HOME >> MEDICINE >> NEWS
New mechanism underlying pain found

thmic transmission."

Ion channels are openings that exist within a cell that allow the passage of certain ions into a cell to regulate activity. It is believed that hundreds of different types of ion channels exist in the body, each with a distinct responsibility for sending a specific message, and that specific pacemaker channels exist in peripheral nerves as well as in the heart and the central nervous system. In the heart, for instance, signals generated by pacemaker channels stimulate the heart muscle to contract, and in the brain, they control sleep and waking. Made up of glycoproteins, or proteins with sugar molecules attached, pacemaker channels -- also known as HCN channels (Hyperpolarization activated, Cyclic Nucleotide-gated cation channels) -- allow the entrance of sodium ions into the cell based on the configuration of the protein. Entry of sodium ions can trigger electrical activity in both cardiac cells and neurons.

"We think we have only scratched the surface in this area, as pacemaker channels may also play a role in inflammatory pain as well as other types, " said Dr. Wickenden. "More research is needed before this will translate to patient benefit, but the better understanding we've gained of the mechanism can enable us to narrow our focus."


'"/>

Contact: Ernie Knewitz
eknewitz@prdus.jnj.com
908-927-2953
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
15-Oct-2006


Page: 1 2

Related medicine news :

1. MU researchers find mechanisms that may unlock answers to Alzheimers disease
2. Study reveals aspirins colorectal cancer prevention mechanism
3. New mechanism identified for resistance to targeted lung cancer drugs
4. Important mechanism identified in the formation of blood vessels
5. Brain studies reveal the mechanisms of the voluntary control of visual attention
6. Researchers discover mechanism that determines when detailed memories are retained
7. Study identifies possible mechanism for brain damage in Huntingtons disease
8. Carnegie Mellon receives NIMH/NSF grant to examine mechanisms that underlie neuronal synchronization
9. Study uncovers mechanism of drug resistance in form of lung cancer
10. A novel mechanism of manganese-induced neurological dysfunction discovered
11. Drug triggers bodys mechanism to reverse aging effect on memory process

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New mechanism underlying pain found

(Date:5/26/2015)... 26, 2015 The American College of Traditional ... for the Open House/Free Application Day on Wednesday, July 22. ... 4 p.m. and will be held at ACTCM Pioneer Square, ... After checking in, attendees will be greeted with an introduction ... of the campus at 11:45 a.m. Lunch will be served ...
(Date:5/26/2015)... 2015 Irwin Gross, M.D., Accumen, ... hospital-wide Patient Blood Management (PBM) initiative at Eastern Maine ... usage by more than 60 percent and improved patient ... detail in an article in the May 2015 edition ... perioperative red cell loss, less acute kidney injury and ...
(Date:5/26/2015)... May 26, 2015 On May 26, 2015, ... 6 salesman and distributor Dwayne Windfall. At the start of ... company that has some unique characteristics with it, so could ... business?” Windfall replies saying, “I was reading the newspaper looking ... said they were looking for a person with hustle. I ...
(Date:5/26/2015)... Pasadena porcelain veneers dentist, Dr. ... cosmetic treatments. Cosmetic dentistry is becoming increasingly popular in ... are committed to providing you with the highest level ... and a smile of a lifetime … We work ... to change your life,” explains Dr. Martirosyan’s team. “Giving ...
(Date:5/26/2015)... Based on numerous suggestions put forward ... comprehensive upgrade of its purchasing page and processing, resulting ... users for their feedback and support of the website, ... transcription service promotion. , This promotion will become ... 9 this year. During this period, AnyTranscription users will ...
Breaking Medicine News(10 mins):Health News:ACTCM to Host Summer Open House 2Health News:Published Study: Patient Blood Management (PBM) Program Slashes Blood Use, Transfusions and Costs while Resulting in Better Patient Outcomes 2Health News:Published Study: Patient Blood Management (PBM) Program Slashes Blood Use, Transfusions and Costs while Resulting in Better Patient Outcomes 3Health News:My Positive Perspective Broadcasts Episode with Oceans 6 to Discuss Their Role in Helping the Community 2Health News:Pasadena Porcelain Veneers Expert, Marine Martirosyan DDS, is Now Offering Complimentary Dental Cleaning with Cosmetic Treatments 2Health News:Enjoy AnyTranscription’s First-class Audio/Video Transcription Service for Just $0.01 2Health News:Enjoy AnyTranscription’s First-class Audio/Video Transcription Service for Just $0.01 3
(Date:5/26/2015)... SALT LAKE CITY , May 26, ... healthcare data warehousing and analytics, today launched ... educational offering designed to help health systems ... their clinical quality and operational efficiency. ... latest offering in Health Catalyst,s comprehensive suite ...
(Date:5/26/2015)... May 26, 2015 ... announced the addition of the "North ... Type (Integrated Computerized Physician Order Entry, Standalone ... Software, Services) - Forecast to 2019 " ...      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , The ...
(Date:5/26/2015)... ® Technologies, Inc., the leader in non-invasive, accelerated orthodontic ... to continued demand from orthodontists and patients for safe, ... locations in the U.S. and Canada ... the only FDA-cleared Class II medical device that has ... much as 50 percent.  A recent ...
Breaking Medicine Technology:Introducing Health Catalyst Academy: An Innovative Approach for Accelerating Outcomes Improvement 2Introducing Health Catalyst Academy: An Innovative Approach for Accelerating Outcomes Improvement 3Introducing Health Catalyst Academy: An Innovative Approach for Accelerating Outcomes Improvement 4North American Computerized Physician Order Entry Market 2015-2019 2OrthoAccel Technologies Continues Trajectory of Accelerated Growth with Over 2,500 Practice Locations 2OrthoAccel Technologies Continues Trajectory of Accelerated Growth with Over 2,500 Practice Locations 3
Cached News: