HOME >> MEDICINE >> NEWS
New mechanism underlying pain found

thmic transmission."

Ion channels are openings that exist within a cell that allow the passage of certain ions into a cell to regulate activity. It is believed that hundreds of different types of ion channels exist in the body, each with a distinct responsibility for sending a specific message, and that specific pacemaker channels exist in peripheral nerves as well as in the heart and the central nervous system. In the heart, for instance, signals generated by pacemaker channels stimulate the heart muscle to contract, and in the brain, they control sleep and waking. Made up of glycoproteins, or proteins with sugar molecules attached, pacemaker channels -- also known as HCN channels (Hyperpolarization activated, Cyclic Nucleotide-gated cation channels) -- allow the entrance of sodium ions into the cell based on the configuration of the protein. Entry of sodium ions can trigger electrical activity in both cardiac cells and neurons.

"We think we have only scratched the surface in this area, as pacemaker channels may also play a role in inflammatory pain as well as other types, " said Dr. Wickenden. "More research is needed before this will translate to patient benefit, but the better understanding we've gained of the mechanism can enable us to narrow our focus."


'"/>

Contact: Ernie Knewitz
eknewitz@prdus.jnj.com
908-927-2953
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
15-Oct-2006


Page: 1 2

Related medicine news :

1. MU researchers find mechanisms that may unlock answers to Alzheimers disease
2. Study reveals aspirins colorectal cancer prevention mechanism
3. New mechanism identified for resistance to targeted lung cancer drugs
4. Important mechanism identified in the formation of blood vessels
5. Brain studies reveal the mechanisms of the voluntary control of visual attention
6. Researchers discover mechanism that determines when detailed memories are retained
7. Study identifies possible mechanism for brain damage in Huntingtons disease
8. Carnegie Mellon receives NIMH/NSF grant to examine mechanisms that underlie neuronal synchronization
9. Study uncovers mechanism of drug resistance in form of lung cancer
10. A novel mechanism of manganese-induced neurological dysfunction discovered
11. Drug triggers bodys mechanism to reverse aging effect on memory process

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/28/2017)... ... June 28, 2017 , ... ... servicing communities throughout the greater Cincinnati metropolitan area, is teaming up with the ... for families with children receiving treatment in nearby hospitals. , Ronald McDonald House ...
(Date:6/27/2017)... ... June 27, 2017 , ... Harbour , a DAO (decentralized ... the Ethereum blockchain, has released their technical specifications . , 2017 has seen ... little systematic approach for determining which offerings will garner the greatest ROI. Dean Eigenmann, ...
(Date:6/27/2017)... NY (PRWEB) , ... June 27, 2017 , ... From ... members. The three-day event was held in Syracuse, New York, where EarQ is headquartered. ... changing industry, how to connect with today’s savvy consumer, and the latest in ...
(Date:6/27/2017)... ... June 27, 2017 , ... PR News is looking for ... guidebook. This guidebook offers an excellent branding and exposure opportunity for the author ... and how-to’s that fall into the following categories:, ,     Media ...
(Date:6/27/2017)... ... June 27, 2017 , ... Hammer Strength, the world’s leading performance ... Javair Gillett of the Houston Rockets the NBSCA Strength & Conditioning Coach of the ... by NBSCA members who vote to select the coach who embodies the highest level ...
Breaking Medicine News(10 mins):
(Date:5/29/2017)... Israel, May 29, 2017  Cellect Biotechnology Ltd. (NASDAQ: ... technology which enables the functional selection of stem cells, ... for the first quarter ended March 31 st , ... our accomplishments in the first quarter of 2017," said ... quarter, we announced the treatment of the first blood ...
(Date:5/24/2017)... , May 24, 2017  ivWatch LLC ... Equipment Manufacturer (OEM) Board to enable seamless integration ... patient monitoring systems, infusion pumps and other devices. ... will be able to help health care customers ... reduced risks related to IV therapy. ...
(Date:5/22/2017)... 22, 2017  As the specialty pharmacy industry ... to make the revolutionary shift from volume-based to ... ensuring positive patient outcomes and shaping the future ... focus away from clinical trials and toward data ... specialty drug therapy utilization in precise patient populations. ...
Breaking Medicine Technology:
Cached News: