HOME >> MEDICINE >> NEWS
New therapeutic targets for neurodegenerative diseases

The focus of work in the Neurosciences Departments Neurobiology Laboratory at the University of the Basque Countrys Faculty of Medicine and Odontology is the investigation of the molecular and cellular bases of neurodegenerative illnesses those that affect the brain and the spinal cord. Some of these neurodegenerative illnesses are well known and affect a significant part of the population, such as Alzheimers disease and multiple sclerosis.

Researchers at the University of the Basque Country (UPV-EHU) are studying the signals in the central nervous system - the brain and the spinal cord - that do not function well, in particular, those signals that cause the death of nerve cells. There are basically two types of cells in the central nervous system: neurones and the glial cells. Both types are sensitive to these functioning errors and both can die. In the case of Alzheimers disease, it is the neurones, above all, that die. However, in the case of multiple sclerosis, it is a class of glial cells known as oligodendrocytes that perish.

From in vitro cells to biological samples of human origin

The researchers at the Neurobiology Laboratory are investigating cells in cultures - neurones, oligodendrocytes or other cells of the nervous system -, and are trying to reproduce in vitro circumstances that are thought to be relevant in these ailments. That is to say, they are creating the conditions that cause the death of these cells, in order to determine what molecules intervene in the process from the moment of the lethal signal to the point where the cells collapse. In this type of experimental work a series of molecules involved in the death process are identified, the aim being to come up with pharmaceutical medicines that will improve treatment.

Apart from working with in vitro cells, they are also experimenting with animals that reproduce some of the elements involved in neurodegenerative illnesses u
'"/>

Contact: Irati Kortabitarte
iratik@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
10-May-2007


Page: 1 2 3

Related medicine news :

1. Shark cartilage shows no benefit as a therapeutic agent for lung cancer
2. OCT1 required for therapeutic effects of diabetes drug Metformin
3. NeuroRx changes name to Neurotherapeutics
4. Olive Leaf report documents promising therapeutic interventions for 9-11 workers
5. T cells activated to fight HIV basis for dendritic cell therapeutic vaccine
6. Cerebrospinal fluid used to deliver therapeutics for Lou Gehrigs disease to brain
7. University to develop new therapeutics for cancer
8. Exubera: So far no evidence available of an additional therapeutic benefit
9. Nano-particles effective in killing cancer with one-two punch of chemotherapeutics
10. Researchers identify target for therapeutic drugs to fight most common adult brain cancer
11. Cedars-Sinai researchers demonstrate a new way to switch therapeutic genes on and off

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New therapeutic targets for neurodegenerative diseases

(Date:12/22/2014)... CA (PRWEB) December 22, 2014 ... now offering consultations for sleep apnea. Drowsy drivers are ... than drivers who are well-rested, and some experts believe ... the roads as intoxicated drivers. Unfortunately, millions of Americans ... the American Academy of Sleep Medicine, about 18 million ...
(Date:12/22/2014)... Luxury Linen purveyor Peacock Alley ... to provide logistics and support for one of Dallas’ ... a long history of giving back to the community in ... year's Toy Drive were Whataburger® and 99.5 The Wolf. , ... holidays. Providing gifts to children who would otherwise not receive ...
(Date:12/22/2014)... 21, 2014 A substantial percentage ... computed tomography (CT) to evaluate abnormal findings on ... cancer, according to a new study published online ... the findings show that radiologist recommendations for additional ... to patient care. , RAIs, which have grown ...
(Date:12/21/2014)... (PRWEB) December 22, 2014 In ... is segmented by power source, product, and application. ... electric-powered, battery-powered, and pneumatic instruments. By product, the ... and accessories segments. The handpieces market is further ... devices, suction coagulators, laparoscopic instruments, shavers, wire/pin drivers, ...
(Date:12/21/2014)... 2014 Khanna Vision Institute is pleased ... the Aspen Helicopters holiday event for underprivileged kids. The ... sleigh, flown by an aspen helicopter pilot. In the ... with sleigh was visible.(please see accompanying video). Helicopter pilots ... has helped many pilots with Pi in eye vision ...
Breaking Medicine News(10 mins):Health News:Pasadena Dentist, Dr. Marine Martirosyan, Now Offers Consultations for Sleep Apnea 2Health News:Peacock Alley and Community Partners of Dallas Fulfill an Estimated 12,000 Holiday Wishes for Deserving Children 2Health News:RSNA: Radiologist Recommendations for Chest CT Have High Clinical Yield 2Health News:RSNA: Radiologist Recommendations for Chest CT Have High Clinical Yield 3Health News:Global Powered Surgical Instruments Market Hit to $2.1 billion by 2019 - New Research Report by MarketsandMarkets 2Health News:Global Powered Surgical Instruments Market Hit to $2.1 billion by 2019 - New Research Report by MarketsandMarkets 3Health News:Global Powered Surgical Instruments Market Hit to $2.1 billion by 2019 - New Research Report by MarketsandMarkets 4
(Date:12/22/2014)... /PRNewswire/ -- RXi Pharmaceuticals Corporation (NASDAQ: RXII ... and commercializing innovative therapies addressing major unmet medical ... open letter to shareholders from President & CEO, ... Dear RXi Shareholders, In the ... posted on certain social media sites seem to ...
(Date:12/22/2014)... 2014 TWi Biotechnology, Inc., today announced ... AC-201, TWi Biotechnology,s lead drug candidate, from The ... for patent application numbered 201180018154.8.  This ... active metabolite for treatment of type II diabetes.  ... using AC-201 for type II diabetes, and provides ...
(Date:12/19/2014)... KENNEWICK, Wash. , Dec. 19, 2014 /PRNewswire/ ... late stage development company engaged primarily in the ... diagnostic and therapeutic applications, today announced that a ... Grant has been awarded for which AMIC is ... Washington State University (WSU) for the proposal titled ...
Breaking Medicine Technology:RXi Pharmaceuticals Issues Open Letter to Shareholders 2RXi Pharmaceuticals Issues Open Letter to Shareholders 3RXi Pharmaceuticals Issues Open Letter to Shareholders 4RXi Pharmaceuticals Issues Open Letter to Shareholders 5RXi Pharmaceuticals Issues Open Letter to Shareholders 6TWi Biotechnology Receives Notice of Patent Allowance for Its Lead Drug Candidate AC-201 for the Indication of Type II Diabetes in China 2TWi Biotechnology Receives Notice of Patent Allowance for Its Lead Drug Candidate AC-201 for the Indication of Type II Diabetes in China 3Advanced Medical Isotope Corporation Awarded LSDF Grant As Commercialization Partner 2Advanced Medical Isotope Corporation Awarded LSDF Grant As Commercialization Partner 3
Cached News: