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New class of drug reduces post-operative vomiting

explore combining the NK-1 receptor antagonist with other anti-nausea medications to see if the overall rate of postoperative nausea and vomiting (PONV) can be reduced even more.

According to Gan, patients undergoing certain procedures tend to have higher rates of PONV. For example, more than 70 percent of patients undergoing brain surgery suffer from PONV. Since the act of vomiting can raise the pressure within brain, controlling this side effect is quite important for the medical recovery of these patients, Gan said. The same holds true for patients undergoing surgery of the upper gastrointestinal tract, he added, since the act of vomiting could cause sutures to come apart.


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Contact: Richard Merritt
Merri006@mc.duke.edu
919-684-4148
Duke University Medical Center
24-Oct-2005


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