New technology to speed up research into Huntington's disease

A new tool developed at Cambridge University represents a breakthrough in the race to find treatments to help sufferers with Huntington's disease.

Researchers have developed an effective new method of testing cognitive decline in mice with the disease, using an automated touch screen. It is hoped the screen will also allow researchers to study more effectively the cognitive difficulties in other neurodegenerative disorders such as in Alzheimer's and CJD.

Huntington's disease is a genetic disease affecting around 8 in 100,000 people. It is characterised by a progressive decline in cognitive functioning (including memory loss, intellectual decline and disorientation) together with the appearance of abnormal movements and impaired motor skills (such as unsteady gait and poor coordination).

There is currently no cure and whilst some symptoms can be alleviated, no treatments have been developed that help with cognitive deficits, a distressing aspect of the disease.

Whilst useful mouse models mimicking this disorder have been developed, it has been difficult to test cognitive skills such as learning, because most traditional experiments demand a level of physical performance that the mice cannot deliver due to the effect of the disease on their motor abilities.

The automated screen developed by Cambridge scientists provides a simple means of assessing cognition, in a way that requires minimal movement on the part of the mouse. The mouse makes its response by touching its nose to the touch-sensitive screen. This means that the HD mice can complete the task, despite motor problems.

Other benefits are that it is less labour intensive, less time consuming and less stressful for mice, compared to traditional testing methods. Given the difficulties associated with these traditional methods, progress to date in trialling new treatments for cognitive deficits has been slow with contract research organisations und

Contact: Leila Coupe
University of Cambridge

Page: 1 2 3

Related medicine news :

1. Wireless technology shows promise in diagnosing pediatric intestinal disease
2. Speeding up CT scans with cellphone technology, ultrasound warning signal for breast cancer
3. E/Tablet technology may provide benefits to patients, researchers
4. New Mayo Clinic MRI technology enables noninvasive liver diagnoses
5. SCAI highlights study using wireless technology to speed care of heart attack patients
6. UQ research heralds vaccine technology breakthrough
7. Plasmonics book gives overview of technology that could revolutionize computing
8. New biotech company to commercialize novel UD gene-repair technology
9. ACP supports new bill to promote adoption of health information technology
10. Adoption of health information technology will lead to higher standard of quality care
11. Research agreement to advance new imaging technology

Post Your Comments:
TAG: New technology speed research into Huntington disease

(Date:10/9/2015)... ... October 09, 2015 , ... ... promotion on Invisalign, the orthodontic system that uses clear, plastic aligners. This alternative ... invisible against the teeth, which allow patients to complete treatment in privacy. Additionally, ...
(Date:10/9/2015)... ... October 09, 2015 , ... The Asthma and Allergy Foundation ... for Disease Control and Prevention (CDC) to improve the knowledge and skills of underserved ... been awarded a project by the CDC and allows AAFA to continue vital efforts ...
(Date:10/9/2015)... ... October 09, 2015 , ... ... welcoming individuals from all walks of life to save money on the high ... of $25 per month per medication, individuals and families can receive their medications ...
(Date:10/9/2015)... ... October 09, 2015 , ... ... oldest and largest recreational dispensaries in Colorado, says the latest figures on the ... rapidly and maturing into a legitimate industry. , Last month, according to ...
(Date:10/9/2015)... ... , ... Smanos was featured on NewsWatch as part of its monthly Tech ... a technology expert and special reporter for NewsWatch, conducted the review and shared with ... this day and age it’s more important than ever to keep homes and dorms ...
Breaking Medicine News(10 mins):
(Date:10/9/2015)... India , October 9, 2015 ... analysis of major players. --> ... players. --> RnRMarketResearch.com announces addition of ... status and 2020 forecasts for global markets as ... India along with analysis of major ...
(Date:10/9/2015)... 2015 Henry Schein , Inc. (NASDAQ: ... care products and services to office-based dental, animal health ... Henry Schein Disaster Relief Hotline is open for dentists, ... issues as a result of the disastrous flooding in ... for all Henry Schein customers is 800-999-9729. ...
(Date:10/9/2015)... , Oct. 9, 2015  Impax Laboratories, Inc. ... will release its third quarter 2015 financial results on ... the U.S. financial markets. The Company will host a ... at 8:30 a.m., Eastern Time on November 9, 2015.  ... . --> The financial results and live ...
Breaking Medicine Technology:
Cached News: