HOME >> MEDICINE >> NEWS
New bird flu drug promises to beat the problem of resistance

A new kind of drug to fight bird flu that will not suffer from the same kind of resistance problems as current treatments should begin clinical trials within the next three years, thanks to a new research grant.

Dr Andrew Watts from the University of Bath (UK) and Dr Jennifer McKimm-Breschkin from CSIRO (Australia) have been awarded over 408,000 from the Medical Research Council (MRC) to develop a new class of inhibitor they have discovered into a new kind of antiviral influenza drug.

The search for an alternative flu drug has become all the more pressing as the full extent of resistance the ability of the influenza virus to withstand drug treatments - becomes more widely understood.

Both Tamiflu and Relenza, the two drugs currently being stockpiled by governments in preparation for a global outbreak of bird flu, are inherently susceptible to resistance because of the way they work.

The first major warning of the practical implications of this came with research published in the New England Journal of Medicine in December 2005.

This reported that from a group of eight Vietnamese bird flu patients treated with Tamiflu (also known as Oseltamivir), two patients showed initial signs of recovery before eventually dying. This suggests that the influenza virus was able to rapidly develop resistance to the drug.

In another study in Japan, the virus developed resistance in one in six children treated with Tamiflu for ordinary forms of flu.

Although acting upon the same target on the influenza virus as existing treatments, the new drug molecules being developed are specific for a part of the virus that is unable to mutate (change), which means it should be impossible for the influenza virus to develop resistance.

"Tamiflu and Relenza remain our best lines of defence against a flu pandemic, but we need to be working on better alternatives that do not suffer the same inherent resistance proble
'"/>

Contact: Andrew McLaughlin
a.mclaughlin@bath.ac.uk
44-012-253-86883
University of Bath
7-Aug-2006


Page: 1 2 3

Related medicine news :

1. Fiber-based light source promises improvements in food inspection
2. Eastern philosophy promises hope for Western women with eating disorders
3. BC catalyst discovery promises faster, cheaper drug production
4. Solution to bacterial mystery promises new drugs
5. Purdue chemical-analysis method promises fast results
6. New rheumatoid arthritis drug developed at UCSD promises improved treatment options
7. Biotechnology has failed to live up to its promises
8. Promises made, promises kept?
9. Drug for cluster headaches may cause heart problems
10. Researchers find vitamin B1 deficiency key to vascular problems for diabetic patients
11. High blood pressure problems largely misunderstood by sufferers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... ... 2016 , ... A recent article published June 14 on E ... goes on to state that individuals are now more comfortable seeking to undergo not ... as calf and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians ...
(Date:6/24/2016)... ... , ... Marcy was in a crisis. Her son James, eight, was out of control. Prone ... physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If ... at my other children and say he was going to kill them. If we ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
(Date:6/24/2016)... ... , ... People across the U.S. are sharpening their pencils and honing their ... in which patients and their families pay tribute to a genetic counselor by nominating ... of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... The Grove Investment Group (TGIG), has initiated cultivation and processing operations at its ... Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete system ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 Research and Markets has ... Companion Diagnostic Tests" report to their offering. ... Diagnostics The World Market for Companion Diagnostics ... diagnostics. Market analysis in the report includes the following: ... Vitro Diagnostic Kits) by Region (N. America, EU, ROW), 2015-2020 ...
(Date:6/24/2016)... , Belgium , June ... MKT: VNRX), today announced the appointment of Dr. ... of Directors as a Non-Executive Director, effective June ... Company,s Audit, Compensation and Nominations and Governance Committees.  ... Dr. Futcher will provide independent expertise and strategic ...
(Date:6/23/2016)... Research and Markets has announced the addition of the ... report to their offering. ... failure, it replaces the function of kidneys by removing the ... the treatment helps to keep the patient body,s electrolytes such ... Increasing number of ESRD patients & substantial healthcare expenditure on ...
Breaking Medicine Technology:
Cached News: