... visitors to and from the resort, and ensure that all ...
Breaking Medicine News(10 mins):Health News:MissyDress: The Prices of Prom Dresses Just Reduced 2Health News:The ladies of The Social urge Canadian women to put themselves first over the holiday season and into the new year in Mediaplanet’s “Women’s Health” campaign 2Health News:Risperdal Lawsuit News: Bernstein Liebhard LLP Notes Publication of Study Suggesting Medication May Raise Prolactin Levels in Children 2Health News:Risperdal Lawsuit News: Bernstein Liebhard LLP Notes Publication of Study Suggesting Medication May Raise Prolactin Levels in Children 3Health News:Risperdal Lawsuit News: Bernstein Liebhard LLP Notes Publication of Study Suggesting Medication May Raise Prolactin Levels in Children 4Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 2Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 3Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 4Health News:Days Inn Montrose Colorado Delivers Last Minute Holiday Season Ski Getaway Accommodations 2
(Date:12/19/2014)... NEW YORK , Dec. 18, 2014 ... meals, addressing hearing health was forgotten. But Audicus ... resolve to hear better this new year. ... condition facing the aging population, though it is often ... one in four has a hearing aid, mainly due ...
(Date:12/19/2014)... INC. (NYSE: RMD ) today announced that it ... on Thursday, January 22, 2015, after the New York Stock ... be issued after 1:00 p.m. US Pacific Time and the ... future outlook. The earnings call is scheduled to ... webcast of the call can be accessed on ResMed,s Investor ...
(Date:12/19/2014)... membrane market has witnessed robust development with the growth pace ... later starter. In 2012, the size of China ... the proportion worldwide soaring to 16.3%. It is projected that ... its growth rate by around 20% in the upcoming years ... RMB25 billion. An integrated membrane industrial system has ...
Breaking Medicine Technology:Audicus Will Help People Resolve to Hear Better in 2015 2ResMed To Announce Second Quarter 2015 Results 2Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 2Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 3
Cached News: