HOME >> MEDICINE >> NEWS
New medication appears effective in helping smokers kick the habit

A drug recently approved by the U.S. Food and Drug Administration as an aid to smoking cessation appears effective both short- and long-term for smokers trying to quit, according to two reports in the August 14/28 issue of the Archives of Internal Medicine, one of the JAMA/Archives journals.

Smoking is the leading cause of preventable death in the United States and worldwide. Currently available pharmacotherapies for smoking cessation include nicotine replacement therapy (NRT)--such as gum, skin patches, tablets, nasal spray and inhalers--and the antidepressant drugs bupropion hydrochloride and nortriptyline hydrochloride. These have shown limited success rates, with success at one year averaging approximately seven percent to 30 percent, according to background information in the articles.

The new drug varenicline tartrate mimics the effects of nicotine to help offset cravings, and in the presence of nicotine it helps suppress some of the reinforcing effects of smoking.

Mitchell Nides, Ph.D., of Los Angeles Clinical Trials, and colleagues with the Varenicline Study Group conducted a randomized, double-blind, placebo-controlled study to evaluate the efficacy, tolerability and safety of varenicline for smoking cessation. Healthy smokers aged 18 to 65 years were randomly assigned to receive varenicline in a dosage of .3 milligrams once daily, 1 milligram once daily, or 1 milligram twice daily for six weeks, plus placebo for one week; to 150 milligrams of sustained-release bupropion hydrochloride twice daily for seven weeks; or to placebo for seven weeks.

The authors report that varenicline, in combination with brief behavioral counseling, was more effective for short- and long-term smoking cessation than placebo.

"Efficacy improved as the dose increased, with varenicline tartrate, 1 milligram twice daily, providing the highest rates of continuous abstinence across all treatment groups, including bupropio
'"/>

Contact: Media Relations
mediarelations@jama-archives.org
312-464-5262
JAMA and Archives Journals
14-Aug-2006


Page: 1 2 3 4 5

Related medicine news :

1. Adding medication improves recovery for elderly with depression, says Pitt School of Medicine study
2. Heart failure medication does not improve survival, compared to more widely used medication
3. Commonly used pain medications do not prevent Alzheimers disease
4. Standard long-acting insulin as good as newer medications
5. MS patients not receiving medications to slow disease progression, research shows
6. Study sheds light on medication treatment options for bipolar disorder
7. Landmark schizophrenia treatment study reveals that medication alone is not always effective
8. Cost control measures limit patient and physician choice in psychotropic medications
9. Residents in disaster areas face medication adherence dilemmas
10. Improved adherence to certain medications associated with longer survival following heart attack
11. Many children discontinuing use of ADHD medication

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/19/2019)... ... 19, 2019 , ... Crabapple Dental is a full-service ... state-of-the-art dental treatments in a comfortable environment. Dr. Sarah Roberts leads the Milton ... for providing advanced services in cosmetic and restorative dentistry, including minimally invasive dental ...
(Date:2/19/2019)... YORK (PRWEB) , ... February 19, 2019 , ... ... Dave,” a cancer survivor and well-respected advocate for patient engagement, will deliver the ... Business Conference. deBronkart brings critical awareness of participatory medicine and empowering partnerships between ...
(Date:2/19/2019)... ... February 19, 2019 , ... According to a recent study by Columbia University, ... and daily routines; and only 26% of widows return to their pre-loss level of ... spouse is one of the most tragic events that one can face. Consequently, many ...
(Date:2/19/2019)... ... 18, 2019 , ... AdventHealth Connerton is the first specialty ... Stations to maximize infection control for patients and their families. The patented, new ... C. difficile, which can be transmitted from the bottoms of shoes to patients, ...
(Date:2/19/2019)... ... February 19, 2019 , ... Dr. Dana Schroeder’s new ... Have the Life You Want!” (published by Balboa Press), shares practical advice, personal ... release the pounds, reconnect to their dreams and attain fulfillment. , Schroeder helps ...
Breaking Medicine News(10 mins):
(Date:2/19/2019)... ... February 19, 2019 , ... ... completed his new book “Live Hard Die Young.” Dr. Oexner was the first ... medicine, therapeutic exercise physiology, and nutritional counseling. Dr. Oexner was a supervisor on ...
(Date:2/16/2019)... ... February 15, 2019 , ... In ... of Perio-Implant Care are urging patients to take their oral health seriously. With ... Alzheimer's and dementia, and risk of pre-term birth, there is plenty to be ...
(Date:2/16/2019)... ... February 15, 2019 , ... Dr. Lucas ... Beauty network. , The Haute Beauty Network, well known for their exclusivity, and ... Face expert and our newest addition to the Haute Living partnership. , Haute ...
Breaking Medicine Technology:
Cached News: