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New allergy vaccine provides long-lasting hay fever relief after just 6 weeks of shots

make too much IgE antibody when exposed to inhaled allergens.

Additionally, the vaccine may activate specialized immune cells known as "dendritic cells" that serve as peacekeepers, maintaining balance by keeping inflammation in check over the long term and breaking an otherwise self-sustaining allergic cycle Creticos calls "Th2 orchestrated allergic inflammation."

"We are turning off an inappropriate or abnormal allergic response and returning the body to normalcy," says Creticos. "Our hope is that we can one day provide a long-term cure for hay fever and other chronic inflammatory diseases."


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Contact: Jeff Ventura
jventur4@jhmi.edu
410-955-7832
Johns Hopkins Medical Institutions
4-Oct-2006


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