HOME >> MEDICINE >> NEWS
New treatment effective in counteracting cocaine-induced symptoms

DALLAS Aug. 13, 2007 UT Southwestern Medical Center researchers have discovered a treatment that counteracts the effects of cocaine on the human cardiovascular system, including lowering the elevated heart rate and blood pressure often found in cocaine users.

We have found that cocaines effects on the cardiovascular system can be reversed by the use of a drug called dexmedetomidine, which is currently approved by the Food and Drug Administration for anesthetic purposes in operating rooms or intensive care units, said Dr. Wanpen Vongpatanasin, associate professor of internal medicine and senior author of a study appearing in the Aug. 14 issue of the Journal of the American College of Cardiology.

Researchers used dexmedetomidine to test whether cocaines effect on the cardiovascular system could be muted. They found that the drug was effective in reversing the actions of cocaine on heart rate, blood pressure and vascular resistance in the skin by interfering with the ability of cocaine to increase nerve activity.

Typically, patients with cocaine overdoses in the emergency room are treated with nitroglycerin, sedatives such as Valium, and some blood-pressure medications such as calcium channel blockers and some beta blockers, Dr. Vongpatanasin said. However, the standard treatments dont alleviate all of the adverse effects of cocaine on the heart, blood pressure and central nervous system.

The study examined results from 22 healthy adults who reported to have never used cocaine. The investigators administered a small, medically approved dose of cocaine nose drops to the study participants, which doubled their sympathetic nerve activity, part of the bodys automatic response system that becomes more active during times of stress. Participants experienced increases in several cardiovascular parameters including heart rate, blood pressure and resistance to blood flow in the skin.

Microelectrodes, similar to acupuncture needles, were used
'"/>

Contact: Katherine Morales
katherine.morales@utsouthwestern.edu
214-638-3404
UT Southwestern Medical Center
13-Aug-2007


Page: 1 2

Related medicine news :

1. Spot on treatment for acne
2. New treatment boosts muscle function in myasthenia gravis
3. UCLA researchers awarded $9M contract for study identifiying antibiotic treatment for MRSA
4. Preventive treatments in elderly people needs rethinking
5. Osteoporosis screening and treatment may be cost-effective for selected older men
6. Quality of treatment guidelines
7. Green tea holds promise as new treatment for inflammatory skin diseases
8. Many heart attack patients still not getting emergency clot-busting treatment
9. Electric fields have potential as a cancer treatment
10. New algorithm matches any tumor cells to best possible anti-cancer treatments
11. Screening for behavioral health first step to getting treatment

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/13/2019)... ... ... With Valentine’s Day tomorrow and love in the air, myLAB Box ... to ensure ‘Safe Sex’: , 1. Talk To Your Partner. Communication is important ... clear, open, and honest communication is key so that both partners are able to ...
(Date:2/13/2019)... (PRWEB) , ... February 13, 2019 , ... Diameter ... LLC has been issued a Federal Information Security Management Act (FISMA) High General Support ... This validation of a secure environment is mandatory for the VA because of their ...
(Date:2/13/2019)... , ... February 13, 2019 , ... Castle announced today ... with participation from existing investors Y Combinator , First Round and ... COO at Duo Security, René Bonvanie, CMO at Palo Alto Networks, and Olivier Pomel, ...
(Date:2/13/2019)... ... February 13, 2019 , ... ... practice management organizations in the nation, announced a new addition to their growing ... stand-alone oculofacial center created within a multi-specialty ophthalmology practice. , Dr. ...
(Date:2/13/2019)... ... , ... A Place at Home has received the 2019 Best ... of Choice Award is granted only to the top-ranking home care providers, based on ... home care. A Place at Home is ranked among the best employers of in-home ...
Breaking Medicine News(10 mins):
(Date:2/14/2019)... ... February 14, 2019 , ... Neptune Society’s new location in Fort Worth, ... house and ribbon-cutting ceremony on Thursday, February 21, 2019. Members of the community can ... , Guests may RSVP by calling the office directly at (817) 838-5100. , The ...
(Date:2/13/2019)... LOUISVILLE, Ky. (PRWEB) , ... February 13, 2019 ... ... 20 thousandth patient! The clinic opened their doors in November of 2013 and, ... premature ejaculation, low testosterone, and Peyronies Disease. With an over 90% success rate, ...
(Date:2/13/2019)... Utah (PRWEB) , ... February 13, 2019 , ... ... data management and population health reporting solutions, is launching IMAT 8.0, its latest ... matching, along with a more streamlined user interface and dynamic single-query builder, IMAT ...
Breaking Medicine Technology:
Cached News: