HOME >> MEDICINE >> NEWS
New biodegradable magnesium stents for coronary arteries

Biodegradable magnesium stents have been developed to treat blockages in coronary arteries which can degrade within four months and achieve the same results as conventional stents, conclude authors of an Article published in this week's edition of The Lancet.

But both the Article and an accompanying Comment warn longer term follow-up of the patients fitted with biodegradable stents is needed.

Coronary stents improve immediate and late results of balloon angioplasty by closing up dissections and preventing collapse of the arterial walls.

Professor Raimund Erbel, Department of Cardiology, West German Heart Centre Essen, Germany, and colleagues successfully implanted 71 of the biodegradable magnesium stents in 63 patients in their study the PROGRESS-AMS clinical trial.

The researchers found that after 12 months, the stents were safe, with no incidence of stent thrombosis (clotting within the stent), heart attack or death in any of the patients. They found that the diameter of the blood vessel within the stent (in-stent acute gain) increased by an average of 1.41mm. Whilst the stent struts disappear over time, ultrasound confirms they remain present but have been absorbed into the vessel walls, with the space left behind "filled in."

The magnesium is eventually replaced by calcium and phosphorous through the body's natural processes.

However the trial also showed that angiographic restenosis (re-blocking of the artery) occurred in 47.5% of patients who received the biodegradable stents, and 27% needed target lesion vascularisation within 12 months due to recurrent ischaemia (lack of blood flow to the tissues).

The authors say: "This study showed that absorbable magnesium stents can be delivered and expanded at high pressure in artherosclerotic coronary arteries, providing good mechanical scaffolding and achieving a lumen enlargement similar to the immediate lumen gain obtained with conventional metall
'"/>

Contact: Professor Raimund Erbel
erbel@uk-essen.de
49-201-723-4800
Lancet
31-May-2007


Page: 1 2 3

Related medicine news :

1. New family of biodegradable polymers shows promise for intracellular drug delivery
2. Grain fiber and magnesium intake associated with lower risk for diabetes
3. Bare-metal stents are better for some heart patients
4. Off-label and untested use of drug-coated stents appears widespread
5. Studies highlight real world use, safety of drug-eluting stents
6. Jefferson scientists find that drug-eluting stents are disappointing in bypass grafts -- sometimes
7. SCAI issues clinical alert on drug-eluting stents and late thrombosis
8. SCAI president testifies before FDA on safety of drug-eluting stents
9. Dangers of stopping clopidogrel (Plavix) for patients with stents and certain other conditions
10. Studies compare stents and cardiac procedures for long-term survival
11. Drug-eluting and absorbable stents push interventional frontiers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... ... “The Journey: From the Mountains to the Mission Field”: the story of a missionary ... Journey: From the Mountains to the Mission Field” is the creation of published author, ... ages and currently teaches a class of ladies at her church, which she has ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and fastest ... to open a flagship location in Covington, LA at 401 N. U.S. Highway 190, ... next to Office Depot in the Holiday Square shopping center. Its location allows it ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a nationally recognized health ... expanded their existing home health joint venture through an agreement, effective October 1, ... joint venture home health company with Asante, delivering clinically integrated care, for the ...
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts at Children’s National ... 49th Congress of the International Society of Paediatric Oncology (SIOP) Oct. 12-15. ... for Cancer and Blood Disorders at Children’s National, and Stephen P. Hunger, M.D., ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... $3,296 in property taxes a year. In some states—like New York, New Jersey, ... By contrast, many overseas retirement havens have extremely low property-tax rates, which contributes ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... --  Provista, a proven leader in the supply ... power, today announced a new resource area on Provistaco.com ... is the online home for case studies, articles on ... releases, slideshows and events. ... at their fingertips, viewers can also watch short videos ...
(Date:10/2/2017)... , Oct. 2, 2017 Diplomat Pharmacy, Inc. ... Day Software and Consulting, LLC , and named its ... Software, based in Tennessee , will ... Day expands EnvoyHealth,s service offerings for health care partners ... "In an interoperable world, ...
(Date:9/28/2017)... CHICAGO , Sept. 28, 2017 Hill-Rom ... quarter 2017 earnings conference call and webcast on Friday, ... 8:00 a.m. (EDT) and ending at approximately 8:30 a.m. ... to discussing the company,s 2017 financial performance and guidance ... growth opportunities, initiatives to enhance operational performance, and long-range ...
Breaking Medicine Technology:
Cached News: