HOME >> MEDICINE >> NEWS
New research links metabolism and appetite suppression, opening door to obesity treatments

Ottawa A team led by a Canadian researcher has discovered a process by which a small protein acts directly within muscles to increase the body's metabolism to burn fat while simultaneously suppressing appetite. These findings suggest that the protein, known as the ciliary neurotrophic factor (CNTF), could play a key role as a weight loss agent.

Until recently, most obesity research has focused on the regulation of appetite by hormones such as leptin. Research led by Dr. Greg Steinberg ─ a Target Obesity fellow funded by the Heart and Stroke Foundation of Canada, the Canadian Institutes of Health Research, and the Canadian Diabetes Association ─ demonstrates that CNTF protects against some of the effects of obesity.

It does this by activating an enzyme, skeletal muscle AMP kinase, which increases the ability of the body to metabolize fat and sugar. This work may lead to new strategies to reduce the risk of metabolic abnormalities associated with excess weight.

Dr. Steinberg's research shows how CNTF activates similar pathways to those stimulated by exercise.

"While hormones such as leptin were initially thought to be the cure-all for weight loss, they were later found to be ineffective in obesity due to the presence of proteins which inhibit their ability to stimulate fat metabolism," says Dr. Steinberg, a Canadian researcher at the University of Melbourne, Australia. "Fortunately, CNTF's effects on fat burning are maintained."

Nearly half of all adult Canadians are overweight or obese and 26 per cent of Canadian children and adolescents aged two to 17 are overweight or obese. From 1985 to 2000, 57,000 deaths in Canada were associated with overweight and obesity.

"The incidence of obesity in Canada has more than doubled over the course of the last 20 years and is a major contributor to cardiovascular risk factors including diabetes and elevated blood fats," says Dr. Ruth McPherson, Heart and Stroke Foun
'"/>

Contact: Marie-France Poirier
mediarelations@cihr-irsc.gc.ca
613-941-4563
Canadian Institutes of Health Research
13-Apr-2006


Page: 1 2

Related medicine news :

1. 1 of 2 pediatric kidney disease research centers in world established
2. Stanford researchers find culprit in aging muscles that heal poorly
3. UCLA researchers awarded $9M contract for study identifiying antibiotic treatment for MRSA
4. Indiana University Imaging Center receives $6M grant for kidney research
5. Penn researchers discover novel pathway for increasing good cholesterol
6. New research discovers independent brain networks control human walking
7. Theory of facial aging gets a facelift from UT Southwestern researchers
8. Sports concussion research using fMRI provides insight for safe return-to-play decisions
9. UIC researchers to develop new drugs to fight bioterrorism
10. New research finds high prevalence of smoking among physicians in China
11. Fat is the new normal, FSU researcher says

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: