HOME >> MEDICINE >> NEWS
New 'wrinkle' in Botox treatment could lead to lower doses, better safety

There may soon be a better way to fight unsightly wrinkles. Researchers have discovered a novel way to increase the potency of botulinum neurotoxin treatments commonly known as Botox that they say could one day allow patients to receive the injections less frequently while maintaining or even enhancing its cosmetic benefits.

By allowing lower doses, the new approach could also make the treatment safer by reducing the risk of complications associated with immune system recognition that can sometimes occur with frequent injections, according to scientists at the Scripps Research Institute in La Jolla, Calif. Smaller, more potent doses may even lead to lower prices for the popular wrinkle-remover, the researchers say. Their study is published in the March 29 issue of the weekly Journal of the American Chemical Society.

Although popular for removing wrinkles, Botox is also used to treat a growing number of other conditions, including migraine headaches, lazy eyes and excessive sweating. It is developed from the botulinum neurotoxin, the most lethal poison known and a potential bioterrorist weapon. In a medical setting, small doses of a purified version of the toxin block the release of a chemical (acetylcholine) that signals muscle contraction, resulting in a localized, temporary paralysis that erases wrinkles and unwanted muscle spasms.

Kim Janda, Ph.D., a chemistry professor at Scripps and head of the research study, and his associates developed a synthetic molecule that can superactivate the neurotoxin used in Botox by binding to specific sites on the neurotoxin protein. The synthetic molecule works by increasing the activity of an enzyme that cleaves proteins that are critical for neurotransmitter release, thereby increasing the blockage of acetylcholine and enhancing the toxins paralyzing effect. In laboratory studies, the researchers found that this superactivator could boost the activity of the to
'"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-4400
American Chemical Society
5-Apr-2006


Page: 1 2

Related medicine news :

1. Botox: More than cosmetic
2. Study shows Botox decreases pain and intensity of spasticity following a stroke
3. Botox can ease writers cramp
4. Botox injections may improve facial-wound healing, minimize scars
5. Botox: Its not just for wrinkles anymore
6. Botox for more than ironing wrinkles
7. Botox injections effective for treating stroke spasticity
8. Botox stops severe drooling in children with neurologic conditions
9. Spot on treatment for acne
10. New treatment boosts muscle function in myasthenia gravis
11. New treatment effective in counteracting cocaine-induced symptoms

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New wrinkle Botox treatment could lead lower doses better safety

(Date:10/22/2014)... 2014 (HealthDay News) -- The United States is ... Ebola-affected nations of West Africa land at one ... infection with the virus. In a statement ... that 94 percent of air passengers from Guinea, ... of these five airports -- New York City,s ...
(Date:10/22/2014)... Los Angeles, California (PRWEB) October 22, 2014 ... Recovery 2.0: Move Beyond Addiction and Upgrade Your Life (Paperback; ... the field of Yoga & Recovery. This book is ... and thrive in a life of recovery. , Recovery ... of the 12 Steps; Recovery 2.0 is a guide for ...
(Date:10/22/2014)... 22, 2014 Best Cheap Hosting USA ... world. The site has recently announced that iPower ( ... for people from around the world. , “iPower is ... today and is providing various kinds of useful products ... insists on offering excellent customer service and a number ...
(Date:10/22/2014)... Although there are only 24 hours in a ... who have trouble finding time within their busy schedules for exercise ... periods of time to get in shape. Here are five ways ... go. , Change Up Your Commute , Consider riding a ... some exercise into your daily routine. If you must use your ...
(Date:10/22/2014)... 22, 2014 Akeso Biomedical, Inc. ... the treatment of bacterial infections, microbial biofilms, and chronic ... its board of directors. , Dr. Sinskey ... at The Massachusetts Institute of Technology, or MIT. He ... 1968. Dr. Sinskey also holds positions as Co-Director of ...
Breaking Medicine News(10 mins):Health News:Passengers From Ebola-Affected Countries Must Land at Designated U.S. Airports 2Health News:Passengers From Ebola-Affected Countries Must Land at Designated U.S. Airports 3Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 2Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 3Health News:Best Cheap Hosting USA Has Recently Announced The Best Cheap Web Hosting Companies In 2014 2Health News:HealthGuideMD Presents Ways to Improve Your Exercise and Fitness 2Health News:Akeso Biomedical Appoints Dr. Anthony J. Sinskey to Board of Directors 2
(Date:10/22/2014)... -- Abaxis, Inc. (NasdaqGS: ABAX ), a ... reported financial results for the second fiscal quarter ended ... , Revenues of $53.9 million, up 18% over last ... up 33% over last year,s comparable quarter. ... Reference Laboratories (AVRL) of $3.5 million, up 50% over ...
(Date:10/22/2014)... Sanomedics International Holdings, Inc. (OTCQB: SIMH) – ... & Data Services, demand for thermometers is expected to ... as demand for more accurate digital thermometers continues.  ... largest market for thermometers, and one of the companies ... Holdings, Inc. Sanomedics International Holdings designs, develops, ...
(Date:10/22/2014)... CITY, Calif. , Oct. 22, 2014 /PRNewswire/ ... today announced that results from the  IAP310 study ... Pain Medicine (RAPM), a peer-reviewed journal with ... Phase 3 trial evaluating the safety and efficacy ... sublingual tablet system (SSTS), for the treatment of ...
Breaking Medicine Technology:Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 2Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 3Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 4Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 5Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 6Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 7Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 8Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 9Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 10Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 11Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 12Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 13Abaxis Reports Record Revenues for the Second Quarter of Fiscal 2015 14Sanomedics International Holdings Analyst Report: Taking Some Heat by BrokerBank Securities, Inc. 2AcelRx Announces Publication of Zalviso Phase 3 Abdominal Trial Results 2
Cached News: