HOME >> MEDICINE >> NEWS
New imaging compound might 'see' Alzheimer's earlier

A new imaging molecule that can detect and map plaques and tangles in the brains of people with Alzheimer's disease could eventually lead to earlier diagnosis of the devastating disease, researchers at the University of California, Los Angeles report in the Dec. 21, 2006, issue of the New England Journal of Medicine. The compound, developed by UCLA and called FDDNP, also holds promise as a research tool to evaluate new treatments for Alzheimer's. The study was funded in part by the National Institute on Aging (NIA), one of the National Institutes of Health (NIH).

FDDNP binds to plaques and tangles, enabling researchers to see these abnormal deposits that form in the brains of people with Alzheimer's disease on PET (positron emission tomography) scans. PET scans display maps of the brain that scientists use to understand brain function. In a clinical trial with volunteers who reported memory problems, results of PET scans using FDDNP correlated well with the volunteers' clinical diagnoses measured by performance on memory tests.

"Today, an estimated 4.5 million Americans have Alzheimer's disease, and that number could triple by 2050 as the population ages. We urgently need techniques to see brain changes in the earliest stages of cognitive decline so that we can identify people at risk and test drugs to stop or slow the progression of Alzheimer's," says NIA Director Richard J. Hodes, M.D.

In this study, Gary Small, M.D., of UCLA, led a research team that compared PET scans using FDDNP, PET scans using another molecule (FDG) to measure brain activity, and magnetic resonance imaging (MRI), which can show areas losing brain tissue in Alzheimer's disease. Of 83 people who volunteered for the trial, researchers classified 25 as having Alzheimer's, 28 as having mild cognitive impairment, and 30 as healthy. The FDDNP PET scans were more accurate than FDG PET scans or MRI at detecting differences among the groups of volunteers, the study found.
'"/>

Contact: Linda Joy
nianews3@mail.nih.gov
301-496-1752
NIH/National Institute on Aging
20-Dec-2006


Page: 1 2

Related medicine news :

1. UT study reveals inaccuracies in cardiac PET-CT imaging, finds fixes
2. Cars imaging reveals clues to myelin damage
3. Dartmouths alternative breast imaging techniques sort abnormal from normal tissue
4. UCLA imaging study reveals how pure oxygen harms the brain
5. SNMs 54th Annual Meeting speakers address state of molecular imaging/nuclear medicine technologies
6. Combined imaging approach may provide better identification of difficult-to-diagnose brain clots
7. Research agreement to advance new imaging technology
8. A closer look inside our lungs -- Penn researchers develop 2 novel imaging techniques
9. PET imaging identifies aggressive kidney cancers that require surgery
10. Picture this: FSU professors research could lead to vastly improved medical imaging
11. Using nanomagnets to enhance medical imaging

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/1/2020)... ... September 01, 2020 , ... ... practice in Glendale. While the office will be the first to bear ... tummy tucks, buttock augmentation (Brazilian butt lift), as well as rhinoplasty, facial rejuvenation, ...
(Date:9/1/2020)... ... 2020 , ... As fall and winter swiftly approach and many businesses cut ... taken this time to expand and grow into a full-fledged natural health clinic over ... will be relaunching its brand new website, expanding its services menu and has recruited ...
(Date:8/31/2020)... ... August 31, 2020 , ... The Lymphoma Research Foundation ... lymphoma research and serving the lymphoma community through a comprehensive series of education ... Blood Cancer Awareness Month (BCAM) and its international Light it Red for ...
(Date:8/31/2020)... ... August 31, 2020 , ... Want to get moving, break up your ... Foundation (CPARF) is thrilled to launch its fourth annual STEPtember campaign in the United ... STEPtember meets everyone wherever they are at this moment — encouraging people to move ...
(Date:8/31/2020)... ... August 31, 2020 , ... Smile Brands ... groups in the United States, today announced the grand opening of another affiliated ... , Patients will enjoy convenient hours, a comfortable office, and full-service care at ...
Breaking Medicine News(10 mins):
(Date:8/27/2020)... ... 27, 2020 , ... Trella Health, the leading source of ... cloud CRM, marketing automation, and contact center solutions for senior living communities and ... Trella’s performance intelligence data and insights into Enquire’s CRM solution to serve as ...
(Date:8/26/2020)... ... August 26, 2020 , ... ScripHessco has announced the ... infographic breaks down ways that chiropractors can help heal sports injuries and get ... “Athletes have an unusual amount of pressure and stress on their bodies, so ...
(Date:8/26/2020)... ... August 26, 2020 , ... Unscrupulous ... systems kill Coronavirus. While air purification technologies, including GreenTech Environmental’s proprietary methods, have ... Ebola, no air purification system has published results of singular and scientific testing ...
Breaking Medicine Technology:
Cached News: