HOME >> MEDICINE >> NEWS
New study demonstrates that Lubiprostone may improve symptom relief rates in adults with IBS-C

Washington, D.C. May 21, 2007 -- A new study demonstrated that the active ingredient in AMITIZA (lubiprostone), given 8 mcg twice a day, may improve symptom relief rates in adults with irritable bowel syndrome with constipation (IBS-C). These results were presented as a late-breaker at Digestive Disease Week 2007, the largest annual international meeting of digestive disease specialists.

"In this study, patients receiving lubiprostone were nearly twice as likely to achieve an overall response from symptoms of IBS-C compared to those receiving placebo," said Douglas A. Drossman, M.D., primary investigator, UNC Center for Functional GI and Motility Disorders, University of North Carolina, and the Chair of the Rome Committee. "As a result, lubiprostone may represent an important treatment for IBS-C sufferers."

IBS is a condition that affects approximately 58 million Americans and accounts for 25-50 percent of referrals to gastroenterologists. IBS-C symptoms include abdominal pain or discomfort associated with defecation or a change in bowel habits with features of disordered defecation.

Lubiprostone is a novel selective chloride channel activator that has been shown to be effective and well-tolerated in a number of well-controlled clinical trials in patients with chronic idiopathic constipation. Lubiprostone is marketed in the U.S. as AMITIZA, a 24-mcg gelcap that was approved for use for chronic idiopathic constipation in adults on January 31, 2006.

Sucampo Pharmaceuticals expects to submit a supplemental New Drug Application for IBS-C to the U.S. Food and Drug Administration by July 2007.

About the Study for IBS-C (lubiprostone 8 mcg)

In two phase III, multi-center, double-blind, randomized, placebo-controlled trials, 1,171 adults diagnosed with IBS-C (Rome II Criteria) were enrolled and received lubiprostone 8 mcg taken twice daily (783 adults) or placebo (388 adults) over a 12-week period.


'"/>

Contact: Amy Losak
amy.losak@ketchum.com
646-935-3917
Ketchum
21-May-2007


Page: 1 2

Related medicine news :

1. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals
2. Penn study finds pro-death proteins required to regulate healthy immune function
3. New study shows promise in reducing surgical risks associated with surgical bleeding
4. New study counts the economic cost of persistent pain in Australia
5. UCLA researchers awarded $9M contract for study identifiying antibiotic treatment for MRSA
6. Most seniors now have drug coverage, U-M study shows
7. To gain muscle and lose fat, drink milk: study
8. Wheres the beef? Not enough of it is on elders plates, muscle-metabolism study suggests
9. Even older women at high risk have little interest in being tested for HIV, study finds
10. Metabolic study in mice could lead to good cholesterol boosters
11. Michigan-CDC study supports value of social restrictions during influenza pandemics

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/21/2017)... , ... September 21, 2017 , ... Japanese Zen artist ... Mat Revolution” on 6th, 7th and 8th October at Miranda Kuo Gallery on Lower ... art pieces, such as Zen Kodo mat. Wanderlust , one of the largest ...
(Date:9/21/2017)... ... 2017 , ... In the inaugural 30-minute podcast of the ... Education Gregory A. Smith examines student privacy issues with University of Colorado Boulder ... Privacy, and the Failure of Policymaking . , Join Smith and Boninger ...
(Date:9/20/2017)... Calif. (PRWEB) , ... September 20, 2017 , ... ... year of providing a voice for people who have kidney disease. The theme ... writers to share their stories. Entrants needed to meet only one qualification— ...
(Date:9/20/2017)... (PRWEB) , ... September 20, 2017 , ... ... the Orthodontics and Clear Aligner clinical and commercial support services market) has entered ... Dentistry (PGSD) in Sydney, Australia. , The PGSD is the first private ...
(Date:9/20/2017)... ... September 20, 2017 , ... ... campaign, “Humans With Vaginas.” The goal is to ignite conversation via social media ... care products. The brand has declared September “Humans with Vaginas” month, releasing a ...
Breaking Medicine News(10 mins):
(Date:9/12/2017)... N.J. , Sept. 12, 2017  Consumer reviews on the ... Hearing as the number one company for hearing aids, ranking ... and fifteen other brands. ... Embrace Hearing Named #1 by Consumers For Hearing Aids ... Embrace Hearing is an online store that provides high ...
(Date:9/9/2017)... , Sept. 8, 2017 Dealmed Medical Supplies, ... supplier of medical equipment, supplies, drugs, vaccines, and specialty ... entered into an agreement to acquire Vantage Medical Supplies, ... in Holtsville, New York . ... supplying new and emerging medical practices, will operate under ...
(Date:9/7/2017)... MIRAGE, Calif. , Sept. 7, 2017  For nearly two decades, ... service in the Assisted Reproduction Insurance industry. Today, New Life Agency announces ... fertility medications. ... http://pharmacarecard.com/ (PRNewsfoto/PharmaCareCard) ... ...
Breaking Medicine Technology:
Cached News: