HOME >> MEDICINE >> NEWS
Nanoparticles offer new hope for detection and treatment

Specially designed nanoparticles can reveal tiny cancerous tumors that are invisible by ordinary means of detection, according to a study by researchers at Washington University School of Medicine in St. Louis.

The researchers demonstrated that very small human melanoma tumors growing in mice--indiscernible from the surrounding tissue by direct MRI scan--could be "lit up" and easily located as soon as 30 minutes after the mice were injected with the nanoparticles.

Because nanoparticles can be engineered to carry a variety of substances, they also may be able to deliver cancer-fighting drugs to malignant tumors as effectively as they carry the imaging materials that spotlight cancerous growth.

"One of the best advantages of the particles is that we designed them to detect tumors using the same MRI equipment that is in standard use for heart or brain scans," says senior author Gregory Lanza, M.D., Ph.D., associate professor of medicine. "We believe the technology is very close to being useful in a hospital setting."

Lanza and his colleague Samuel Wickline, M.D., professor of medicine, are co-inventors of this nanoparticle technology. The effectiveness of the nanoparticles in diagnosis and therapy in humans will be tested in clinical trials in about one and a half to two years.

The spherical nanoparticles are a few thousand times smaller than the dot above this "i," yet each can carry about 100,000 molecules of the metal used to provide contrast in MRI images. This creates a high density of contrast agent, and when the particles bind to a specific area, that site glows brightly in MRI scans.

In this study, MRI scans picked up tumors that were only a couple of millimeters (about one twenty-fifth of an inch) wide.

Small, rapidly growing tumors cause growth of new blood vessels, which feed the tumors. To get the particles to bind to tumors, the researchers equipped them with tiny "hooks" that link o
'"/>

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine
22-Apr-2005


Page: 1 2 3

Related medicine news :

1. Nanoparticles can track cells deep within living organisms
2. Nanoparticles carry cancer-killing drugs into tumor cells
3. Hormone therapy offers new hope for ovarian cancer patients
4. TB test offers patients quicker and easier diagnosis
5. Panel offers guidelines on skin reactions to new class of cancer drugs
6. Supersize me mice research offers grim warning for Americas fast food consumers
7. Developments in tissue engineering offer new sources for stem cell treatments
8. Targeted nanoparticles incorporating siRNA offer promise for cancer treatment
9. New treatment offers relief from chronic back pain
10. Commonly used drug offers promise for premature babies
11. Vitamin D supplements may offer cheap and effective immune system boost against TB

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Nanoparticles offer new hope for detection and treatment

(Date:7/31/2014)... In its latest blog post, Best Drug Rehabilitation ... close by during a stay in rehab can make a ... is focusing on nine secrets that addicts don’t want others ... can spot an addict from a mile away, and totally ... Rehabilitation’s CEO Per Wickstrom . “However, take it from ...
(Date:7/31/2014)... 31, 2014 In its latest blog post, ... believes that having family close by during a stay in ... the process is successful, is looking at 11 drug addiction ... should be. , “While some kids learn a ... health class, the coverage is typically woefully inadequate,” commented Best ...
(Date:7/31/2014)... 31, 2014 USHIO America’s Solid ... and general lighting marketplaces, today announced the launch ... will allow users to transform existing, inefficient lamp-based ... minutes. , USHIO America’s Uphoria LED downlight retrofit ... cans, allowing the user to upgrade old incandescent ...
(Date:7/31/2014)... In its latest blog post, Best Drug Rehabilitation ... close by during a stay in rehab can make a ... is looking at 10 tips to help drug or alcohol ... a lifelong process, and one that former addicts and those ... commented Best Drug Rehabilitation’s CEO Per Wickstrom . ...
(Date:7/31/2014)... City, NY (PRWEB) July 31, 2014 ... chocolate , will be available in New York's favorite ... in August. BRC is known for their commitment to ... Associated Press. , Chocolatto® is the new sensation from ... hot chocolate ! A delicious highly popular Italian dessert ...
Breaking Medicine News(10 mins):Health News:Latest Best Drug Rehabilitation Blog Posts Focuses on Nine Secrets Addicts Don’t Want Others to Know 2Health News:Latest Best Drug Rehabilitation Blog Posts Focuses on Nine Secrets Addicts Don’t Want Others to Know 3Health News:New Best Drug Rehabilitation Blog Posts Looks at 11 Drug Addiction Facts they Don’t Teach in School 2Health News:USHIO America Introduces Uphoria™ LED Downlight Retrofit Kits 2Health News:New Best Drug Rehabilitation Blog Posts Looks at 10 Tips for Coping After Drug or Alcohol Rehab 2Health News:Dolce Vite Chocolatto® - World's Best Thick Dark Italian Hot Chocolate Now Available at NYC's Favorite Cafe Brooklyn Roasting Company 2
(Date:7/31/2014)... De Pfizer Clinical Research Unit (PCRU) heeft de lancering ... komaf voor medewerking aan klinisch onderzoek. De in ... twee onderzoekseenheden van Pfizer , een multinationaal farmaceutisch ... ontdekking en ontwikkeling van nieuwe medicijnen. Om onderzoeksprojecten te ... vrouwen van Japanse komaf – leeftijd 18 tot 55 ...
(Date:7/30/2014)... , July 30, 2014  There is still ... organization,s success. The 10th Annual Institute for Supply ... for Excellence in Supply Management is open for ... the understanding and importance of supply management by ... and best supply management practices.  Entries are due ...
(Date:7/30/2014)... ANN ARBOR, Mich. , July 30, 2014 ... FY2015 first quarter (ending June 27, 2014) financial results on ... results will be released after the close of the market ... to discuss the results at 4:30 p.m. EDT on the ... Richard Kurtz (CEO and Director), Rob Risser ...
Breaking Medicine Technology:Gezonde vrijwilligers van Japanse komaf gezocht voor deelname aan Fase I klinisch onderzoek 2Institute for Supply Management, Michigan State University to recognize companies with excellent supply management practices 2Advanced Photonix to Webcast Fiscal 2015 First Quarter Earnings 2
Cached News: