HOME >> MEDICINE >> NEWS
New project to analyze why Polycystic Ovary Syndrome and insulin resistance are so closely linked

Understanding the link between Polycystic Ovary Syndrome (PCOS) and insulin resistance is the aim of a new project announced today, funded by the charity WellBeing of Women.

It is known that women with PCOS have a 3-fold increase in their risk of developing type-2 diabetes, where the body does not produce enough insulin or cannot use insulin properly. Insulin resistance is an important factor in the condition, which is the most common female hormone disorder. PCOS affects between 5 and 10 per cent of women and is a major cause of infertility.

The new 97K project aims to identify a defective point on the insulin signalling pathway in women with PCOS. The researchers, from Imperial College London, hope this will enable the development of new therapies which target this part of the pathway, to counter the insulin resistance and the fertility problems that PCOS can cause.

Insulin is released from cells in the pancreas after eating and it signals insulin-sensitive tissues (such as fat and muscle) to take up glucose, keeping glucose levels in the bloodstream normal. In people with insulin resistance, normal amounts of insulin are not adequate to produce a normal glucose response, meaning that levels of insulin in the bloodstream need to be higher to achieve normal blood sugar levels.

Insulin resistance (and/or the compensatory excess of insulin in the bloodstream), may contribute to abnormalities in function of the ovaries that lead to many of the symptoms of PCOS. These include irregular periods, or no periods at all; fertility problems; weight gain; acne; and excessive hair growth (hirsutism).

A longer term concern is that insulin resistance also predisposes people to diabetes. In some patients the pancreas is unable, in the long-term, to produce enough insulin to compensate for the resistance of the tissues to insulin action. Consequently, blood sugar levels rise. What is not known is why PCOS and insulin resista
'"/>

Contact: Laura Gallagher
L.Gallagher@imperial.ac.uk
44-020-759-46702
Imperial College London
12-Mar-2007


Page: 1 2

Related medicine news :

1. Test project of patient-centered medical home model endorsed by American College of Physicians
2. Spanish project AmIVital creates intelligent communication devices for elderly and disabled people
3. Healthy schools project gets an A
4. Liverpool launches 20 million project to develop medicines for children
5. New family health history projects focus on Alaska Native, Appalachian communities
6. ESSP launches project on the effects of global environmental change on human health
7. Global Environmental Change and Human Health: New project launched at GEC Conference in Beijing
8. Clean water project hit by funding drought
9. $500,000 grant launches health literacy project to benefit older adults
10. St. Jude projects 90 percent cure rate for ALL
11. Virtual microscopy project wins educational technology award

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/16/2017)... ... August 16, 2017 , ... Maury Regional Health has announced a large-scale ... broadly deploying AccuVein devices, Maury Regional Medical Center is making vein visualization part of ... a needle stick and more importantly, helps our staff members locate a vein that ...
(Date:8/16/2017)... ... August 16, 2017 , ... With a new PD diagnosis every nine minutes, ... , The grants are awarded through a competitive application process and reviewed by APDA’s ... backgrounds and expertise in all areas relevant to PD research. The SAB meets ...
(Date:8/16/2017)... , ... August 16, 2017 , ... ... $5.99, eBook, 9781498499620    ) shares that during the time of a cancer diagnosis, surgery ... of God's love, and all the many ways God shows love to those ...
(Date:8/16/2017)... Lake Orion, Rochester, Michigan (PRWEB) , ... August ... ... now offer treatment options to patients suffering from chronic pelvic pain. In ... treatment of various pelvic pain disorders including endometriosis, menorrhagia (abnormal heavy bleeding during ...
(Date:8/16/2017)... ... August 16, 2017 , ... With low back pain afflicting 8 of 10 Americans at ... kissing cousin – upper back pain. But this equally vexing condition stems from a variety ... Kaixuan Liu, MD, PhD , founder and president of Atlantic Spine Center. , ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... Diplomat Pharmacy, Inc. (NYSE: DPLO), is now ... residents. Naloxone is available without a ... pharmacy, G-3320 Beecher Road. ... Administration, is intended to block or reverse the effects ... of consciousness. The medication is often carried by first ...
(Date:8/11/2017)... Israel , Aug. 11, 2017 DarioHealth ... with mobile health and big data solutions, today announced ... on Monday, August 14 and host a conference call ... quarter 2017 operating and financial results and its strategy ... will be hosted by Erez Raphael , Chief ...
(Date:8/7/2017)... WARSAW, Ind. , Aug. 7, 2017 Zimmer ... in musculoskeletal healthcare, today announced that its Board of Directors ... stockholders for the third quarter of 2017. ... will be paid on or about October 27, 2017 to ... September 22, 2017.  Future declarations of dividends are subject to ...
Breaking Medicine Technology:
Cached News: