HOME >> MEDICINE >> NEWS
New project to analyze why Polycystic Ovary Syndrome and insulin resistance are so closely linked

Understanding the link between Polycystic Ovary Syndrome (PCOS) and insulin resistance is the aim of a new project announced today, funded by the charity WellBeing of Women.

It is known that women with PCOS have a 3-fold increase in their risk of developing type-2 diabetes, where the body does not produce enough insulin or cannot use insulin properly. Insulin resistance is an important factor in the condition, which is the most common female hormone disorder. PCOS affects between 5 and 10 per cent of women and is a major cause of infertility.

The new 97K project aims to identify a defective point on the insulin signalling pathway in women with PCOS. The researchers, from Imperial College London, hope this will enable the development of new therapies which target this part of the pathway, to counter the insulin resistance and the fertility problems that PCOS can cause.

Insulin is released from cells in the pancreas after eating and it signals insulin-sensitive tissues (such as fat and muscle) to take up glucose, keeping glucose levels in the bloodstream normal. In people with insulin resistance, normal amounts of insulin are not adequate to produce a normal glucose response, meaning that levels of insulin in the bloodstream need to be higher to achieve normal blood sugar levels.

Insulin resistance (and/or the compensatory excess of insulin in the bloodstream), may contribute to abnormalities in function of the ovaries that lead to many of the symptoms of PCOS. These include irregular periods, or no periods at all; fertility problems; weight gain; acne; and excessive hair growth (hirsutism).

A longer term concern is that insulin resistance also predisposes people to diabetes. In some patients the pancreas is unable, in the long-term, to produce enough insulin to compensate for the resistance of the tissues to insulin action. Consequently, blood sugar levels rise. What is not known is why PCOS and insulin resista
'"/>

Contact: Laura Gallagher
L.Gallagher@imperial.ac.uk
44-020-759-46702
Imperial College London
12-Mar-2007


Page: 1 2

Related medicine news :

1. Test project of patient-centered medical home model endorsed by American College of Physicians
2. Spanish project AmIVital creates intelligent communication devices for elderly and disabled people
3. Healthy schools project gets an A
4. Liverpool launches 20 million project to develop medicines for children
5. New family health history projects focus on Alaska Native, Appalachian communities
6. ESSP launches project on the effects of global environmental change on human health
7. Global Environmental Change and Human Health: New project launched at GEC Conference in Beijing
8. Clean water project hit by funding drought
9. $500,000 grant launches health literacy project to benefit older adults
10. St. Jude projects 90 percent cure rate for ALL
11. Virtual microscopy project wins educational technology award

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/26/2017)... ... February 26, 2017 , ... This is an ... world’s first to be ISO/IEC 17025:2005 INAB accredited for Der p 1 (house ... is the globally recognised standard that sets out requirements for the technical competence ...
(Date:2/26/2017)... ... February 26, 2017 , ... ... distribution in North America, today announced it would be offering some it’s exclusive ... prides itself on crafting quality and unique baby clothing/feeding products, will team up ...
(Date:2/26/2017)... ... February 26, 2017 , ... ... new technology standard in staffing, scheduling, and reporting for healthcare organizations. This ... activity throughout the entire staffing process. StaffBridge technology improves staffing efficiency, maximizes ...
(Date:2/26/2017)... Florida (PRWEB) , ... February 26, 2017 , ... ... (PD) patients after receiving cognitive rehabilitation, according to a study released today at ... known that cognitive rehabilitation programs are proven to be effective in improving cognitive ...
(Date:2/25/2017)... ... , ... FCPX users now have the ability to sharpen a desired color ... users have total control over sharpening amount, sharpening radius, threshold, horizontal sharpening, vertical sharpening, ... users can visually see the color range effected with ease all within Final ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)...  Today, exocad America and the Biodenta Group ... path to produce 510(K) cleared, in-house milled, custom ... into exocad DentalCAD software. In order to achieve ... Processes (GMP,s) into their organization, sign up as ... audit process. Then, dental labs can use Biodenta,s milling ...
(Date:2/24/2017)... -- Research and Markets has announced the addition of the ... their offering. ... research Hemophilia Drugs Price Analysis and Strategies - 2016, provides drug pricing ... the following questions: What are the key ... in the Global Hemophilia market? What are the unit ...
(Date:2/24/2017)... , Feb. 24, 2017 Juan ... & Associates PC , a boutique securities firm headquartered ... York City , announces that a class action ... Massachusetts  against Inotek Pharmaceuticals Corporation (NASDAQ: ... the Company,s securities between July 23, 2015 and December 30, ...
Breaking Medicine Technology:
Cached News: