NY-Presbyterian Hospital/Columbia University Medical Center doctors present at 2007 A...( lowing radical prostatectomy (RP) is an...),Health

lowing radical prostatectomy (RP) is an independent predictor of disease-free survival (DFS). However, the past 15 years have seen improvements in surgical and pathological techniques that may have altered the significance of positive surgical margins in prostate cancer. Thus, the researchers sought to determine if the predictive contribution of positive surgical margins on DFS has changed over the past 15 years. After performing an analysis of the Columbia Urologic Oncology Database, researchers found that the presence of +SM remains a significant independent predictor of DFS with no change in its predictive abilities. Thus, the presence of a +SM in the contemporary era is no less a significant outcome predictor than before the recent advancements in surgical and pathological techniques.

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Prostate Volume and Pathologic Prostate Cancer [1885]
Authors: Mitchell C. Benson, M.D., James M. McKiernan, M.D., Erik T. Goluboff, M.D., et al.

The relationship between prostate volume and prostate cancer parameters found at radical prostatectomy (RP) has yet to be fully elucidated. This study was designed to investigate these relationships, specifically the effect of prostate volume on biopsy and pathologic Gleason sum discordance. The study found that patients with large prostates are more likely to have lower Gleason sum, locally confined and less aggressive pathologic disease and subsequently were more often down-graded from biopsy to pathologic sampling.

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Experts Available for Commentary on Breaking News and
Other Stories at AUA Conference

NewYork-Presbyterian/Columbia experts are available for commentary on the following topics and breaking news (see AUA Press Kit for specifics) at the 2007 American Urological Association (AUA) meeting in Anaheim:

• Changes in the diagnosis and treatment of prostate cancer
• Statins and urology
• Tissue engineering and urology
• Erectile d
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Contact: Bryan Dotson
brd9005@nyp.org
212-305-5587
New York- Presbyterian Hospital/Columbia University Medical Center
23-May-2007


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