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New project to analyze why Polycystic Ovary Syndrome and insulin resistance are so closely linked

nce are so closely related.

The researchers hope that the new project will explain the link between PCOS and insulin resistance and how the link manifests itself at the level of individual cells.

The researchers will be looking at how ovarian cells metabolise glucose in women both with and without PCOS.

Professor Stephen Franks said: "PCOS gives rise to a range of symptoms. These may be very distressing not only because of problems with irregular periods and with fertility but also because of excess body hair, acne or alopecia. We still do not fully understand the underlying cause or causes of PCOS but insulin resistance plays an important part in many patients.

"These studies will give us the chance to look directly at the mechanism of insulin resistance at the level of an important target tissue the ovary. We expect the results of these studies to give us information that will help to devise new and more effective methods of treatment for this very common hormone problem," he added.


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Contact: Laura Gallagher
L.Gallagher@imperial.ac.uk
44-020-759-46702
Imperial College London
12-Mar-2007


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