HOME >> MEDICINE >> NEWS
New medication appears effective in helping smokers kick the habit

A drug recently approved by the U.S. Food and Drug Administration as an aid to smoking cessation appears effective both short- and long-term for smokers trying to quit, according to two reports in the August 14/28 issue of the Archives of Internal Medicine, one of the JAMA/Archives journals.

Smoking is the leading cause of preventable death in the United States and worldwide. Currently available pharmacotherapies for smoking cessation include nicotine replacement therapy (NRT)--such as gum, skin patches, tablets, nasal spray and inhalers--and the antidepressant drugs bupropion hydrochloride and nortriptyline hydrochloride. These have shown limited success rates, with success at one year averaging approximately seven percent to 30 percent, according to background information in the articles.

The new drug varenicline tartrate mimics the effects of nicotine to help offset cravings, and in the presence of nicotine it helps suppress some of the reinforcing effects of smoking.

Mitchell Nides, Ph.D., of Los Angeles Clinical Trials, and colleagues with the Varenicline Study Group conducted a randomized, double-blind, placebo-controlled study to evaluate the efficacy, tolerability and safety of varenicline for smoking cessation. Healthy smokers aged 18 to 65 years were randomly assigned to receive varenicline in a dosage of .3 milligrams once daily, 1 milligram once daily, or 1 milligram twice daily for six weeks, plus placebo for one week; to 150 milligrams of sustained-release bupropion hydrochloride twice daily for seven weeks; or to placebo for seven weeks.

The authors report that varenicline, in combination with brief behavioral counseling, was more effective for short- and long-term smoking cessation than placebo.

"Efficacy improved as the dose increased, with varenicline tartrate, 1 milligram twice daily, providing the highest rates of continuous abstinence across all treatment groups, including bupropio
'"/>

Contact: Media Relations
mediarelations@jama-archives.org
312-464-5262
JAMA and Archives Journals
14-Aug-2006


Page: 1 2 3 4 5

Related medicine news :

1. Adding medication improves recovery for elderly with depression, says Pitt School of Medicine study
2. Heart failure medication does not improve survival, compared to more widely used medication
3. Commonly used pain medications do not prevent Alzheimers disease
4. Standard long-acting insulin as good as newer medications
5. MS patients not receiving medications to slow disease progression, research shows
6. Study sheds light on medication treatment options for bipolar disorder
7. Landmark schizophrenia treatment study reveals that medication alone is not always effective
8. Cost control measures limit patient and physician choice in psychotropic medications
9. Residents in disaster areas face medication adherence dilemmas
10. Improved adherence to certain medications associated with longer survival following heart attack
11. Many children discontinuing use of ADHD medication

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/15/2018)... Tenn. (PRWEB) , ... November 15, 2018 , ... ... Dehner has been designated as a UroLift® Center of Excellence. The designation recognizes ... the UroLift System and demonstrated a commitment to exemplary care for men suffering ...
(Date:11/14/2018)... (PRWEB) , ... November 14, 2018 , ... ... Jordan Pisarcik, Vice President, Account Management at DocASAP, will host a session titled ... WHAT:, Hosted by American Medical Group Association (AMGA), the 2018 Institute for Quality ...
(Date:11/14/2018)... ... November 14, 2018 , ... “The ... Nov. 1, 2018 and continues through Dec. 15, 2018). Enrolling in the Marketplace ... does not have to be an overwhelming process,” explained Bob Dial, Chief Compliance ...
(Date:11/13/2018)... ... , ... A survey by the publishers of ADC Review | Journal ... reached U.S. $ 4 billion. Approximately forty-five percent of this market included Antibody-drug Conjugates ... ADCs) is expected to grow significantly, to U.S. $ 17 billion by 2023. [1][2][3] ...
(Date:11/13/2018)... ... 13, 2018 , ... Dahryn Trivedi is on a mission ... the arena of science. , Dahryn has impacted thousands of individuals around the ... relief, inner peace, mental clarity, enhanced intuition, greater happiness and a deep feeling ...
Breaking Medicine News(10 mins):
(Date:11/14/2018)... ... November 14, 2018 , ... ... proud to announce a new partnership with DNASTAR, a software company that has ... supports molecular biology, structural biology and genomics. Bioz is a life science literature-exploration ...
(Date:11/14/2018)... , ... November 14, 2018 ... ... Aspirus Medevac is being awarded accreditation for their ground ambulance ... Medical Transport Applications (NAAMTA). , NAAMTA Accreditation is founded upon ...
(Date:11/13/2018)... ... November 13, 2018 , ... ... (almost 5,000 per day), yet its underlying technology has not seen significant change ... an Ohio-based company that is making surgery smarter by developing tools for a ...
Breaking Medicine Technology:
Cached News: