HOME >> MEDICINE >> NEWS
New analysis supports starting with VFEND for life-threatening fungal infections

NEW YORK, October 25, 2005 A new analysis of treatment procedures for the potentially deadly fungal infection invasive aspergillosis suggests that making the right treatment decision as soon as possible after diagnosis may be crucial to survival.

The retrospective analysis, published in the Nov. 15 issue of Clinical Infectious Diseases, showed that patients who initially received Pfizer's antifungal agent VFEND (voriconazole) were more likely to survive than patients who initially received amphotericin B deoxycholate. The analysis also showed that patients who started on VFEND were less likely to need salvage therapy than those on amphotericin B. Salvage therapy is treatment given after the infection has not responded to the initial treatment or if the patient cannot tolerate the initial medicine.

Invasive aspergillosis is a severe pulmonary infection that can occur in patients with weakened immune systems. The fatality rate for invasive aspergillosis is estimated to be 58 percent, but approaches 90 to 100 percent in patients whose infection has spread beyond the primary site.

"These high mortality rates for invasive aspergillosis underscore the importance of initial treatment for this often fatal infection," said Dr. Thomas F. Patterson, lead author of the analysis and professor of medicine at the University of Texas Health Science Center at San Antonio. "Our analysis demonstrates that voriconazole's efficacy and tolerability make it an important choice for first-line therapy."

About The Study

The Global Comparative Aspergillosis Study (GCAS) led to VFEND's 2002 approval for the first-line treatment of invasive aspergillosis and was the basis for this newly published analysis. In that study, 144 patients with confirmed or probable invasive aspergillosis were started on VFEND and 133 were started on amphotericin B. If the disease progressed or the patient was unable to tolerate initial therapy, treatment could be chang
'"/>

Contact: Jeanne Traflet
jeanne.traflet@pfizer.com
212-733-0127
Edelman Public Relations
25-Oct-2005


Page: 1 2 3

Related medicine news :

1. Study, meta-analysis examine factors associated with death from heatstroke
2. Reanalysis of controversial meta-analysis says writing off rosiglitazone may be premature
3. Panel offers expert analysis on causes, prevention of stent thrombosis
4. Circumcision for prevention of HIV: new analysis demonstrates cost-effectiveness
5. Cost-benefit analysis: Combo treatment costs more, saves money later
6. Oral contraceptives increase risk for breast cancer in some women, meta-analysis finds
7. Beta-agonist inhalers more than double death rate in COPD patients, analysis shows
8. New analysis showed UC patients in clinical remission had higher rates of employment
9. Nanotechnology expert analysis: Huge impacts from tiny tech
10. WHI updated analysis: No increased risk of breast cancer with estrogen-alone
11. Awareness, analysis of tobacco advertising may go long way (baby) to prevent teen smoking

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: