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New drug could substantially reduce deaths from heart attack

ter hospital discharge could lead to further net gains, although the benefits and hazards of more long-term therapy are still under investigation."

In a second part of the study, also published in this week's issue, the group looked at the effect of giving patients early intravenous then oral metoprolol (beta-blocker therapy) in the emergency treatment of heart attacks. The team found that the treatment could cut the relative risk of repeat heart attack and of ventricular fibrillation** by about 15-20%, but increased the risk of cardiac shock by 30%, especially during the first day or so after admission. The authors' state that to maximise the benefits and minimise any potential hazard, it may generally be prudent to wait until a heart attack patient's condition has stabilised before starting beta-blocker therapy.


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Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
3-Nov-2005


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