HOME >> MEDICINE >> NEWS
New bird flu drug promises to beat the problem of resistance

A new kind of drug to fight bird flu that will not suffer from the same kind of resistance problems as current treatments should begin clinical trials within the next three years, thanks to a new research grant.

Dr Andrew Watts from the University of Bath (UK) and Dr Jennifer McKimm-Breschkin from CSIRO (Australia) have been awarded over 408,000 from the Medical Research Council (MRC) to develop a new class of inhibitor they have discovered into a new kind of antiviral influenza drug.

The search for an alternative flu drug has become all the more pressing as the full extent of resistance the ability of the influenza virus to withstand drug treatments - becomes more widely understood.

Both Tamiflu and Relenza, the two drugs currently being stockpiled by governments in preparation for a global outbreak of bird flu, are inherently susceptible to resistance because of the way they work.

The first major warning of the practical implications of this came with research published in the New England Journal of Medicine in December 2005.

This reported that from a group of eight Vietnamese bird flu patients treated with Tamiflu (also known as Oseltamivir), two patients showed initial signs of recovery before eventually dying. This suggests that the influenza virus was able to rapidly develop resistance to the drug.

In another study in Japan, the virus developed resistance in one in six children treated with Tamiflu for ordinary forms of flu.

Although acting upon the same target on the influenza virus as existing treatments, the new drug molecules being developed are specific for a part of the virus that is unable to mutate (change), which means it should be impossible for the influenza virus to develop resistance.

"Tamiflu and Relenza remain our best lines of defence against a flu pandemic, but we need to be working on better alternatives that do not suffer the same inherent resistance proble
'"/>

Contact: Andrew McLaughlin
a.mclaughlin@bath.ac.uk
44-012-253-86883
University of Bath
7-Aug-2006


Page: 1 2 3

Related medicine news :

1. Fiber-based light source promises improvements in food inspection
2. Eastern philosophy promises hope for Western women with eating disorders
3. BC catalyst discovery promises faster, cheaper drug production
4. Solution to bacterial mystery promises new drugs
5. Purdue chemical-analysis method promises fast results
6. New rheumatoid arthritis drug developed at UCSD promises improved treatment options
7. Biotechnology has failed to live up to its promises
8. Promises made, promises kept?
9. Drug for cluster headaches may cause heart problems
10. Researchers find vitamin B1 deficiency key to vascular problems for diabetic patients
11. High blood pressure problems largely misunderstood by sufferers

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/19/2017)... , ... August 18, 2017 , ... Western University of ... and education to launch the University’s new Center for Innovation on Wednesday, September 6, ... Education Center Lecture Hall 1, followed by a technology exhibition from 1 to 3 ...
(Date:8/19/2017)... ... , ... Curl Keeper® is excited to announce that the H2O Water Bottle ... for the second year in a row. The H2O Bottle, a refillable ultra-fine spray ... Moisturizer for Type 2 Wavies and Best Refresher for Type 2 Wavies in 2017. ...
(Date:8/19/2017)... Orlando, Fla. (PRWEB) , ... August 19, 2017 ... ... that Taufiq Ahmed, M.D., has joined its Orlando location as an interventional pain ... in anesthesiology, a focus on the treatment of migraine headaches, and significant experience ...
(Date:8/18/2017)... ... August ... ... For Immediate Release                Contact: Julian Teixeira, August 18, ... Sex and Relationship Advice from their Fathers , Contrary ...
(Date:8/18/2017)... ... August 18, 2017 , ... Mediaplanet today announces ... active, healthy lifestyles and highlighting the importance of proactive eye and ear health. ... shares the latest innovations in hearing aid technology. , In this issue, ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... 2017  AOTI Inc. announced today that its fully owned ... opened a New York City Office in Yonkers, New ... Topical Wound Oxygen (TWO 2 ) homecare therapy. This new East ... Health Care (ACHC) under the company,s DMEPOS accreditation for Home/Durable Medical ... Advanced Oxygen ...
(Date:8/10/2017)... -- Physical Rehabilitation Network (PRN), acquired the long-standing outpatient rehabilitation clinic, ... . The reputable clinic will continue to be co-owned and ... staff of four clinicians. Lipkin received his doctorate in physical ... years of experience with a strong background in manual therapy. ... 10th PRN clinic in and around the Denver ...
(Date:8/7/2017)... Aug. 7, 2017 Insightin Health, provider ... retention, and engagement, announced the selection of ... Product Development, effective as of February 2017. In this ... implementation strategy for our clients. Wood brings with ... consulting and business analytics within the healthcare industry. ...
Breaking Medicine Technology:
Cached News: