HOME >> MEDICINE >> NEWS
New project to analyze why Polycystic Ovary Syndrome and insulin resistance are so closely linked

Understanding the link between Polycystic Ovary Syndrome (PCOS) and insulin resistance is the aim of a new project announced today, funded by the charity WellBeing of Women.

It is known that women with PCOS have a 3-fold increase in their risk of developing type-2 diabetes, where the body does not produce enough insulin or cannot use insulin properly. Insulin resistance is an important factor in the condition, which is the most common female hormone disorder. PCOS affects between 5 and 10 per cent of women and is a major cause of infertility.

The new 97K project aims to identify a defective point on the insulin signalling pathway in women with PCOS. The researchers, from Imperial College London, hope this will enable the development of new therapies which target this part of the pathway, to counter the insulin resistance and the fertility problems that PCOS can cause.

Insulin is released from cells in the pancreas after eating and it signals insulin-sensitive tissues (such as fat and muscle) to take up glucose, keeping glucose levels in the bloodstream normal. In people with insulin resistance, normal amounts of insulin are not adequate to produce a normal glucose response, meaning that levels of insulin in the bloodstream need to be higher to achieve normal blood sugar levels.

Insulin resistance (and/or the compensatory excess of insulin in the bloodstream), may contribute to abnormalities in function of the ovaries that lead to many of the symptoms of PCOS. These include irregular periods, or no periods at all; fertility problems; weight gain; acne; and excessive hair growth (hirsutism).

A longer term concern is that insulin resistance also predisposes people to diabetes. In some patients the pancreas is unable, in the long-term, to produce enough insulin to compensate for the resistance of the tissues to insulin action. Consequently, blood sugar levels rise. What is not known is why PCOS and insulin resista
'"/>

Contact: Laura Gallagher
L.Gallagher@imperial.ac.uk
44-020-759-46702
Imperial College London
12-Mar-2007


Page: 1 2

Related medicine news :

1. Test project of patient-centered medical home model endorsed by American College of Physicians
2. Spanish project AmIVital creates intelligent communication devices for elderly and disabled people
3. Healthy schools project gets an A
4. Liverpool launches 20 million project to develop medicines for children
5. New family health history projects focus on Alaska Native, Appalachian communities
6. ESSP launches project on the effects of global environmental change on human health
7. Global Environmental Change and Human Health: New project launched at GEC Conference in Beijing
8. Clean water project hit by funding drought
9. $500,000 grant launches health literacy project to benefit older adults
10. St. Jude projects 90 percent cure rate for ALL
11. Virtual microscopy project wins educational technology award

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/25/2016)... ... 2016 , ... CloudLIMS, joins an elite number of companies that have earned ... of 2016 by CIOReview. , In a deliberate session with the honorary industrial experts, ... has been concluded with. The positioning is based on evaluation of CloudLIMS’ specialties in ...
(Date:5/25/2016)... ... ... The Global Wellness Summit (GWS) today announced that its 2016 agenda will ... continent that pioneered the medical/wellness concept for the world. , Delegates to the 10th ... Henri Chenot, Founder of the Chenot Group, which operates wellness centers around the world ...
(Date:5/25/2016)... ... ... The University of San Francisco (USF) has named Margaret Wooding Baker dean ... more than 100 full-time faculty and staff, and serve as a member of the ... Baker comes to USF from the University of Washington in Seattle, where she is ...
(Date:5/25/2016)... , ... May 25, 2016 , ... ... insurance, has seen a significant spike in their clients' employee participation for their ... biometric health screening by implementing a high-deductible health plan with outcome-based deductible incentives. ...
(Date:5/25/2016)... ... May 25, 2016 , ... Stern Environmental Group ... be selling the device branded as Stern’s Real Time Monitoring (RTM) Device. ... to the hotel and motel industry, colleges for use in dormitories, shelters, and nursing ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... CHESTERFIELD, Va. , May 25, 2016 /PRNewswire/ ... next-generation sequencing test for wounds and infections. This ... ALL parasites, and select viruses. The test requires ... area. David G. Bostwick ... molecular testing to facilitate wound healing: "We are ...
(Date:5/24/2016)... AMSTERDAM , May 24, 2016 ... auf den Markt gebracht, die es Ärzten erlaubt, ... überall zu behandeln: MDLinking kombiniert Live Streaming mit ... sicheren Umfeld zu kommunizieren. Mediziner in Europa, Afrika, ... haben sich bereits für die Plattform registriert. ...
(Date:5/24/2016)... New Zealand , May 24, 2016 ... and informatics solutions for the healthcare sector, has been named ... New Zealand Hi-Tech Awards 2016. Dr Bruce ... fantastic acknowledgement for our team.  It,s really good to be ... burden healthcare internationally. Our products are used in 35 countries ...
Breaking Medicine Technology:
Cached News: