HOME >> MEDICINE >> NEWS
New mechanism underlying pain found

thmic transmission."

Ion channels are openings that exist within a cell that allow the passage of certain ions into a cell to regulate activity. It is believed that hundreds of different types of ion channels exist in the body, each with a distinct responsibility for sending a specific message, and that specific pacemaker channels exist in peripheral nerves as well as in the heart and the central nervous system. In the heart, for instance, signals generated by pacemaker channels stimulate the heart muscle to contract, and in the brain, they control sleep and waking. Made up of glycoproteins, or proteins with sugar molecules attached, pacemaker channels -- also known as HCN channels (Hyperpolarization activated, Cyclic Nucleotide-gated cation channels) -- allow the entrance of sodium ions into the cell based on the configuration of the protein. Entry of sodium ions can trigger electrical activity in both cardiac cells and neurons.

"We think we have only scratched the surface in this area, as pacemaker channels may also play a role in inflammatory pain as well as other types, " said Dr. Wickenden. "More research is needed before this will translate to patient benefit, but the better understanding we've gained of the mechanism can enable us to narrow our focus."


'"/>

Contact: Ernie Knewitz
eknewitz@prdus.jnj.com
908-927-2953
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
15-Oct-2006


Page: 1 2

Related medicine news :

1. MU researchers find mechanisms that may unlock answers to Alzheimers disease
2. Study reveals aspirins colorectal cancer prevention mechanism
3. New mechanism identified for resistance to targeted lung cancer drugs
4. Important mechanism identified in the formation of blood vessels
5. Brain studies reveal the mechanisms of the voluntary control of visual attention
6. Researchers discover mechanism that determines when detailed memories are retained
7. Study identifies possible mechanism for brain damage in Huntingtons disease
8. Carnegie Mellon receives NIMH/NSF grant to examine mechanisms that underlie neuronal synchronization
9. Study uncovers mechanism of drug resistance in form of lung cancer
10. A novel mechanism of manganese-induced neurological dysfunction discovered
11. Drug triggers bodys mechanism to reverse aging effect on memory process

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New mechanism underlying pain found

(Date:2/28/2015)... In a recent episode of SCI ... Change Athlete Development Services and Consultancy talks with ... athlete development and player engagement during and after their ... athletes face and how off-field activities are a critical ... involved in athlete development issues while in graduate school ...
(Date:2/28/2015)... The Classic Denture Center , located in ... Throughout all of March patients can receive $25 off ... can help overall mouth health and give patients ... certain symptoms that suggest the denture teeth are in ... 1.    Pain, clicking, and popping in the joints, 2.    Pain behind ...
(Date:2/28/2015)... February 28, 2015 Indosoft Inc ... suite for Asterisk, are pleased to announce the development ... 5.7 and 5.8 versions of Q-Suite, this new version ... a number of new features to the leading edge ... , Q-Suite 5.9 will add features to enhance security ...
(Date:2/28/2015)... Pioneer Millworks reclaimed USA wood will be on ... Show, an annual, premier sustainable building event in Tokyo, ... manufacturers of the latest building products, services and technology. ... manufactured by Pioneer Millworks from their Oregon and New ... hotels, retailers, and corporate offices. Nichibi Global , ...
(Date:2/28/2015)... York, NY (PRWEB) February 28, 2015 ... discuss federal testosterone lawsuits that have been filed by ... for the second week in March, the Firm notes. ... Court’s website, parties involved in the federal litigation will ... address matters related to prescription therapy treatments designed to ...
Breaking Medicine News(10 mins):Health News:SCI TV Covers Athlete Development with Duncan Fletcher 2Health News:SCI TV Covers Athlete Development with Duncan Fletcher 3Health News:Classic Denture Center in Portland Oregon is Offering March Discount 2Health News:Indosoft Proudly Announces Q-Suite 5.9 Call Center Software for Asterisk 2Health News:US Reclaimed Wood from Pioneer Millworks to be Featured at Architecture & Construction Materials Show in Tokyo. 2Health News:Bernstein Liebhard LLP Notes Approaching Conference in Federal Litigation that Includes Numerous Testosterone Lawsuits Filed by the Firm 2Health News:Bernstein Liebhard LLP Notes Approaching Conference in Federal Litigation that Includes Numerous Testosterone Lawsuits Filed by the Firm 3Health News:Bernstein Liebhard LLP Notes Approaching Conference in Federal Litigation that Includes Numerous Testosterone Lawsuits Filed by the Firm 4
(Date:2/27/2015)... NEWTON, Mass. and JERUSALEM ... privately-held biopharma company developing octreotide capsules, its lead product ... of a $70 million Series E financing round. Participants ... and Sofinnova Ventures, and an undisclosed blue chip public ... F2 Capital, 7 Med Health Ventures, Abingworth and ARCH ...
(Date:2/26/2015)... -- Tandem Diabetes Care®, Inc. (NASDAQ: TNDM ), ... and t:flex™ Insulin Pumps, today announced the pricing of ... common stock at a price to the public of ... this offering are expected to be $56.3 million, after ... expenses payable by Tandem. All of the shares of ...
(Date:2/26/2015)...  Mobility Ventures LLC, an AM General Company, is ... (NYSE: BAC ) that will make it ... revolutionary MV-1 - - the world,s first and only ... provide safe and comfortable transportation for all passengers including ... purchase a new MV-1 vehicle at the over 150 ...
Breaking Medicine Technology:Chiasma Announces Completion of $70 Million Series E Financing 2Chiasma Announces Completion of $70 Million Series E Financing 3Tandem Diabetes Care Announces Pricing of Underwritten Public Offering of Common Stock 2Tandem Diabetes Care Announces Pricing of Underwritten Public Offering of Common Stock 3Mobility Ventures and Bank of America Announce New Agreement to Simplify Retail Consumer Financing for MV-1 Universally Accessible Vehicle 2Mobility Ventures and Bank of America Announce New Agreement to Simplify Retail Consumer Financing for MV-1 Universally Accessible Vehicle 3
Cached News: