HOME >> MEDICINE >> NEWS
New technology to speed up research into Huntington's disease

A new tool developed at Cambridge University represents a breakthrough in the race to find treatments to help sufferers with Huntington's disease.

Researchers have developed an effective new method of testing cognitive decline in mice with the disease, using an automated touch screen. It is hoped the screen will also allow researchers to study more effectively the cognitive difficulties in other neurodegenerative disorders such as in Alzheimer's and CJD.

Huntington's disease is a genetic disease affecting around 8 in 100,000 people. It is characterised by a progressive decline in cognitive functioning (including memory loss, intellectual decline and disorientation) together with the appearance of abnormal movements and impaired motor skills (such as unsteady gait and poor coordination).

There is currently no cure and whilst some symptoms can be alleviated, no treatments have been developed that help with cognitive deficits, a distressing aspect of the disease.

Whilst useful mouse models mimicking this disorder have been developed, it has been difficult to test cognitive skills such as learning, because most traditional experiments demand a level of physical performance that the mice cannot deliver due to the effect of the disease on their motor abilities.

The automated screen developed by Cambridge scientists provides a simple means of assessing cognition, in a way that requires minimal movement on the part of the mouse. The mouse makes its response by touching its nose to the touch-sensitive screen. This means that the HD mice can complete the task, despite motor problems.

Other benefits are that it is less labour intensive, less time consuming and less stressful for mice, compared to traditional testing methods. Given the difficulties associated with these traditional methods, progress to date in trialling new treatments for cognitive deficits has been slow with contract research organisations und
'"/>

Contact: Leila Coupe
lc401@admin.cam.ac.uk
1-223-765-542
University of Cambridge
6-Oct-2006


Page: 1 2 3

Related medicine news :

1. Wireless technology shows promise in diagnosing pediatric intestinal disease
2. Speeding up CT scans with cellphone technology, ultrasound warning signal for breast cancer
3. E/Tablet technology may provide benefits to patients, researchers
4. New Mayo Clinic MRI technology enables noninvasive liver diagnoses
5. SCAI highlights study using wireless technology to speed care of heart attack patients
6. UQ research heralds vaccine technology breakthrough
7. Plasmonics book gives overview of technology that could revolutionize computing
8. New biotech company to commercialize novel UD gene-repair technology
9. ACP supports new bill to promote adoption of health information technology
10. Adoption of health information technology will lead to higher standard of quality care
11. Research agreement to advance new imaging technology

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New technology speed research into Huntington disease

(Date:9/1/2015)... ... ... Agriculture innovation, urban farming, local food access, and sourcing from sustainable and ... 4th Annual Sustainable Agriculture Conference : “Innovation and the Rise of Local Food,” ... keynotes Pierre Sleiman, founder and CEO of Go Green Agriculture, and Daron “Farmer D” ...
(Date:9/1/2015)... ... September 01, 2015 , ... METTLER TOLEDO ... available. With the Connectivity Kit, EasySampler data is automatically transferred to, and ... experiment, on a touchscreen platform. , EasySampler fully automates the sampling process ...
(Date:9/1/2015)... (PRWEB) , ... September 01, 2015 , ... ... date, more than 1,500 investor-families have received permanent green cards (I-829 petition approval) ... , The I-829 petition is the final step of the EB-5 visa process ...
(Date:9/1/2015)... Beach, FL (PRWEB) , ... September 01, 2015 ... ... pharmacy discount cards, launched its consumer-friendly, informational video this week to coincide with ... http://www.USAMedicalCard.com/video . , According to the CDC, elementary school children are ...
(Date:9/1/2015)... ... September 01, 2015 , ... AdvantagePlusCaregivers.com® ... to access caregivers and what to look for and expect when searching for ... Founded in 2006 in Canoga Park, CA by CEO, Richard Weatherman and Co-Founder ...
Breaking Medicine News(10 mins):Health News:Experts in Urban and Local Food Systems Development to Address Seedstock Sustainable Agriculture Conference Nov. 3-4 Discounted ticket sales end Sept. 4 2Health News:Experts in Urban and Local Food Systems Development to Address Seedstock Sustainable Agriculture Conference Nov. 3-4 Discounted ticket sales end Sept. 4 3Health News:Experts in Urban and Local Food Systems Development to Address Seedstock Sustainable Agriculture Conference Nov. 3-4 Discounted ticket sales end Sept. 4 4Health News:Experts in Urban and Local Food Systems Development to Address Seedstock Sustainable Agriculture Conference Nov. 3-4 Discounted ticket sales end Sept. 4 5Health News:New Technology Allows Unattended Sampling and Synthesis of Chemical Reactions 2Health News:New Technology Allows Unattended Sampling and Synthesis of Chemical Reactions 3Health News:CanAm Enterprises Reaches Another Milestone with More Than 1,500 I-829 Petition Approvals 2Health News:USA Medical Card Launches New FAQ Video During Back-to-School 2Health News:AdvantagePlusCaregivers.com® Launches New Website for Corporate and Franchisee Locations in 3 States 2
(Date:9/1/2015)... 1, 2015 Within just two years after ... has rapidly reached 3,000 employees worldwide. This increase ... the injectable drug delivery market and SHL,s effective ... leader in the design and manufacturing of auto ... robust manufacturing capabilities, a lean supply chain, strong ...
(Date:9/1/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/r8v22b/regulatory ) ... for Support Staff (London, UK - September 24-25, 2015)" ... two day course provides an introduction to Pharmaceutical Regulatory ... been designed specifically for those working in a support ... overview of EU regulatory procedures required to register products ...
(Date:9/1/2015)... 1, 2015 Pressure BioSciences, Inc. (OTCQB: ... the development and sale of broadly enabling, pressure ... worldwide life sciences industry, today announced the publication ... Company,s PCT Platform could play a significant role ... role is based on PCT,s unique ability to ...
Breaking Medicine Technology:SHL Group Reaches Major Milestone of 3000 Employees 2Regulatory Affairs for Support Staff Seminar (London, UK - September 24-25, 2015) 2New Scientific Publication Suggests Pressure BioSciences' PCT Platform Could Play Significant Role in Personalized/Precision Medicine 2New Scientific Publication Suggests Pressure BioSciences' PCT Platform Could Play Significant Role in Personalized/Precision Medicine 3New Scientific Publication Suggests Pressure BioSciences' PCT Platform Could Play Significant Role in Personalized/Precision Medicine 4New Scientific Publication Suggests Pressure BioSciences' PCT Platform Could Play Significant Role in Personalized/Precision Medicine 5
Cached News: