HOME >> MEDICINE >> NEWS
New data show CAS in clinical practice has comparable MAE rate with pivotal sapphire trial

Cordis Endovascular, a division of Cordis Corporation, announced today that preliminary results of its CASES peri-approval study (CASES-PMS) showed that high surgical-risk patients treated with carotid artery stenting (CAS) had identical 30-day major adverse event (MAE) rates with that of patients treated with CAS in the pivotal SAPPHIRE study. The data, which were presented today at the American College of Cardiology Scientific Sessions, showed an MAE rate of 4.8 percent (62/1279) among patients treated with CAS in CASES-PMS compared with 4.8 percent (8/167) of CAS-treated patients in the randomized arm of the SAPPHIRE trial.

CASES-PMS is a multi-center, prospective, single arm open-label peri-approval study designed to assess the outcomes of stenting with Cordis' PRECISE* Nitinol Self-Expanding Stent, and ANGIOGUARD XP* Emboli Capture Guidewire System in the treatment of obstructive artery disease in relation to the outcomes of the pivotal SAPPHIRE study. The study's primary objective is to demonstrate that outcomes in a peri-approval setting, including use of a detailed training program in CAS for physicians not experienced in CAS, allow outcomes that are similar to those obtained in the pivotal trial setting.

"These initial findings are very important because they both corroborate the findings of the landmark SAPPHIRE study, and demonstrate that formalized training in carotid stenting allows physicians from multiple specialties with prior endovascular experience to perform carotid stenting and obtain outcomes as good as the experts that performed the clinical trials," said Dennis Donohoe, M.D., Vice President, Worldwide Regulatory and Clinical Affairs, Cordis Corporation. "The outcomes in this study are an important additional set of data supporting the generalizability of results from the SAPPHIRE trial, the only randomized clinical trial of carotid stenting compared to carotid endarterectomy."

Cordis Endovascular initiated CASES,
'"/>

Contact: Steven Cooper
steven.cooper@edelman.com
917-301-7566
Edelman Public Relations
13-Mar-2006


Page: 1 2

Related medicine news :

1. New contracts support clinical trials on antibiotic-resistant, community-acquired staph infections
2. Damon Runyon renews its $2.25 million investment to support young clinical cancer investigators
3. International journal group updates guidelines on registration of clinical trials
4. Urgent need for guidance on mobile phone use in clinical care
5. New prostate cancer clinical guidelines to be released
6. First clinical trial of gene therapy for childhood blindness
7. Acute coronary syndrome therapy improvements linked with fewer deaths and improved clinical outcomes
8. Taking the wraps off drug safety data from clinical trials
9. Preclinical results of Geovaxs AIDS vaccines demonstrate potential to protect against disease
10. 30+ AIDS vaccine clinical trials in 24 countries, research occurring on every continent
11. NIH-funded program co-directed by Mailman School of PH faculty to expedite clinical research process

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/1/2020)... , ... September 01, 2020 , ... ... with specialty fellowship training in aesthetic surgery of the face, breast, and body. ... the only female-owned premier boutique plastic surgery and aesthetic practice in Southwest Florida. ...
(Date:8/31/2020)... ... August 31, 2020 , ... Want to get moving, ... Palsy Alliance Research Foundation (CPARF) is thrilled to launch its fourth annual STEPtember campaign ... fully virtual challenge, STEPtember meets everyone wherever they are at this moment — encouraging ...
(Date:8/31/2020)... ... 31, 2020 , ... A Cure for Covid-19 “PTS” with Mediation & Hypnosis , At ... a state of panic, experiencing deep anxiety, immense stress, and right now are needing serious ... when most people on the planet are experiencing a great degree of emotional discomfort, be ...
(Date:8/28/2020)... JACKSONVILLE, Fla. (PRWEB) , ... August 28, 2020 ... ... that Forcura’s Founder & CEO Craig Mandeville was named an Entrepreneur Of The ... The Year program honors entrepreneurial business leaders whose ambitions deliver innovation, growth and ...
(Date:8/28/2020)... ... , ... Ziegler, a specialty investment bank, is pleased to ... a tech-enabled behavioral health and well-being solutions provider. , Synchronous Health, a ... (AI) to increase access and quality of behavioral health services, and Adventist Health, ...
Breaking Medicine News(10 mins):
(Date:9/2/2020)... ... September 02, 2020 , ... ... , Advanced Penetration Technology, LLC, (APT) a Texas- and Indiana-based company ( ... Over The Counter (OTC) products, was today provided results of an independent ...
(Date:9/1/2020)... ... 01, 2020 , ... Neil Oberfeld of global law firm ... Board of Trustees and committee chair of the Governance Committee for Mile High ... organization that fights for the education, health, and financial stability of residents across ...
(Date:8/31/2020)... ... August 31, 2020 , ... Welltech1, ... announced that they have invested $400,000 in PopBase, one of two start-ups that ... the Global Wellness Institute (GWI). , The competition was part of the ...
Breaking Medicine Technology:
Cached News: